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Orphan receptor.. Additionally we are shipping GPR142 Proteins (5) and many more products for this protein.
Showing 10 out of 50 products:
Human Polyclonal GPR142 Primary Antibody for EIA, WB - ABIN952600
Matsuo, Matsumoto, Nagano, Masumoto, Takasaki, Matsumoto, Kobori, Katoh, Shigeyoshi: Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system. in Biochemical and biophysical research communications 2005
Show all 3 references for 952600
Human Polyclonal GPR142 Primary Antibody for ELISA, WB - ABIN449715
Süsens, Hermans-Borgmeyer, Urny, Schaller: Characterisation and differential expression of two very closely related G-protein-coupled receptors, GPR139 and GPR142, in mouse tissue and during mouse development. in Neuropharmacology 2006
e developed GPR142 agonists as insulin secretagogues. In this report, we show the discovery of a selective, potent small-molecule GPR142 antagonist, CLP-3094, and its pharmacological characteristics. These data support targeting this receptor for the treatment of chronic inflammatory diseases.
these findings demonstrate GPR142 is a Tryptophan receptor critically required for insulin (show INS Antibodies) and incretin hormone (show GIP Antibodies) regulation and suggest GPR142 agonists may be effective therapies that leverage amino acid sensing pathways for the treatment of type 2 diabetes.
GPR142 mRNA showed a ubiquitous expression both in the brain and in various peripheral glands and organs in pre- and postnatal development.
G protein-coupled receptor 142
, kinesin family member 19
, probable G-protein coupled receptor 142
, G-protein coupled receptor PGR2
, G protein-coupled receptor PGR2