anti-G Protein-Coupled Receptor 17 (GPR17) Antibodies

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Additionally we are shipping GPR17 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR17 2840 Q13304
GPR17 574402 Q6NS65
GPR17 767613 Q09QM4
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Top anti-GPR17 Antibodies at antibodies-online.com

Showing 10 out of 98 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IHC (p) Immunocytochemistry/Immunofluorescence: GPR17 Antibody [NLS4229] - immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells. Immunohistochemistry-Paraffin: GPR17 Antibody [NLS4229] - IHC staining of human brain, neurons and glia. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of HeLa cells, using GPR17 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: GPR17 Antibody [NBP1-51988] - Staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: GPR17 Antibody [NBP1-51988] - NBP1-51988 (0.1ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram) using GPR17 Antibody . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in brain tissue (formalin-fixed, paraffin-embedded) using GPR17 Antibody , followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GPR17 antibody  for IHC. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p) Brain, Neurons and glia Cells expressing target protein - immunostained with target.,.antibody 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from LOVO cells, using GPR17 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GPR17 Antibody (Center) (ABIN653809) in MDA-MB435 cell line lysates (35 µg/lane). GPR17 (arrow) was detected using the purified polyclonal antibody. GPR17 Antibody (Center) (ABIN653809) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Goat Un-conjugated IHC (p), ELISA, WB Anti-GPR17 antibody IHC staining of human heart, desmosomes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101834 concentration 10 ug/ml. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated WB Western blot analysis of GPR17 expression in HEK293T (A), Jurkat (B), NIH3T3 (C), rat kidney (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details

GPR17 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GPR17 Antibodies

  1. Human Polyclonal GPR17 Primary Antibody for ICC, IHC (p) - ABIN271042 : Ciana, Fumagalli, Trincavelli, Verderio, Rosa, Lecca, Ferrario, Parravicini, Capra, Gelosa, Guerrini, Belcredito, Cimino, Sironi, Tremoli, Rovati, Martini, Abbracchio: The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. in The EMBO journal 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GPR17 Primary Antibody for ELISA, WB - ABIN4315679 : Parravicini, Ranghino, Abbracchio, Fantucci: GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. in BMC bioinformatics 2008 (PubMed)

More Antibodies against GPR17 Interaction Partners

Human G Protein-Coupled Receptor 17 (GPR17) interaction partners

  1. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  2. GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.

  3. This review summarizes knowledge about role of GPR17 receptors in physiology and pathology of nervous system, with special attention to remyelination processes.

  4. Low levels of GRK2 (show ADRBK1 Antibodies)/GRK5 (show GRK5 Antibodies) causes a slow and not complete desensitization/down-regulation of GPR17.

  5. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (show GPRC5D Antibodies) GPR17.

  6. Data validate GPR17 as a target for neurorepair

  7. Nucleotides, nucleotide sugars, and cysteinyl leukotrienes do not promote activation of GPR17 in five different cell lines, nor does GPR17 have signaling properties.

  8. analysis of agonist-induced trafficking of native GPR17 in oligodendroglial cells

  9. A functional cross-talk exists between cysteinyl-leukotriene and purinergic sites at GPR17; the latter have a hierarchy in producing desensitizing signals.

  10. We present the first isoform-specific characterization of GPR17 and show that differences exist between the isoforms in expression pattern and pharmacological profile; the two human isoforms might serve tissue-specific functions

Mouse (Murine) G Protein-Coupled Receptor 17 (GPR17) interaction partners

  1. The loss of Gpr17 in mice led to precocious myelination and an earlier onset of remyelination after demyelination

  2. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  3. GPR17(+) cells--in contrast to GPR17(-) NG2 (show Vcan Antibodies)-glia--did not differentiate within 3 months, a peculiarity that was overcome after cerebral damage induced by acute injury or ischemia

  4. stimulation of GPR17 by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP Antibodies) expression levels mainly by triggering the Galphai/o signaling pathway.

  5. Agrp (show AGRP Antibodies)-Gpr17(-/-) mice show reduced food intake, increased relative energy expenditure, and increased satiety, resulting in leanness and reduced body fat. They also show increased central nervous system sensitivity to insulin (show INS Antibodies) and leptin (show LEP Antibodies).

  6. The mouse GPR17 receptor plays a central role in the early response of cardiac stromal cells to ischaemia.

  7. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (show GPRC5C Antibodies) GPR17.

  8. GPR17 is a marker for progenitor progression within the oligodendroglial lineage that participates in postacute reactivity of NG2 (show Vcan Antibodies)-proteoglycan (show Vcan Antibodies) expressing cells in different injury paradigms.

  9. CysLT1R (show CYSLTR1 Antibodies), CysLT2R (show CYSLTR2 Antibodies) and GPR17 might be involved in the MPTP (show PTPN2 Antibodies)-induced Parkinson disease damage in mice.

  10. analysis of agonist-induced trafficking of native GPR17 in oligodendroglial cells

GPR17 Antigen Profile

Protein Summary

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

Gene names and symbols associated with GPR17

  • G protein-coupled receptor 17 (GPR17) antibody
  • G protein-coupled receptor 17 (Gpr17) antibody
  • AI853548 antibody
  • GPR17 antibody

Protein level used designations for GPR17

G protein-coupled receptor 17 , uracil nucleotide/cysteinyl leukotriene receptor-like , uracil nucleotide/cysteinyl leukotriene receptor , G-protein coupled receptor 17 , P2Y-like receptor , R12 , UDP/CysLT receptor

GENE ID SPECIES
699576 Macaca mulatta
769024 Gallus gallus
100444185 Pongo abelii
100593986 Nomascus leucogenys
100611956 Pan troglodytes
782442 Bos taurus
2840 Homo sapiens
574402 Mus musculus
767613 Rattus norvegicus
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