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anti-GM2 Ganglioside Activator (GM2A) Antibodies

GM2A encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Additionally we are shipping GM2 Ganglioside Activator Proteins (12) and GM2 Ganglioside Activator Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GM2A 282838  
GM2A 2760 P17900
GM2A 14667 Q60648
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Top anti-GM2 Ganglioside Activator Antibodies at antibodies-online.com

Showing 10 out of 132 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GM2A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate WB Suggested Anti-GM2A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB GM2A Antibody (N-term) (ABIN652023) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the GM2A antibody detected the GM2A protein (arrow). GM2A Antibody (N-term) (ABIN652023) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the GM2A antibody detected the GM2A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated EIA, WB HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human GM2A with DYKDDDDK tag probed with AP23748PU-N (1.0 µg/ml) in Lane A and probed with anti-DYKDDDDK Tag (1/30000) in Lane C. Mock-transfected HEK293 probed with AP23748PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Staining of Rat Kidney lysate using GM2A Antibody at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Goat Un-conjugated EIA, WB HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human GM2A with DYKDDDDK tag probed with AP23749PU-N (1.0 µg/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/30000) in Lane C. Mock-transfected HEK293 probed with AP23749PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Staining of Rat Kidney lysate using GM2A antibody at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-GM2A antibody  ABIN1048677 IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GM2A antibody  ABIN1048677 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

GM2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


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Mouse (Murine)
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More Antibodies against GM2 Ganglioside Activator Interaction Partners

Human GM2 Ganglioside Activator (GM2A) interaction partners

  1. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies

  2. Gene polymorphisms of MD2 (show LY96 Antibodies) and GM2A were associated with the occurrence or severity of neonatal necrotizing enterocolitis.

  3. In vitro assays with the isolated H1 or H2 homodimers (beta-alpha hybrid construct of beta-hexosaminidase A subunits) confirmed that neither was capable of human GM2AP-dependent hydrolysis of GM2 (show CYB5D2 Antibodies) ganglioside.

  4. impact of GM2AP on glucose metabolism

  5. Treatment of meniscal explants with IL-1RA (show IL1RN Antibodies) inhibited the expression of many catabolic genes following a single bout of high dynamic strain.

  6. these results provide novel insights into the physiological functions of GM2AP in obesity.

  7. GM2 (show CYB5D2 Antibodies) activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

  8. Two new structures of GM2-AP with bound lipids, showing two different lipid-binding modes within the apolar pocket

  9. elucidation of mode of action on gangioside GM2 (show CYB5D2 Antibodies)

  10. alpha-subunit loop structure is required for GM2 activator protein binding by beta-hexosaminidase A

Mouse (Murine) GM2 Ganglioside Activator (GM2A) interaction partners

  1. impact of GM2AP on glucose metabolism

  2. these results provide novel insights into the physiological functions of GM2AP in obesity.

  3. GM2 (show CYB5D2 Antibodies) activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

  4. The trafficking of prosaposin (show PSAP Antibodies) and GM2 (show CYB5D2 Antibodies) activator protein to the lysosome in sertoli cells is dependent on sortilin (show SORT1 Antibodies).

GM2 Ganglioside Activator (GM2A) Antigen Profile

Protein Summary

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GM2A

  • GM2 ganglioside activator (Gm2a) antibody
  • GM2 ganglioside activator (GM2A) antibody
  • GM2 ganglioside activator (gm2a) antibody
  • GM2 ganglioside activator protein (Gm2a) antibody
  • AA408702 antibody
  • AW215435 antibody
  • fb96e04 antibody
  • fb96e10 antibody
  • GM2-AP antibody
  • GM2A antibody
  • MGC84154 antibody
  • SAP-3 antibody
  • wu:fb96e04 antibody
  • wu:fb96e10 antibody
  • zgc:110188 antibody

Protein level used designations for GM2A

GM2 ganglioside activator protein , ganglioside GM2 activator , GM2 ganglioside activator , GM2 activator protein , cerebroside sulfate activator protein , shingolipid activator protein 3 , sphingolipid activator protein 3

GENE ID SPECIES
282838 Rattus norvegicus
471705 Pan troglodytes
479324 Canis lupus familiaris
504524 Bos taurus
548463 Xenopus (Silurana) tropicalis
550529 Danio rerio
779153 Xenopus laevis
100174922 Felis catus
2760 Homo sapiens
14667 Mus musculus
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