G Protein-Coupled Receptor 17 (GPR17) ELISA Kits

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Additionally we are shipping GPR17 Antibodies (97) and GPR17 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GPR17 GPR17 2840 Q13304
Anti-Mouse GPR17 GPR17 574402 Q6NS65
Anti-Rat GPR17 GPR17 767613 Q09QM4
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More ELISA Kits for GPR17 Interaction Partners

Human G Protein-Coupled Receptor 17 (GPR17) interaction partners

  1. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  2. GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.

  3. This review summarizes knowledge about role of GPR17 receptors in physiology and pathology of nervous system, with special attention to remyelination processes.

  4. Low levels of GRK2 (show ADRBK1 ELISA Kits)/GRK5 (show GRK5 ELISA Kits) causes a slow and not complete desensitization/down-regulation of GPR17.

  5. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (show GPRC5D ELISA Kits) GPR17.

  6. Data validate GPR17 as a target for neurorepair

  7. Nucleotides, nucleotide sugars, and cysteinyl leukotrienes do not promote activation of GPR17 in five different cell lines, nor does GPR17 have signaling properties.

  8. analysis of agonist-induced trafficking of native GPR17 in oligodendroglial cells

  9. A functional cross-talk exists between cysteinyl-leukotriene and purinergic sites at GPR17; the latter have a hierarchy in producing desensitizing signals.

  10. We present the first isoform-specific characterization of GPR17 and show that differences exist between the isoforms in expression pattern and pharmacological profile; the two human isoforms might serve tissue-specific functions

Mouse (Murine) G Protein-Coupled Receptor 17 (GPR17) interaction partners

  1. The loss of Gpr17 in mice led to precocious myelination and an earlier onset of remyelination after demyelination

  2. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  3. GPR17(+) cells--in contrast to GPR17(-) NG2 (show Vcan ELISA Kits)-glia--did not differentiate within 3 months, a peculiarity that was overcome after cerebral damage induced by acute injury or ischemia

  4. stimulation of GPR17 by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (show MBP ELISA Kits) expression levels mainly by triggering the Galphai/o signaling pathway.

  5. Agrp (show AGRP ELISA Kits)-Gpr17(-/-) mice show reduced food intake, increased relative energy expenditure, and increased satiety, resulting in leanness and reduced body fat. They also show increased central nervous system sensitivity to insulin (show INS ELISA Kits) and leptin (show LEP ELISA Kits).

  6. The mouse GPR17 receptor plays a central role in the early response of cardiac stromal cells to ischaemia.

  7. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (show GPRC5C ELISA Kits) GPR17.

  8. GPR17 is a marker for progenitor progression within the oligodendroglial lineage that participates in postacute reactivity of NG2 (show Vcan ELISA Kits)-proteoglycan (show Vcan ELISA Kits) expressing cells in different injury paradigms.

  9. CysLT1R (show CYSLTR1 ELISA Kits), CysLT2R (show CYSLTR2 ELISA Kits) and GPR17 might be involved in the MPTP (show PTPN2 ELISA Kits)-induced Parkinson disease damage in mice.

  10. analysis of agonist-induced trafficking of native GPR17 in oligodendroglial cells

GPR17 Antigen Profile

Antigen Summary

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

Gene names and symbols associated with GPR17

  • G protein-coupled receptor 17 (GPR17) antibody
  • G protein-coupled receptor 17 (Gpr17) antibody
  • AI853548 antibody
  • GPR17 antibody

Protein level used designations for GPR17

G protein-coupled receptor 17 , uracil nucleotide/cysteinyl leukotriene receptor-like , uracil nucleotide/cysteinyl leukotriene receptor , G-protein coupled receptor 17 , P2Y-like receptor , R12 , UDP/CysLT receptor

GENE ID SPECIES
699576 Macaca mulatta
769024 Gallus gallus
100444185 Pongo abelii
100593986 Nomascus leucogenys
100611956 Pan troglodytes
782442 Bos taurus
2840 Homo sapiens
574402 Mus musculus
767613 Rattus norvegicus
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