G Protein-Coupled Receptor, Family C, Group 5, Member A Proteins (GPRC5A)

GPRC5A encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. Additionally we are shipping GPRC5A Antibodies (121) and GPRC5A Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPRC5A 9052 Q8NFJ5
GPRC5A 232431  
Rat GPRC5A GPRC5A 312790  
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Top GPRC5A Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
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HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$491.43
Details

GPRC5A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) Interaction Partners

Human G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) interaction partners

  1. Data show that G protein-coupled receptor (show ADRA1A Proteins), family C, group 5, member A (show CXCL14 Proteins) protein (GPRC5A) regulates oxidative stress through vanin 1 (show VNN1 Proteins) protein (VNN1 (show VNN1 Proteins)).

  2. Suppression of GPRC5a results in decreased cell growth, proliferation and migration in pancreatic cancer cell lines via a STAT3 (show STAT3 Proteins) modulated pathway, independent from ERK (show EPHB2 Proteins) activation

  3. our results implicate GPRC5A as a tumor suppressor in breast cancer cells, and GPRC5A exerts its tumor-suppressive function by inhibiting EGFR (show EGFR Proteins) and its downstream pathway

  4. elevated levels of GPRC5A played significant roles in gastric cancer progression

  5. Results show how GPRC5A deficiency leads to dysregulated EGFR (show EGFR Proteins) and STAT3 (show STAT3 Proteins) signaling and lung tumorigenesis.

  6. EGFR (show EGFR Proteins) interacted with GPRC5A and phosphorylated it in two conserved double-tyrosine motifs, Y317/Y320 and Y347/ Y350, at the C-terminal tail of GPRC5A.

  7. The interaction of miR (show MLXIP Proteins)-103a-3p with each of the two 5' UTR targets reduces the expression levels of both GPRC5A mRNA and GPRC5A protein in one normal epithelial and two pancreatic cancer cell lines.

  8. RAI3 may contribute to the malignant progression of hepatocellular carcinoma

  9. Data indicate that in mammary tumors, the mRNA expression of GPRC5A significantly correlated with that of BRCA1.

  10. Decreased GPRC5A expression is associated with non-small cell lung cancers and lung inflammation.

Mouse (Murine) G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A) interaction partners

  1. Data show that G protein-coupled receptor (show GPR34 Proteins), family C, group 5, member A (show CXCL14 Proteins) protein (Gprc5a) deficiency exacerbates the silica-induced tissue damages and fibrogenic response in lungs.

  2. Gprc5a deficiency leads to impaired induction of peripherally derived regulatory T-cells and increased experimental autoimmune encephalomyelitis severity.

  3. Gprc5a deficiency confers susceptibility to endotoxin-induced pulmonary edema and injury, mainly through NF-kappaB (show NFKB1 Proteins) signaling in bronchioalveolar epithelium of lung.

  4. Results show how GPRC5A deficiency leads to dysregulated EGFR (show EGFR Proteins) and STAT3 (show STAT3 Proteins) signaling and lung tumorigenesis.

  5. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 (show STAT3 Proteins) signaling induced by autocrine leukemia inhibitory factor (show LIF Proteins).

  6. Loss of GPRC5A is associated with lung adenocarcinomas.

  7. Gprc5a loss enhances NF-kappaB (show NFKB1 Proteins) activation in lung epithelial cells

  8. analysis of the Rai3 gene promoter revealed that the proximal region harbors most of the elements necessary for its regulation, including GC boxes and Sp1 (show SP1 Proteins)-, AP1 (show JUN Proteins)-, and AP2 (show TFAP2A Proteins)-binding sites, and a retinoic acid response element

  9. Data show that targeted inactivation of Raig1 did not cause significant developmental defects, and tha epithelial cell differentiation was normal and lung structure was intact.

GPRC5A Protein Profile

Protein Summary

This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.

Gene names and symbols associated with GPRC5A

  • G protein-coupled receptor, family C, group 5, member A (GPRC5A)
  • G protein-coupled receptor, family C, group 5, member A (Gprc5a)
  • G protein-coupled receptor, family C, group 5, member A-like (LOC100349493)
  • retinoic acid-induced protein 3-like (LOC100624186)
  • GPCR5A protein
  • Rai3 protein
  • Raig1 protein

Protein level used designations for GPRC5A

G-protein coupled receptor family C group 5 member A , RAIG-1 , orphan G-protein-coupling receptor PEIG-1 , retinoic acid induced 3 , retinoic acid responsive , retinoic acid-induced gene 1 protein , retinoic acid-induced protein 3

GENE ID SPECIES
9052 Homo sapiens
232431 Mus musculus
312790 Rattus norvegicus
516026 Bos taurus
486680 Canis lupus familiaris
417960 Gallus gallus
100730088 Cavia porcellus
101110748 Ovis aries
100349493 Oryctolagus cuniculus
100624186 Sus scrofa
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