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GRB2-Associated Binding Protein 3 Proteins (GAB3)

GAB3 is a member of the GRB2-associated binding protein gene family. Additionally we are shipping GAB3 Antibodies (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GAB3 139716 Q8WWW8
GAB3 210710 Q8BSM5
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Top GAB3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

GAB3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for GRB2-Associated Binding Protein 3 (GAB3) Interaction Partners

Human GRB2-Associated Binding Protein 3 (GAB3) interaction partners

  1. The carboxy-terminal SH3 domain of the adapter prot (show GRAP2 Proteins)ein Mona interacts with the atypical proline-rich domain of Gab3 to mediate late signaling of the macrophage colony-stimulating factor receptor.

  2. Hematopoiesis in mice lacking Gab3 is not impaired, macrophages develop in normal numbers and exhibit normal function, and there is no major immune deficiency in T- and B-lymphocyte responses to protein antigens or during viral infection.

Mouse (Murine) GRB2-Associated Binding Protein 3 (GAB3) interaction partners

  1. Induced expression and association of the Mona/Gads (show GRAP2 Proteins) adapter and Gab3 scaffolding protein during monocyte/macrophage differentiation. (Gab3 scaffolding protein)

  2. Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent

GAB3 Protein Profile

Protein Summary

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GAB3

  • GRB2-associated binding protein 3 (GAB3)
  • GRB2-associated binding protein 3 (gab3)
  • growth factor receptor bound protein 2-associated protein 3 (Gab3)
  • 5930433H21Rik protein

Protein level used designations for GAB3

GRB2-associated binding protein 3 , GRB2-associated-binding protein 3 , growth factor receptor bound protein 2-associated protein 3 , DOS/Gab family member 3 , GRB2-associated binder 3 , Gab3 scaffolding protein

GENE ID SPECIES
428717 Gallus gallus
473837 Pan troglodytes
701859 Macaca mulatta
100063152 Equus caballus
100328766 Oryctolagus cuniculus
100453438 Pongo abelii
100474423 Ailuropoda melanoleuca
100554434 Anolis carolinensis
100603503 Nomascus leucogenys
139716 Homo sapiens
492262 Canis lupus familiaris
100518409 Sus scrofa
512009 Bos taurus
210710 Mus musculus
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