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anti-G Protein-Coupled Receptor 68 (GPR68) Antibodies

Proton-sensing receptor involved in pH homeostasis. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR68 8111 Q15743
GPR68 238377 Q8BFQ3
GPR68 314386  
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Top anti-GPR68 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated Func, IHC (fro), WB 0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB Mouse Gpr68 Antibody (Center) (ABIN1881516) western blot analysis in mouse liver and heart tissue lysates (35 µg/lane). This demonstrates the Mouse Gpr68 antibody detected the Mouse Gpr68 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-GPR68 antibody  ABIN1048861 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-GPR68 antibody  ABIN1048865 IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IC, IF, WB Western blot analysis of GPR68 expression in HeLa (A), mouse spleen (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details

GPR68 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , ,


Rat (Rattus) , ,


Top referenced anti-GPR68 Antibodies

  1. Mouse (Murine) Polyclonal GPR68 Primary Antibody for WB - ABIN1881516 : Singh, Berk, Oates, Zhao, Tan, Jiang, Zhou, Kirmani, Steinmetz, Lindner, Xu: Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer. in Journal of the National Cancer Institute 2007 (PubMed)
    Show all 4 references for ABIN1881516

  2. Human Polyclonal GPR68 Primary Antibody for IHC (p) - ABIN1048863 : Komarova, Pereverzev, Shum, Sims, Dixon: Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 3 references for ABIN1048863

  3. Human Polyclonal GPR68 Primary Antibody for Func, IHC (fro) - ABIN265065 : Xu, Zhu, Hong, Wu, Baudhuin, Xiao, Damron: Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1. in Nature cell biology 2000 (PubMed)

More Antibodies against GPR68 Interaction Partners

Human G Protein-Coupled Receptor 68 (GPR68) interaction partners

  1. The deconstruction of OGR1-dependent signaling may aid our understanding of mucosal inflammation mechanisms

  2. Provide evidence for the roles of OGR1 and ASIC1a (show ACCN2 Antibodies) in the regulation of intestinal passive Mg(2 (show MUC7 Antibodies)+) absorption.

  3. the expression of OGR1 in myeloid-derived cells, especially in double positive cells, was required for prostate tumor cell-induced immunosuppression.

  4. The involvement of ovarian cancer G-protein-coupled receptor 1 in acidic extracellular environment may be an underlying mechanism responsible for bone pain in osteoporosis or bone metastasis without clinically proved fractures.

  5. OGR1 activation increased intracellular calcium in transfe (show ATP6AP1 Antibodies)cted HEK293 cells.

  6. It indicated that OGR1 may be a tumor suppressor gene for ovarian cancer.

  7. extracellular acidification induces CTGF (show CTGF Antibodies) production through the OGR1/G(q/11) protein and inositol-1,4,5-trisphosphate-induced Ca(2 (show CA2 Antibodies)+) mobilization in human airway smooth muscle cells.

  8. acidic pH-induced vascular actions of aortic smooth muscle cells can be dissected to OGR1-dependent and -independent pathways: COX-2 (show COX2 Antibodies) expression, PGI(2 (show PTGIR Antibodies)) production, and MKP-1 (show DUSP1 Antibodies) expression are mediated by OGR1, but PAI-1 (show SERPINE1 Antibodies) expression is not.

  9. ovarian cancer G-protein-coupled receptor 1 (OGR1), previously described as a receptor for sphingosylphosphorylcholine, acts as a proton-sensing receptor stimulating inositol phosphate formation

  10. OGR1 was found to evoke strong pH-dependent responses as measured by inositol phosphate accumulation.

Mouse (Murine) G Protein-Coupled Receptor 68 (GPR68) interaction partners

  1. Here, we demonstrate that metals, Fe, Zn, Co, Ni and Mn are the novel OGR1 agonists, which can singly activate OGR1 in neutral pH.

  2. CaSR (show CASR Antibodies) and OGR1 reciprocally inhibit signaling through each other in central neurons, and that this is lost in their transformed counterparts. Acidification potentiates OGR1.

  3. acidic pH stimulates cGMP accumulation preferentially through the OGR1/Gq/11 proteins/phospholipase C (show PLC Antibodies)/Ca(2 (show CA2 Antibodies)+)/nNOS (show NOS1 Antibodies) in N1E-115 neuronal cells. Akt (show AKT1 Antibodies)-mediated phosphorylation of nNOS (show NOS1 Antibodies)

  4. OGR1 on dendritic cells is critical for their migration to draining lymph nodes, which, in turn, stimulates Th2 phenotype change and subsequent induction of airway inflammation and hyperreactivity.

  5. Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin (show INS Antibodies) secretion.

  6. OGR1 alters the pH-sensitive response of NHE and H+-ATPase (show ATP6AP1 Antibodies) activity in proximal tubules.

  7. regulator of G-protein signaling 18 (show RGS18 Antibodies) acts as a negative regulator of the acidosis-induced osteoclastogenic OGR1/NFAT (show NFATC1 Antibodies) signaling pathway

  8. OGR1 induces an increase in Ca(i (show CA1 Antibodies)) in response to acidic medium and is a prime candidate for an osteoblast proton sensor.

  9. OGR1's role in osteoclastogenesis is not strong enough to affect overall bone development.

GPR68 Antigen Profile

Protein Summary

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (By similarity). Function also as a metastasis suppressor gene in prostate cancer (By similarity).

Gene names and symbols associated with GPR68

  • G protein-coupled receptor 68 (GPR68) antibody
  • G protein-coupled receptor 68 (LOC100348269) antibody
  • G protein-coupled receptor 68 (Gpr68) antibody
  • BB131428 antibody
  • GPR12A antibody
  • GPR68 antibody
  • Ogr1 antibody

Protein level used designations for GPR68

G protein-coupled receptor 68 , ovarian cancer G-protein coupled receptor 1-like , G-protein coupled receptor 68 , ovarian cancer G protein-coupled receptor, 1 , ovarian cancer G-protein coupled receptor 1 , sphingosylphosphorylcholine receptor , bRGR1 , g protein-coupled receptor RGR1

GENE ID SPECIES
428904 Gallus gallus
453105 Pan troglodytes
696529 Macaca mulatta
100348269 Oryctolagus cuniculus
100412989 Callithrix jacchus
100437072 Pongo abelii
100598083 Nomascus leucogenys
8111 Homo sapiens
238377 Mus musculus
314386 Rattus norvegicus
281799 Bos taurus
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