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GRB2-Related Adaptor Protein (GRAP) ELISA Kits

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. Additionally we are shipping GRAP Antibodies (52) and GRAP Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
Anti-Rat GRAP GRAP 363616  
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Top GRAP ELISA Kits at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

More ELISA Kits for GRAP Interaction Partners

Human GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed a (show TGFB1 ELISA Kits)s a novel component of TGF-beta signaling in cultured human renal tubule cells.

  2. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  3. Our findings define a pathway involving CD28 (show CD28 ELISA Kits) binding to Grb-2 (show GRB2 ELISA Kits) and its co-operativity with Vav1 (show VAV1 ELISA Kits) in the regulation of T-cell co-stimulation.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) interaction partners

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta (show TGFB1 ELISA Kits)-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2 (show GRB2 ELISA Kits), acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk (show EPHB2 ELISA Kits) pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 domain-containing adapters Grb2 (show GRB2 ELISA Kits) and Grap

GRAP Antigen Profile

Antigen Summary

This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Gene names and symbols associated with GRAP

  • GRB2-related adaptor protein (GRAP) antibody
  • GRB2-related adaptor protein a (grapa) antibody
  • zgc:109892 (zgc:109892) antibody
  • GRB2-related adaptor protein (Grap) antibody
  • 8430435N19Rik antibody
  • BB233594 antibody
  • grap antibody
  • MGC109892 antibody
  • si:dkeyp-9d4.1 antibody
  • zgc:110202 antibody

Protein level used designations for GRAP

GRB2-related adaptor protein , GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein

GENE ID SPECIES
416523 Gallus gallus
489534 Canis lupus familiaris
553596 Danio rerio
555184 Danio rerio
10750 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
534491 Bos taurus
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