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GATA Binding Protein 6 Proteins (GATA6)

GATA6 is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. Additionally we are shipping GATA6 Antibodies (108) and GATA6 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GATA6 2627 Q92908
GATA6 14465 Q61169
GATA6 29300 P46153
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Top GATA6 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,067.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,265.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,688.67
Details

GATA6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for GATA Binding Protein 6 (GATA6) Interaction Partners

Human GATA Binding Protein 6 (GATA6) interaction partners

  1. GATA6 induces expression of genes essential for growth of colon cancer cells under adherent conditions (REG4 (show REG4 Proteins)) and genes required for their clonogenicity (LGR5 (show LGR5 Proteins)), and miR (show MLXIP Proteins)-363-GATA6-REG4 (show REG4 Proteins)/LGR5 (show LGR5 Proteins) signaling cascade promotes tumorigenicity of colon cancer cells.

  2. In the pancreas, Gata6 acts as a tumour suppressor by enforcing acinar cell differentiation, by directly and indirectly repressing ectopic differentiation programmes, and by regulating crucial cancer-related gene expression pathways.

  3. Our results, for the first time, portray a pivotal role of GATA6 in regulating metastatic behaviors of breast cancer cells

  4. miR (show MLXIP Proteins)-181b was upregulated by hypoxia in retinoblastoma in an HIF-1a (show HIF1A Proteins)-independent manner. Additionally, miR (show MLXIP Proteins)-181b exerts its angiogenic function, at least in part, by inhibiting PDCD10 (show PDCD10 Proteins) and GATA6.

  5. data indicated that GATA-6 and Akt2 (show AKT2 Proteins) are involved in the mTORC1-mediated regulation of VSMC proliferation and differentiation.

  6. results show how genetic mutations in GATA6 may lead to functional inactivity and pancreatic agenesis in humans

  7. GATA6 expression is progressively increased during Barrett's oesophagus development and its malignant transformation to esophageal adenocarcinoma.

  8. KLF5 (show KLF5 Proteins)/GATA4 (show GATA4 Proteins)/GATA6 may promote gastric cancer development by engaging in mutual crosstalk, collaborating to maintain a pro-oncogenic transcriptional regulatory network in gastric cancer cells.

  9. association of GATA6 loss-of-function mutations with enhanced susceptibility to familial dilated cardiomyopathy

  10. These results establish SHP (show LAMC1 Proteins) as a novel antihypertrophic regulator that acts by interfering with GATA6 signaling.

Cow (Bovine) GATA Binding Protein 6 (GATA6) interaction partners

  1. GATA4 (show GATA4 Proteins) and GATA6 mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 showed a marked decrease at the regressed luteal stage, like NR5A1 (show NR5A1 Proteins), NR5A2 (show NR5A2 Proteins), and the other steroidogenic markers.

Mouse (Murine) GATA Binding Protein 6 (GATA6) interaction partners

  1. GATA4 (show GATA4 Proteins) and GATA6 are essential for female fertility, whereas targeting either factor alone causes subfertility. GATA4 (show GATA4 Proteins) and GATA6 are also required for the expression of the receptors for prolactin (show PRL Proteins) and luteinizing hormone.

  2. GATA4 (show GATA4 Proteins)/6-mediated inhibition of hedgehog (show SHH Proteins) signaling is a major mechanism regulating pancreatic endoderm specification during patterning of the gut (show GUSB Proteins) tube

  3. In the pancreas, Gata6 acts as a tumour suppressor by enforcing acinar cell differentiation, by directly and indirectly repressing ectopic differentiation programmes, and by regulating crucial cancer-related gene expression pathways.

  4. The role of GATA4 (show GATA4 Proteins) in the regulation of cardiomyocyte maturation in the newborn heart and in maintaining diastolic function in the adult heart.

  5. Our results, for the first time, portray a pivotal role of GATA6 in regulating metastatic behaviors of breast cancer cells

  6. data indicated that GATA-6 and Akt2 (show AKT2 Proteins) are involved in the mTORC1-mediated regulation of VSMC proliferation and differentiation.

  7. GATA6 contributes to the development and postnatal function of the murine atrioventricular node by promoting cell-cycle exit of specified cardiomyocytes toward a conduction system lineage.

  8. Gata6 is a versatile and potent reprograming factor that can act alone to drive a cell fate switch from diverse cell types

  9. Mice with double deletion of Gata4 (show GATA4 Proteins) and Gata6 lack identifiable adrenal glands. Inactivation of Gata6 alone drastically reduced the adrenal size and corticosterone production in the adult animals.

  10. GATA6 likely regulates enteroendocrine cell differentiation cell autonomously whereas GATA4 (show GATA4 Proteins) affects this population indirectly

Zebrafish GATA Binding Protein 6 (GATA6) interaction partners

  1. these data suggest an essential role for Pak1 (show PAK1 Proteins) as an Erk (show MAPK1 Proteins) activator, and Gata6 as an Erk (show MAPK1 Proteins) target, during neural crest development.

  2. specification of cardiac fate downstream of gata5/6 involves activation of the tmem88a gene to constrain WNT (show WNT2 Proteins) signaling and expand the number of cardiac progenitors.

  3. in zebrafish the gata6 genes are redundant for specification of cardiomyocytes.

  4. Results suggest that GATA4 and -6 play a key role in the regulation of ventricular myosin heavy chain gene expression in the ventricle.

Pig (Porcine) GATA Binding Protein 6 (GATA6) interaction partners

  1. investigation of genes regulated by GATA6, GATA4 (show GATA4 Proteins), and both in combination: studies in granulosa cells primed for luteinization

  2. The altered ratio of GATA4 (show GATA4 Proteins) to GATA6 after ovulation may allow GATA6 to enhance STAR mRNA accumulation.

GATA6 Protein Profile

Protein Summary

This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects.

Gene names and symbols associated with GATA Binding Protein 6 Proteins (GATA6)

  • GATA binding protein 6 (gata6)
  • GATA binding protein 6 (GATA6)
  • GATA binding protein 6 (LOC100228783)
  • GATA binding protein 6 (Gata6)
  • GATA-binding protein 6 (gata6)
  • transcription factor GATA-6 (GATA-6)
  • AA410133 protein
  • cb603 protein
  • GATA-5 protein
  • GATA-6 protein
  • gata6 protein
  • gata6a protein
  • gata6b protein
  • pnr protein
  • tGata6 protein
  • XGATA-6 protein
  • XGATA6 protein

Protein level used designations for GATA Binding Protein 6 Proteins (GATA6)

zinc-finger transcription factor Gata6 , GATA binding protein 6 , transcription factor GATA-6-like , GATA-binding factor 6 , transcription factor GATA-6 , GATA-6 transcription factor , GATA-6 , GATA-binding protein 6 , DNA-binding protein GATA-GT2

GENE ID SPECIES
395062 Xenopus (Silurana) tropicalis
431694 Canis lupus familiaris
100228783 Taeniopygia guttata
100434852 Pongo abelii
2627 Homo sapiens
396390 Gallus gallus
654400 Bos taurus
14465 Mus musculus
29300 Rattus norvegicus
490520 Canis lupus familiaris
58076 Danio rerio
397600 Sus scrofa
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