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G Protein-Coupled Receptor Associated Sorting Protein 1 Proteins (GPRASP1)

GPRASP1 encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. Additionally we are shipping G Protein-Coupled Receptor Associated Sorting Protein 1 Antibodies (34) and G Protein-Coupled Receptor Associated Sorting Protein 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPRASP1 9737 Q5JY77
GPRASP1 67298 Q5U4C1
Rat GPRASP1 GPRASP1 171407 Q920R4
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Top G Protein-Coupled Receptor Associated Sorting Protein 1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_CHO Cells Human Un-conjugated   5 μg Log in to see 10 to 12 Days
$86.96
Details
HOST_CHO Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$782.25
Details
HOST_CHO Cells Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details

GPRASP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Top referenced G Protein-Coupled Receptor Associated Sorting Protein 1 Proteins

  1. Human GPRASP1 Protein expressed in CHO Cells - ABIN2666470 : Monestier, Brun, Heu, Passet, Malhouroux, Magnol, Vilotte, Blanquet: Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype. in BMC genomics 2013 (PubMed)
    Show all 4 references for ABIN2666470

More Proteins for G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) Interaction Partners

Human G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) interaction partners

  1. Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 (show HTR7 Proteins) receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1

  2. Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2 (show DRD2 Proteins)) are involved in regulation of DRD2 (show DRD2 Proteins) endocytosis by GRK2 (G-protein coupled receptor kinase 2 (show ADRBK1 Proteins)) and GASP1.

  3. GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas.

  4. GASP-1 is a key regulator of the trafficking and, by extension, functional expression of GPR55 (show GPR55 Proteins)

  5. LIR (show CD300C Proteins) was able to induce gains in 1RM and quadriceps CSA (show ERCC8 Proteins) similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN (show MSTN Proteins) and increase in FLST isoforms, GASP-1, and SMAD-7 (show SMAD7 Proteins) mRNA gene expression.

  6. These studies identify GASP-1 as a potential new serum and tumor biomarker for breast cancer.

  7. following this endocytosis the D(3) dopamine receptors fail to recycle and are instead targeted for degradation through an interaction with the G protein-coupled receptor (GPCR (show TAS1R3 Proteins))-associated sorting protein-1 (GASP-1)

  8. identified a protein that binds preferentially to the cytoplasmic tail of the delta opioid receptor as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor (show ADRA1A Proteins)-associated sorting protein (GASP) [GASP]

  9. Modulation of the D2-GASP interaction is important for the functional down-regulation of D2 dopamine receptors.

Mouse (Murine) G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) interaction partners

  1. present the First low resolution solution structure of myostatin (show MSTN Proteins)-free and myostatin (show MSTN Proteins)-bound states of GASP-1 and GASP-2 (show WFIKKN1 Proteins)

  2. Gasp-1 overexpression resulted in increased myostatin (show MSTN Proteins) expression.

  3. GASP-1 and GASP-2 (show WFIKKN1 Proteins) are important modulators of GDF-11 (show GDF11 Proteins) and MSTN (show MSTN Proteins) activity in vivo.

  4. Overexpression of Gasp1 led to an increase in muscle mass observed not before day 15 of postnatal life.

  5. The pattern of behavioral deficits observed in GASP-1-deficient mice is coherent with current knowledge of the role of striatal G protein-coupled receptor(GPCR (show TAS1R3 Proteins))s in acquisition/expression of skilled behavior and motivation.

G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) Protein Profile

Protein Summary

This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with GPRASP1

  • G protein-coupled receptor associated sorting protein 1 (GPRASP1)
  • G protein-coupled receptor associated sorting protein 1 (Gprasp1)
  • 2210415K24Rik protein
  • 3110031O14Rik protein
  • C87852 protein
  • GASP protein
  • GASP-1 protein
  • GASP1 protein
  • MGC159823 protein
  • pips protein

Protein level used designations for GPRASP1

G protein-coupled receptor associated sorting protein 1 , G-protein coupled receptor-associated sorting protein 1 , G-protein coupled receptor-associated sorting protein 1-like , GASP-1 , Per1 interacting protein , per1-interacting protein

GENE ID SPECIES
465770 Pan troglodytes
480996 Canis lupus familiaris
693850 Macaca mulatta
100124524 Bos taurus
100343091 Oryctolagus cuniculus
100398354 Callithrix jacchus
100458896 Pongo abelii
100469716 Ailuropoda melanoleuca
9737 Homo sapiens
67298 Mus musculus
171407 Rattus norvegicus
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