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GTPase, IMAP Family Member 5 Proteins (GIMAP5)

GIMAP5 encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. Additionally we are shipping GTPase, IMAP Family Member 5 Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GIMAP5 55340 Q96F15
GIMAP5 317757 Q8BWF2
GIMAP5 246774 Q8K3L6
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Top GTPase, IMAP Family Member 5 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,786.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$486.07
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GIMAP5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for GTPase, IMAP Family Member 5 (GIMAP5) Interaction Partners

Human GTPase, IMAP Family Member 5 (GIMAP5) interaction partners

  1. gimap5 has a role in maintaining peripheral tolerance and T cell homeostasis in the gut (show GUSB Proteins) [review]

  2. Data indicate that overexpression of GTPase (show RACGAP1 Proteins) of the immune-associated nucleotide (show GIMAP8 Proteins)-binding protein (show COASY Proteins) 5 (show CAPS Proteins) (GIMAP5) in HEK (show EPHA3 Proteins) (human embryonic kidney)-293 cells resulted in increased Ca2 (show CA2 Proteins)+ accumulation within the mitochondria.

  3. Notch (show NOTCH1 Proteins) signalling protects T-ALL cells from apoptosis by upregulating the expression of GIMAP5.

  4. These data establish Gimap5 as a key regulator of hematopoietic integrity and lymphocyte homeostasis

  5. A significant increase in systemic lupus erythematosus risk associated with the most common GIMAP5 haplotype was found (odds ratio 1.26, 95% CI 1.02 to 1.54, p = 0.0033).

  6. Resutls show that Gimap5 is located in the endoplasmic reticulum, and the endogenous Gimap5 mRNA is up-regulated in activated T-cells.

  7. These data suggest that the GIMAP5 gene is associated with islet autoimmunity in type I diabetes and add to recent findings implicating the same single nucleotide polymorphism in another autoimmune disease.

  8. Data show that IAN5 polymorphisms are associated with susceptibility to Systemic lupus erythematosus and the development of clinical disease manifestations in a strictly Korean population.

Mouse (Murine) GTPase, IMAP Family Member 5 (GIMAP5) interaction partners

  1. functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.

  2. gimap5 has a role in maintaining peripheral tolerance and T cell homeostasis in the gut (show GUSB Proteins) [review]

  3. The defects in T-cell cellularity were more severe in mice lacking both Gimap3 and Gimap5.

  4. a novel link between Gimap5 and Foxo (show FOXO3 Proteins) expression and provide evidence for a regulatory mechanism that controls Foxo (show FOXO3 Proteins) protein expression and may help to maintain immunological tolerance.

  5. Gimap5 is an important stabilizer of mouse hematopoietic progenitor cell survival.

  6. mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT (show CTSL1 Proteins)-cell development, and the maintenance of normal liver function

GTPase, IMAP Family Member 5 (GIMAP5) Protein Profile

Protein Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Gene names and symbols associated with GIMAP5

  • GTPase, IMAP family member 5 (GIMAP5)
  • GTPase, IMAP family member 2 (GIMAP2)
  • GTPase, IMAP family member 5 (Gimap5)
  • D630024P16 protein
  • E230026N22Rik protein
  • GIMAP5 protein
  • HIMAP3 protein
  • IAN-5 protein
  • IAN4 protein
  • Ian4l1 protein
  • Ian5 protein
  • IMAP3 protein
  • IROD protein

Protein level used designations for GIMAP5

GTPase, IMAP family member 5 , GTPase IMAP family member 5 , immune associated nucleotide 4 like 1 , immunity associated protein 3 , immunity-associated nucleotide 5 protein , inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5 , immunity-associated nucleotide 4-like 1 protein , immunity-associated protein 3 , IAN-4 , immunity-associated nucleotide 4 protein

GENE ID SPECIES
420413 Gallus gallus
463896 Pan troglodytes
482797 Canis lupus familiaris
505013 Bos taurus
55340 Homo sapiens
317757 Mus musculus
246774 Rattus norvegicus
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