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Galactosamine (N-Acetyl)-6-Sulfate Sulfatase Proteins (GALNS)

GALNS encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Additionally we are shipping Galactosamine (N-Acetyl)-6-Sulfate Sulfatase Antibodies (93) and Galactosamine (N-Acetyl)-6-Sulfate Sulfatase Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GALNS 2588 P34059
GALNS 50917 Q571E4
GALNS 292073 Q32KJ6
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Top Galactosamine (N-Acetyl)-6-Sulfate Sulfatase Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$827.20
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,408.17
Details

GALNS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus) ,
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More Proteins for Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) Interaction Partners

Human Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) interaction partners

  1. A new GALNS intronic lesion was characterized: c.245-11C>G causing m-RNA defects, although identified outside the GT/AG splice pair.

  2. The goals were to analyze and characterize the secondary structure, regions of intrinsic disorder and physicochemical characteristics of three classes of mutations described in the enzyme N-acetylgalactosamine-6-sulfatase.

  3. A review of mutations in the GALNS gene associated with Morquio A syndrome.

  4. Molecular analysis of 163 patients with Morquio A identified 99 unique mutations in the GALNS gene believed to negatively impact GALNS protein function.

  5. Here we present 53 mutations including 19 novel mutations in GALNS gene in a cohort of 55 patients

  6. GALNS gene 5 new mutations: p.N177S, p.G290R, p.F306S, p.W520X, p.W403_T404delinsCS in the mucopolysaccharidosis IVA patients in South China

  7. Novel mutations in the GALNS gene associated with mucopolysaccharidosis IVA in Korean patients.

  8. missense mutation in GALNS is associated with a severe form of mucopolysaccharidosis type IVA.

  9. Comparison of the structure of GALNS to paralogous sulfatases shows a wide variety of active-site geometries in the family but strict conservation of the catalytic machinery

  10. Screening of mutations and polymorphisms in GALNS gene provide useful information on genotype/phenotype correlations.

Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) Protein Profile

Protein Summary

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

Gene names and symbols associated with GALNS

  • N-acetylgalactosamine-6-sulfatase (Plabr_0892)
  • N-acetylgalactosamine-6-sulfatase (Plabr_1680)
  • N-acetylgalactosamine-6-sulfatase (Plabr_2744)
  • N-acetylgalactosamine-6-sulfatase (Plabr_3133)
  • N-acetylgalactosamine-6-sulfatase (Plabr_3297)
  • N-acetylgalactosamine-6-sulfatase (Plabr_3918)
  • N-acetylgalactosamine-6-sulfatase (Plabr_3935)
  • N-acetylgalactosamine-6-sulfatase (Plabr_4057)
  • N-acetylgalactosamine-6-sulfatase (Plabr_4157)
  • N-acetylgalactosamine-6-sulfatase (Plabr_4160)
  • N-acetylgalactosamine-6-sulfatase (Plabr_4308)
  • N-acetylgalactosamine-6-sulfatase (Plabr_4647)
  • N-acetylgalactosamine-6-sulfatase (Celly_0425)
  • N-acetylgalactosamine-6-sulfatase (Halhy_0527)
  • N-acetylgalactosamine-6-sulfatase (Halhy_2233)
  • N-acetylgalactosamine-6-sulfatase (Halhy_4972)
  • galactosamine (N-acetyl)-6-sulfate sulfatase (GALNS)
  • galactosamine (N-acetyl)-6-sulfate sulfatase (Galns)
  • GalN6S protein
  • GALNAC6S protein
  • GAS protein
  • mFLJ00319 protein
  • MPS4A protein

Protein level used designations for GALNS

N-acetylgalactosamine-6-sulfatase , N-acetylgalactosamine-6-sulfate sulfatase , chondroitinase , chondroitinsulfatase , galNAc6S sulfatase , galactose-6-sulfate sulfatase , GalNAc6S sulfatase , galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA)

GENE ID SPECIES
10238283 Planctomyces brasiliensis DSM 5305
10239081 Planctomyces brasiliensis DSM 5305
10240157 Planctomyces brasiliensis DSM 5305
10240550 Planctomyces brasiliensis DSM 5305
10240714 Planctomyces brasiliensis DSM 5305
10241341 Planctomyces brasiliensis DSM 5305
10241358 Planctomyces brasiliensis DSM 5305
10241480 Planctomyces brasiliensis DSM 5305
10241580 Planctomyces brasiliensis DSM 5305
10241583 Planctomyces brasiliensis DSM 5305
10241731 Planctomyces brasiliensis DSM 5305
10242078 Planctomyces brasiliensis DSM 5305
10262416 Cellulophaga lytica DSM 7489
10584684 Haliscomenobacter hydrossis DSM 1100
10586401 Haliscomenobacter hydrossis DSM 1100
10589168 Haliscomenobacter hydrossis DSM 1100
2588 Homo sapiens
50917 Mus musculus
292073 Rattus norvegicus
489661 Canis lupus familiaris
397000 Sus scrofa
515809 Bos taurus
415848 Gallus gallus
100732880 Cavia porcellus
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