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G1 To S Phase Transition 1 Proteins (GSPT1)

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Additionally we are shipping GSPT1 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSPT1 2935 P15170
GSPT1 14852 Q8R050
Rat GSPT1 GSPT1 24420  
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Top GSPT1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GSPT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for G1 To S Phase Transition 1 (GSPT1) Interaction Partners

Human G1 To S Phase Transition 1 (GSPT1) interaction partners

  1. GAB2 (show GAB2 Proteins), GSPT1, TFDP2 (show TFDP2 Proteins) and ZFPM1 (show ZFPM1 Proteins) are four new susceptibility loci for testicular germ cell tumor.

  2. The survivin and eRF3 complex may function in spindle formation and segregation of chromosomes and cytokinesis.

  3. Overexpression of ID1 (show ID1 Proteins) in two different cell lines induced STMN3 (show STMN3 Proteins) and GSPT1 at the transcriptional level, while depletion of ID1 (show ID1 Proteins) reduced their expression.

  4. The proteolytic cleavage of eRF3a and eRF3b into p-eRF3 leads to release an amino-terminal fragment containing nuclear export signal to allow the relocalization of eRF3 into the nucleus to interact with the p14ARF.

  5. ERF3 is targeted for caspase (show CASP3 Proteins)-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis.

  6. Our results show that the presence of the longer allele of eRF3a is correlated with threefold increased risk of breast cancer development

  7. A biological role for the overlapping ERF3 PAM2 motifs in the regulation of deadenylase accessibility to PABPC1 (show PABPC1 Proteins) at the 3' end of poly(A).

  8. crystal structures of the MLLE domain from PABPC1 in complex with the two PAM2 regions of eRF3

  9. GSPT1/eRF3 is proteolytically processed into an IAP (show ALPI Proteins)-binding protein

  10. Human translation termination factor eRF3/GSPT1 is an interacting partner of RNase L (show RNASEL Proteins).

GSPT1 Protein Profile

Protein Summary

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Gene names and symbols associated with GSPT1

  • G1 to S phase transition 1 (gspt1)
  • G1 to S phase transition 1 (GSPT1)
  • G1 to S phase transition 1 (LOC100218738)
  • G1 to S phase transition 1 (Gspt1)
  • 551G9.2 protein
  • AI314175 protein
  • AI326449 protein
  • AV307676 protein
  • C79774 protein
  • eRF3a protein
  • ETF3A protein
  • G1st protein
  • GSPT1 protein
  • gspt2 protein
  • Gst-1 protein
  • GST1 protein
  • zgc:91975 protein

Protein level used designations for GSPT1

G1 to S phase transition 2 , eukaryotic peptide chain release factor GTP-binding subunit ERF3A , G1 to S phase transition 1 , eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like , G1 to S phase transition protein 1 homolog , eukaryotic peptide chain release factor subunit 3a , G1 to phase transition 1 , G1-to-S transition GTP binding protein , eRF3a , eukaryotic polypeptide chain release factor 3 , guanine nucleotide regulatory protein , G1 to S phase transition protein 1 , G1-to-S phase transition 1

GENE ID SPECIES
446795 Xenopus laevis
479846 Canis lupus familiaris
548522 Xenopus (Silurana) tropicalis
739261 Pan troglodytes
100218738 Taeniopygia guttata
100413998 Callithrix jacchus
100465019 Ailuropoda melanoleuca
100541316 Meleagris gallopavo
100594836 Nomascus leucogenys
2935 Homo sapiens
14852 Mus musculus
24420 Rattus norvegicus
445485 Danio rerio
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