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anti-GTPase Activating Protein (GAP) Antibodies

may play a role in Ras GTPase mediated signal transduction\\\\; may be involved in cell proliferation and cell migration [RGD, Feb 2006].. Additionally we are shipping GTPase Activating Protein Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAP 29127 Q9H0H5
GAP 25676 P50904
GAP 218397  
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Top anti-GTPase Activating Protein Antibodies at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from COS7 cells, using GTPase Activating Protein (Phospho-Ser387) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta, using GTPase Activating Protein (Phospho-Ser387) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from COS7 cells, using GTPase Activating Protein (Ab-387) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using GTPase Activating Protein (Ab-387) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IF, IHC, WB 100 μg Log in to see 9 to 14 Days
$346.19
Details
Human Rabbit Un-conjugated ICC, IF, WB 100 μg Log in to see 9 to 14 Days
$346.19
Details
Human Sheep Un-conjugated IP, WB   250 μg Log in to see 11 to 16 Days
$485.57
Details

GAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,

Rat (Rattus)


Mouse (Murine)


Top referenced anti-GTPase Activating Protein Antibodies

  1. Human Polyclonal GAP Primary Antibody for IF, IHC - ABIN1531650 : Kawashima, Hirose, Satoh, Kaneko, Ikeda, Kaziro, Nosaka, Kitamura: MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells. in Blood 2000 (PubMed)

More Antibodies against GTPase Activating Protein Interaction Partners

Human GTPase Activating Protein (GAP) interaction partners

  1. No significant association between SNPs of RGS6 (show RGS6 Antibodies) and central adiposity has been found.

  2. RacGAP1 (show RACGAP1 Antibodies) Is a Novel Downstream Effector of E2F7 (show E2F7 Antibodies)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma

  3. RACGAP1 (show RACGAP1 Antibodies) expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.

  4. reduced RGS6 (show RGS6 Antibodies) expression is associated with poor survival in colorectal cancer patients, suggesting that RGS6 (show RGS6 Antibodies) expression may serve as an important prognostic marker

  5. central spindle assembly and 2 Plk1 (show PLK1 Antibodies)-dependent phosphorylations are required to establish efficient binding of the Ect2 (show ECT2 Antibodies) BRCT in early cytokinesis.

  6. RacGAP1 (show RACGAP1 Antibodies) expression at the invasive front in gastric cancer was significantly correlated with factors reflecting tumor progression and poor prognosis.RACGAP1 gene expression in diffuse type gastric cancer was elevated.

  7. RacGAP1 mediated endothelial barrier function loss and melanoma transmigration in a focal adhesion-dependent manner.RacGAP1 activation mediates focal adhesion assembly and actin stress fiber formation.

  8. High RacGAP1 (show RACGAP1 Antibodies) expression was an independent predictive marker for lymph node metastasis, recurrence and poor prognosis in colorectal cancer patients.

  9. these date demonstrate that RGS6 (show RGS6 Antibodies) decreases in tumor tissue and may serve as a novel biomarker for outcomes in pancreatic cancer patients and be a potential therapeutic target potential therapeutic target.

  10. HCV viral protein NS5B polymerase activity was significantly reduced by silencing RacGAP1 (show RACGAP1 Antibodies) and, vice versa, was increased by overexpression of RacGAP1 (show RACGAP1 Antibodies) in a cell-based reporter assay.

Mouse (Murine) GTPase Activating Protein (GAP) interaction partners

  1. Double-deficient RASA1 (show RASA1 Antibodies)-neurofibromin 1 (show NF1 Antibodies) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (show NOTCH1 Antibodies) gene.

  2. Rasa1 (show RASA1 Antibodies) may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  3. Regulation of Rasa1 (show RASA1 Antibodies) translation by miR (show MLXIP Antibodies)-132 was seen in severed axons, demonstrating local function within the axon.

  4. RASA1 (show RASA1 Antibodies) mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS (show RASA1 Antibodies) subject and in the animal model.

  5. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 (show D4S234E Antibodies) GTPase activating protein (show RASA1 Antibodies) 1 (RASA1 (show RASA1 Antibodies))

  6. 14-3-3 (show YWHAQ Antibodies) negatively regulates the RGC downstream of the PI3-kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway

  7. Caspase-3 (show CASP3 Antibodies) is a stress intensity sensor that controls cell fate by either initiating a RasGAP (show RASA1 Antibodies) cleavage-dependent cell resistance program or a cell suicide response mediated by akt (show AKT1 Antibodies).

  8. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

  9. Ca2 (show CA2 Antibodies)+-dependent monomer and dimer formation switches CAPRI (show RASA4 Antibodies) Protein between Ras GTPase-activating protein (show RASA1 Antibodies) (GAP) and RapGAP (show RAP1GAP Antibodies) activities

  10. statins inhibit GGPP biosynthesis in the mevalonate pathway, and then inhibit signal transduction in the Ras/ERK (show EPHB2 Antibodies) and Ras/Akt (show AKT1 Antibodies) pathways, thereby inhibiting bFGF (show FGF2 Antibodies), HGF (show HGF Antibodies), TGF-beta (show TGFB1 Antibodies) expression

GTPase Activating Protein (GAP) Antigen Profile

Protein Summary

This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.

Gene names and symbols associated with GAP

  • Rac GTPase activating protein 1 (RACGAP1) antibody
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) antibody
  • RAS p21 protein activator 1 (Rasa1) antibody
  • regulator of G-protein signaling 6 (RGS6) antibody
  • CYK4 antibody
  • GAP antibody
  • GAPX antibody
  • HsCYK-4 antibody
  • ID-GAP antibody
  • MgcRacGAP antibody
  • Rasa antibody
  • RasGAP antibody

Protein level used designations for GAP

GTPase activating protein , male germ cell RacGap , protein CYK4 homolg , protein CYK4 homolog , rac GTPase-activating protein 1 , GAP , GTPase-activating protein , RAS p21 protein activator 1 , p120GAP , ras GTPase-activating protein 1 , rasGAP , p120-rasGAP , H_DJ1108A12.1 , S914 , WUGSC:H_DJ0283M22.1 , WUGSC:H_DJ1108A12.1 , regulator of G-protein signalling 6

GENE ID SPECIES
29127 Homo sapiens
25676 Rattus norvegicus
218397 Mus musculus
9628 Homo sapiens
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