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anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) Antibodies

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. Additionally we are shipping GCHFR Proteins (8) and GCHFR Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GCHFR 2644 P30047
GCHFR 320415 P99025
GCHFR 171128 P70552
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Top anti-GCHFR Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using GCHFR Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB GCHFR Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GCHFR antibody detected the GCHFR protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot analysis of GCHFR expression in transfected 293T cell line by GCHFR MaxPab polyclonal antibody.Lane 1: GCHFR transfected lysate(9.70 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IF, ELISA Detection limit for recombinant GST tagged GCHFR is approximately 0.03ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to GCHFR on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details

GCHFR Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-GCHFR Antibodies

  1. Cow (Bovine) Polyclonal GCHFR Primary Antibody for WB - ABIN2781329 : Ohta, Funayama, Ichinose, Toyoshima, Urano, Matsuo, Tomoko, Yukihiko, Yoshino, Yokoyama, Shimazu, Maeda, Hasegawa, Obata: Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia. in Archives of neurology 2006 (PubMed)

  2. Human Polyclonal GCHFR Primary Antibody for WB - ABIN515984 : Du, Teng, Lawrence, Guan, Xu, Ge, Shi: The protein partners of GTP cyclohydrolase I in rat organs. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal GCHFR Primary Antibody for IHC, ELISA - ABIN1534956 : Hochstrasser, Frutiger, Paquet, Bairoch, Ravier, Pasquali, Sanchez, Tissot, Bjellqvist, Vargas: Human liver protein map: a reference database established by microsequencing and gel comparison. in Electrophoresis 1993 (PubMed)

More Antibodies against GCHFR Interaction Partners

Human GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response.

  2. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (show GCH1 Antibodies) by its phosphorylation and interplay with GFRP.

  3. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein

  4. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling

  5. GFRP/GTPCHI (show GCH1 Antibodies) axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus.

  6. GCH1 (show GCH1 Antibodies) mutations in Japanese patients with DYT5 (show GCH1 Antibodies) dystonia. In some of them, the GCH1 (show GCH1 Antibodies) enzyme activity was proved to be impaired.

  7. The co-expression of GTP cyclohydrolase I (show GCH1 Antibodies) (GCHI) with tyrosine hydroxylase (TH (show TH Antibodies)) indicates that TH is indeed active in human neurosecretory neurons.

  8. Demonstrate role for GFRP in regulating iNOS (show NOS2 Antibodies)-mediated NO synthesis and suggest that the allosteric regulation of GTP (show AK3 Antibodies)-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo.

  9. 6BH(4) de novo synthesis is controlled by H(2)O(2) in a concentration-dependent manner, but H(2)O(2)-mediated oxidation does not affect the functionality of the GTPCHI (show GCH1 Antibodies)/GFRP complex.

Mouse (Murine) GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (show GCH1 Antibodies) by its phosphorylation and interplay with GFRP (show NR4A1 Antibodies).

  2. GTPCH (show GCH1 Antibodies) expression is the primary regulator of BH4 levels, and changes in GTPCH (show GCH1 Antibodies) or BH4 are not necessarily accompanied by changes in GFRP (show NR4A1 Antibodies) expression.

GCHFR Antigen Profile

Protein Summary

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

Gene names and symbols associated with GCHFR

  • GTP cyclohydrolase I feedback regulator (LOC100220034) antibody
  • GTP cyclohydrolase I feedback regulator (GCHFR) antibody
  • GTP cyclohydrolase I feedback regulator (Gchfr) antibody
  • 2010323F13Rik antibody
  • GFRP antibody
  • HsT16933 antibody
  • P35 antibody

Protein level used designations for GCHFR

GTP cyclohydrolase I feedback regulator , GTP cyclohydrolase 1 feedback regulatory protein , GTP cyclohydrolase I feedback regulatory protein , GFRP , p35

GENE ID SPECIES
100220034 Taeniopygia guttata
2644 Homo sapiens
617650 Bos taurus
320415 Mus musculus
171128 Rattus norvegicus
423003 Gallus gallus
100153745 Sus scrofa
Selected quality suppliers for anti-GCHFR (GCHFR) Antibodies
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