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The protein encoded by GEM belongs to the RAD/GEM family of GTP-binding proteins. Additionally we are shipping GEM Kits (6) and GEM Proteins (5) and many more products for this protein.
Showing 10 out of 57 products:
Human Polyclonal GEM Primary Antibody for ICC, IF - ABIN4313837
Laurberg, Jensen, Schepeler, Borre, Ørntoft, Dyrskjøt: High expression of GEM and EDNRA is associated with metastasis and poor outcome in patients with advanced bladder cancer. in BMC cancer 2014
Show all 2 references for ABIN4313837
Chicken Polyclonal GEM Primary Antibody for IHC, WB - ABIN2775304
Kelly: The RGK family: a regulatory tail of small GTP-binding proteins. in Trends in cell biology 2005
Human Polyclonal GEM Primary Antibody for ELISA, WB - ABIN4313839
Wang, Johnston, Chou, Dean: A systemic network for Chlamydia pneumoniae entry into human cells. in Journal of bacteriology 2010
Rad (show RRAD Antibodies), Gem and Rem (show REM1 Antibodies) all reduce depolarization-dependent Ca2 (show CA2 Antibodies)+ entry in developing myotubes.
These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.
Mechanism of the inhibition of calcium channel activity by Gem.
docking of the RGK protein to the nucleotide-kinase domain of the Cavbeta subunit is reminiscent of the binding of GMP (show NT5C2 Antibodies) to guanylate kinase (show GUK1 Antibodies)
Results identify specific nuclear localization signals (NLS (show ALDH1A2 Antibodies)) in Kir/Gem that are both required and sufficient for nuclear transport.
Down regulation of Gem expression was involved in the pathogenesis of hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and it might be a favorable independent prognostic parameter for HCC (show FAM126A Antibodies).
These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages.
Gem is involved both in T-cell spontaneous cell migration as well as chemotaxis and plays an important role in cell-to-cell HTLV-1 viral transmission.
Data show a mechanism by which GTPase Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9.
Gem contains two candidate inhibitory sites, each capable of producing full inhibition of P/Q-type Ca(2 (show CA2 Antibodies)+) channels.
GEM plays a key role during C. pneumoniae entry into human cells.
We discuss the structural and functional properties of RGK proteins and highlight recent work addressing the mechanism of Gem regulation by calmodulin (show CALM1 Antibodies) and 14-3-3 (show YWHAQ Antibodies).
crystallographic structure and biochemical characterization indicate that Gem G-domain markedly prefers GDP over GTP (show AK3 Antibodies)
Gem is a bona fide GTPase (show RACGAP1 Antibodies) that exhibits striking structural and biochemical features that should impact its regulation and cellular activities
The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Ras-related associated with diabetes
, GTP binding protein overexpressed in skeletal muscle
, GTP binding protein gene overexpressed in skeletal muscle
, GTP-binding protein GEM
, GTP-binding mitogen-induced T-cell protein
, RAS-like protein KIR
, GTP binding protein (gene overexpressed in skeletal muscle)
, Gem GTPase
, GTP-binding protein overexpressed in skeletal muscle
, kinase-inducible Ras-like protein