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Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. Additionally we are shipping GPI Anchor Attachment Protein 1 Proteins (6) and GPI Anchor Attachment Protein 1 Kits (2) and many more products for this protein.
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Human Polyclonal GPAA1 Primary Antibody for EIA, IHC (p) - ABIN952582
Ho, Cheung, Patil, Chen, Fan: Increased expression of glycosyl-phosphatidylinositol anchor attachment protein 1 (GPAA1) is associated with gene amplification in hepatocellular carcinoma. in International journal of cancer. Journal international du cancer 2006
Show all 3 references for ABIN952582
Cow (Bovine) Polyclonal GPAA1 Primary Antibody for IHC, WB - ABIN2782597
Vainauskas, Menon: Endoplasmic reticulum localization of Gaa1 and PIG-T, subunits of the glycosylphosphatidylinositol transamidase complex. in The Journal of biological chemistry 2005
the lumenal domain of GAA1/GPAA1 has a 3D structure similar to that of an M28-type aminopeptidase (show CPQ Antibodies). GAA1/GPAA1 is a candidate for the enzyme that catalyzes the peptide bond formation between the omega-site and a phosphoethanolamine group of GPI (show GNPDA1 Antibodies) lipid anchor.
a conserved proline in the last transmembrane segment of Gaa1 is required for glycosylphosphatidylinositol recognition by GPI transamidase
Increased expression of glycosyl-phosphatidylinositol anchor attachment protein 1 is associated with gene amplification in hepatocellular carcinoma
Results show an increased expression level and elevated copy number for GAA1 in head and neck squamous carcinoma, suggesting a role for this GPI (show GNPDA1 Antibodies) anchor subunit in HNSCC.
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains.
GAA1 protein homolog
, GPAA1P anchor attachment protein 1 homolog
, GPI anchor attachment protein 1
, GPI transamidase subunit
, anchor attachment protein 1 (Gaa1p, yeast) homolog
, glycophosphatidylinositol anchor attachment 1
, glycosylphosphatidylinositol anchor attachment 1 protein
, glycosylphosphatidylinositol anchor attachment protein 1 homolog
, anchor attachment protein 1
, glycosylphosphatidylinositol anchor attachment 1 (GPAA1)