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GPR56 encodes a member of the G protein-coupled receptor family. Additionally we are shipping GPR56 Antibodies (58) and GPR56 Proteins (8) and many more products for this protein.
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Gpr56 regulates oligodendrocyte development via interactions with Galpha12 (show GNA12 ELISA Kits)/13 and RhoA (show RHOA ELISA Kits)
Functional relevance of GPR56 expression (show HOXA9 ELISA Kits)was va (show MEIS1 ELISA Kits)lidated in m (show RUNX1 ELISA Kits)ice, in which co-expression of Gpr56 significantly accelerated HOXA9-induced leukemogenesis
expression and activation of GPR56 may modulate melanoma progression in part by inducing IL-6 (show IL6 ELISA Kits) production after N-terminal fragment dissociation and C-terminal fragment self-activation
Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor (show ADRA1A ELISA Kits) G1 (ADGRG1; GPR56) differentially regulate downstream signaling
GPR56 regulates the proliferation and invasion capacity of osteosarcoma cells.
High GPR56 expression was significantly associated with high-risk genetic subgroups and poor outcome in patients with acute myeloid leukemia (show BCL11A ELISA Kits) and identifies cancer stem cells with high repopulating potential.
Data suggest that agonist-induced signal transduction via either GPR56/ADGRG1 or BAI1 (show BAI1 ELISA Kits)/ADGRB1 does not require conserved membrane-proximal stalk region of these proteins; ADGRG1 may participate in stalk-dependent and stalk-independent signaling.
Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells
we knocked down GPR56 in cardiomyocytes and found that GPR56 promoted Ang II (show AGT ELISA Kits)-induced cardiomyocyte hypertrophy and it contributed to PCBP2 (show PCBP2 ELISA Kits) effects on cardiomyocyte hypertrophy
GPR56 and GPR110 are activated by exposure of a cryptic tethered agonist
These findings demonstrate that reduced expression of GPR56 in lung fibroblasts may be an important link with pulmonary fibrosis, playing a role in regulating some important fibroblast functions.
determine the crystal structure of the GPR56 extracellular domain.
knockdown of Gpr56 delayed onset of HOXA9 (show HOXA9 ELISA Kits)/MEIS1 (show MEIS1 ELISA Kits)-induced AML (show RUNX1 ELISA Kits)
GPR56 is a cell-autonomous regulator of oligodendrocyte development
Although GPR56 is abundantly and selectively expressed by primitive HSPCs, its high level expression is largely dispensable for steady-state and regenerative hematopoiesis.
Data show that Gpr56, a G-coupled protein receptor, is required for hematopoietic cluster formation during transdifferentiation process in endothelial to hematopoietic cell transition (EHT (show CBFA2T2 ELISA Kits)).
These data illustrate a signaling pathway through GPR56 which regulates muscle hypertrophy associated with resistance/loading-type exercise.
adhesion G protein-coupled receptor (show GPR34 ELISA Kits) GPR56-mediated RhoA (show RHOA ELISA Kits) activation induced by collagen III stimulation
Role for TG2 (show TGM2 ELISA Kits) in GPR56-mediated melanoma inhibition. The uncovered antagonistic relationship between GPR56 and TG2 (show TGM2 ELISA Kits) proposes a mechanism by which extracellular matrix accumulation/crosslinking in tumors may be reversed.
This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
G protein-coupled receptor 56
, G-protein coupled receptor 56-like
, 7-transmembrane protein with no EGF-like N-terminal domains-1
, G-protein coupled receptor 56
, secretin receptor
, serpentine receptor cyt28