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GATA Binding Protein 4 Proteins (GATA4)

GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Additionally we are shipping GATA4 Antibodies (160) and GATA4 Kits (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GATA4 2626 P43694
GATA4 14463 Q08369
GATA4 54254 P46152
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Top GATA4 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,045.17
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Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,081.83
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,232.17
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$3,237.67
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details

GATA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,
,

More Proteins for GATA Binding Protein 4 (GATA4) Interaction Partners

Xenopus laevis GATA Binding Protein 4 (GATA4) interaction partners

  1. Data show that GATA4 or 6 regulate both cardiogenic potential and subsequent cardiomyocyte differentiation but that GATA5 is involved in regulating cardiomyocyte differentiation.

  2. Results describe the expression of GATA4 and 6 during gastrulation and their function in migratory behaviour.

  3. The data demonstrate that KLF13 (show KLF13 Proteins) is an important component of the transcription network required for heart development and suggest that KLF13 (show KLF13 Proteins) is a GATA-4 modifier

  4. Data show that GATA4 knockdown only affects cardiac marker expression in the absence of either GATA5 or GATA6, suggesting redundancy in this family during myocardial development.

Rabbit GATA Binding Protein 4 (GATA4) interaction partners

  1. These results indicate a higher capacity of adipose-derived than bone marrow-derived mesenchymal stem cells to express GATA4.

Human GATA Binding Protein 4 (GATA4) interaction partners

  1. This study showed that GATA4 gene involved in neuronal growth and cerebellum development and associated with neurological and psychological disorders.

  2. Kaplan-Meier survival analysis revealed significantly shorter overall survival in pediatric Acute myeloid leukemia (show BCL11A Proteins) with GATA4 promoter methylation but multivariate analysis shows that it is not an independent factor.

  3. Data show that the combination of GATA binding protein 4 (Gata4), T-box transcription factor 5 (Tbx5 (show TBX5 Proteins)) and BRG1-associated factor 60C (show SMARCD3 Proteins) protein (Baf60c (show SMARCD3 Proteins)) is sufficient for inducing adipose tissue-derived mesenchymal stem cells (ADMSCs) to form cardiomyocytes.

  4. we identified a mutation in the GATA4 Kozak sequence that likely contributes to the pathogenesis of Atrial septal defect.

  5. Whole exome sequencing results on four-generation Chinese family with atrial septal defect (ASD (show ARSD Proteins)) identified a novel mutation in GATA4 gene at the methylation position associated with ASD (show ARSD Proteins).

  6. this study confirms that GATA4 M310V mutation may lead to the development of the congenital heart defect (show Vcan Proteins), ASD (show ARSD Proteins).

  7. Germline mutations in the NKX2-5 (show NKX2-5 Proteins), GATA4, and CRELD1 (show CRELD1 Proteins) genes do not appear to be associated with CHD (show CHDH Proteins) in Mexican DS patients.

  8. No copy number variations of the gene were detected. GST (show SLCO6A1 Proteins) pull-down assays demonstrated that all potentially deleterious variants, including those previously reported, did not impair the interaction with GATA4

  9. The present study is the first to suggest that GATA-4 gene methylation status may independently predict health status in individuals with COPD (show ARCN1 Proteins).

  10. GATA4 accumulates in multiple tissues, including the aging brain, and could contribute to aging and its associated inflammation.

Pig (Porcine) GATA Binding Protein 4 (GATA4) interaction partners

  1. investigation of genes regulated by GATA4, GATA6 (show GATA6 Proteins), and both in combination: studies in granulosa cells primed for luteinization

  2. GATA-4 and C/EBPbeta (show CEBPB Proteins) are both required for FSH (show BRD2 Proteins) +/- IGF-I (show IGF1 Proteins) stimulation of the porcine steroidogenic acute regulatory protein (show STAR Proteins) gene promoter in homologous granulosa cell cultures.

  3. The altered ratio of GATA4 to GATA6 (show GATA6 Proteins) after ovulation may allow GATA6 (show GATA6 Proteins) to enhance STAR mRNA accumulation.

Mouse (Murine) GATA Binding Protein 4 (GATA4) interaction partners

  1. GATA4 and GATA6 (show GATA6 Proteins) are essential for female fertility, whereas targeting either factor alone causes subfertility. GATA4 and GATA6 (show GATA6 Proteins) are also required for the expression of the receptors for prolactin (show PRL Proteins) and luteinizing hormone.

  2. Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine (show CCL1 Proteins) signaling.

  3. data support the concept that under physiological conditions microbiota stimulate Gata4, which suppresses Asbt (show SLC10A2 Proteins) expression

  4. MITF (show MITF Proteins) interacts with BRG1 (show SMARCA4 Proteins) to promote GATA4 expression in cardiac hypertrophy.

  5. Data show that three transcriptional factors Gata4, Mef2c (show MEF2C Proteins), and Tbx5 (show TBX5 Proteins) (abbreviated as GMT (show GAMT Proteins)) significantly improved murine embryonic stem cells (ESCs (show NR2E3 Proteins)) differentiated into cardiomyocytes.

  6. the data suggest that the inhibitory effects of melatonin on testosterone production are mediated via down-regulation of GATA-4 and SF-1 (show SF1 Proteins) expression.

  7. GATA4/6-mediated inhibition of hedgehog (show SHH Proteins) signaling is a major mechanism regulating pancreatic endoderm specification during patterning of the gut (show GUSB Proteins) tube

  8. GATA4 is required for neonatal heart regeneration through regulation of Fgf16 (show FGF16 Proteins).

  9. Study reports extensive and complex interdependent genomic occupancy of TBX5 (show TBX5 Proteins), NKX2-5 (show NKX2-5 Proteins), and the zinc finger TF GATA4 coordinately controlling cardiac gene expression, differentiation, and morphogenesis.

  10. studies suggest that Gata4 has evolved distinct functions in the development of these tissues that cannot be performed by Gata6 (show GATA6 Proteins), even when it is provided in the identical expression domain

Cow (Bovine) GATA Binding Protein 4 (GATA4) interaction partners

  1. The activity of Gata4 cardiac enhancer in transgenic embryos and in cultured aortic endothelial cells is dependent on four ETS (show ETS1 Proteins) sites.

Zebrafish GATA Binding Protein 4 (GATA4) interaction partners

  1. Study finds that emergent juvenile cortical cardiomyocytes induce expression of gata4 in a manner similar to during regeneration.

  2. ATOH8, GATA4, and FOG2 associate in a single complex

  3. gata4 gene regulates sdf1a (show CXCL12 Proteins) levels during early embryogenesis

  4. mga restricts the normal levels of Gata4 required for heart tube looping.

  5. Through the use of a transgenic reporter strain, we found that cardiomyocytes throughout the subepicardial ventricular layer trigger expression of the embryonic cardiogenesis gene gata4 within a week of trauma

  6. Gata4 and Gata6 (show GATA6 Proteins) have distinct non-redundant functions in cardiac morphogenesis, but are redundant for an early step of liver development; and Gata4 and Gata6 (show GATA6 Proteins) are essential and non-redundant for liver growth following initial budding

  7. Data show that GATA4 knockdown only affects cardiac marker expression in the absence of either GATA5 (show GATA6 Proteins) or GATA6 (show GATA6 Proteins), suggesting redundancy in this family during myocardial development.

  8. Results suggest that GATA4 and -6 play a key role in the regulation of ventricular myosin heavy chain gene expression in the ventricle.

GATA4 Protein Profile

Protein Summary

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

Gene names and symbols associated with GATA Binding Protein 4 Proteins (GATA4)

  • GATA binding protein 4 (LOC100230031)
  • GATA binding protein 4 (gata4)
  • GATA binding protein 4 (GATA4)
  • glutamyl-tRNA(Gln) amidotransferase subunit A (gatA4)
  • GATA-4 zinc-finger transcription factor (GATA-4)
  • gata4 transcription factor (gata4)
  • GATA4 (LOC100534420)
  • GATA binding protein 4 (Gata4)
  • GATA binding protein 4 (gata4-b)
  • GATA-binding protein 4 (gata4)
  • ASD2 protein
  • gata protein
  • Gata-4 protein
  • gata4 protein
  • MGC81427 protein
  • VSD1 protein
  • xGATA-4 protein
  • xgata4 protein

Protein level used designations for GATA Binding Protein 4 Proteins (GATA4)

GATA binding protein 4 , glutamyl-tRNA(Gln) amidotransferase subunit A , GATA-4 zinc-finger transcription factor , gata4 transcription factor , GATA4 , GATA-4 transcription factor , GATA-binding factor 4 , transcription factor GATA-4 , GATA-binding protein 4 , DNA-binding protein GATA-GT2 , transcription factor GATA4 , transcription factor xGATA-4 , xGATA-4

GENE ID SPECIES
100230031 Taeniopygia guttata
443781 Xenopus laevis
472698 Pan troglodytes
549703 Xenopus (Silurana) tropicalis
696775 Macaca mulatta
5809170 Sorangium cellulosum So ce56
100008858 Oryctolagus cuniculus
100329087 Saccoglossus kowalevskii
100534420 Oreochromis niloticus
100602105 Nomascus leucogenys
396392 Gallus gallus
2626 Homo sapiens
486079 Canis lupus familiaris
397555 Sus scrofa
14463 Mus musculus
54254 Rattus norvegicus
327716 Bos taurus
100716226 Cavia porcellus
100820749 Ovis aries
399302 Xenopus laevis
30483 Danio rerio
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