You are viewing an incomplete version of our website. Please click to reload the website as full version.

G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) Proteins (GPSM1)

G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. Additionally we are shipping G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) Antibodies (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPSM1 26086 Q86YR5
GPSM1 246254 Q9R080
GPSM1 67839 Q6IR34
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,956.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GPSM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) (GPSM1) Interaction Partners

Human G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) (GPSM1) interaction partners

  1. Activator of G-protein Signaling 3 is an important regulator of esophageal squamous cell carcinoma proliferation

  2. Results confirmed that Ric-8A (show RIC8A Proteins) can directly bind to AGS3S but failed to facilitate Galpha (show SUCLG1 Proteins)(i)-induced suppression of adenylyl cyclase, suggesting that it may not serve as a guanine exchange factor for AGS3/Galpha (show SUCLG1 Proteins)(i/o)-GDP complex in a cellular environment.

  3. High GPSM1 gene methylation is associated with gastric tumor aggressiveness.

  4. Data identified three new loci for type 2 diabetes with genome-wide significance: MIR129-LEP (show LEP Proteins), GPSM1 and SLC16A13 (show SLC16A13 Proteins).

  5. Our data indicate that decreased expression of AGS3 is correlated with reduced levels of p-CREB (show CREB1 Proteins) in the apoptotic model. The negative role of AGS3 in cell apoptosis was further confirmed by knocking down AGS3.

  6. these results indicate that GRK6 (show GRK6 Proteins) complexes with AGS3-Galphai2 (show GNAI2 Proteins) to regulate CXCR2 (show CXCR2 Proteins)-mediated leukocyte functions at different levels, including downstream effector activation, receptor trafficking, and expression at the cell membrane.

  7. These results provide mechanistic insights into how reversible modulation of Galpha(i3) activity by AGS3 and GIV maintains the delicate equilibrium between promotion and inhibition of autophagy.

  8. AGS3 receptor coupling to both Galphabetagamma and GPR (show ALDH18A1 Proteins)-Galpha (show SUCLG1 Proteins)(i) offer additional flexibility for systems to respond and adapt to challenges and orchestrate complex behaviors

  9. unlike wild-type AGS3, over-expression of an AGS3 mutant lacking this modification fails to enhance macroautophagic activity. These observations imply that AGS3 phosphorylation may participate in the modulation of macroautophagy

  10. These data present AGS3, G-proteins, and mInsc as candidate proteins involved in regulating cellular stress associated with protein-processing pathologies.

Mouse (Murine) G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) (GPSM1) interaction partners

  1. We conclude that LPS (show TLR4 Proteins) priming increases AGS3 levels, which enhances lysosomal function and increases the capacity of macrophages to eliminate intracellular pathogens.

  2. level of basal autophagy, autophagic induction, autophagic flux, autophagic degradation and the anti-autophagic action in macrophages that lacked Galphai3 (show GNAI3 Proteins), AGS3, or RGS19 (show RGS19 Proteins); or had been treated with pertussis toxin, were similar to controls

  3. AGS3 has a role in the regulation of G-protein signaling in the immune system

  4. these results indicate that GRK6 (show GRK6 Proteins) complexes with AGS3-Galphai2 (show GNAI2 Proteins) to regulate CXCR2 (show CXCR2 Proteins)-mediated leukocyte functions at different levels, including downstream effector activation, receptor trafficking, and expression at the cell membrane.

  5. The present study demonstrates an important role for GPSM1 in controlling the dynamics of cyst progression in an orthologous mouse model of autosomal dominant polycystic kidney disease.

  6. These data suggest that Gpsm1 acts through a novel receptor-independent mechanism to facilitate renal tubular epithelial cell proliferation and renal tubular regeneration.

  7. AGS3 null mice exhibited a lean phenotype, reduced fat mass, and increased nocturnal energy expenditure.

  8. The GPR (show ALDH18A1 Proteins) motif in this protein and other proteins is actually associated with activity as a GDI - guanine nucleotide dissociation inhibitor and not GTPase (show RACGAP1 Proteins) activator as initially suggested.

G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) (GPSM1) Protein Profile

Protein Summary

G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GPSM1

  • G-protein signaling modulator 1 (GPSM1)
  • G-protein signaling modulator 1 (Gpsm1)
  • G-protein signalling modulator 1 (AGS3-like, C. elegans) (Gpsm1)
  • 1810037C22Rik protein
  • Ags3 protein
  • AW107933 protein

Protein level used designations for GPSM1

G-protein signalling modulator 1 (AGS3-like, C. elegans) , G-protein-signaling modulator 1 , activator of G-protein signaling 3 , G-protein signaling modulator 1 (AGS3-like, C. elegans)

GENE ID SPECIES
26086 Homo sapiens
246254 Rattus norvegicus
67839 Mus musculus
Selected quality suppliers for G-Protein Signaling Modulator 1 (AGS3-Like, C. Elegans) Proteins (GPSM1)
Did you look for something else?