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Galactosidase, beta 1 Proteins (GLB1)

GLB1 encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Additionally we are shipping GLB1 Antibodies (304) and GLB1 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GLB1 2720 P16278
GLB1 12091 P23780
GLB1 316033  
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Top GLB1 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) REACT_Escherichia coli Un-conjugated   1000 units Log in to see 7 to 9 Days
$237.69
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$423.50
Details
Please inquire Un-conjugated   1 mg Log in to see 2 to 3 Days
$123.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.1 mg Log in to see 6 to 11 Days
$435.71
Details
HOST_Escherichia coli (E. coli) REACT_Escherichia coli Un-conjugated   10 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Escherichia coli (E. coli) General Un-conjugated   100 μg Log in to see 3 to 4 Days
$360.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$841.86
Details

GLB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Galactosidase, beta 1 (GLB1) Interaction Partners

Fruit Fly (Drosophila melanogaster) Galactosidase, beta 1 (GLB1) interaction partners

  1. Functional loss of glucocerebrosidase (show GBA Proteins) or beta-Gal promotes toxic conversion of alphaSyn via aberrant interactions between alphaSyn and their substrate glycolipids, leading to aggravation of alphaSyn-mediated neurodegeneration.

Human Galactosidase, beta 1 (GLB1) interaction partners

  1. This study shows that moderate widespread expression of betagal in the CNS of GM1 gangliosidosis mice is sufficient to achieve significant biochemical impact with phenotypic amelioration and extension in lifespan

  2. The study proposes an explanation for ELNR1 uncoupling based on the age-related alterations of Neu-1 (show NEU1 Proteins) activity.

  3. Overexpression of the novel senescence marker GLB1 in prostate cancer predicts reduced recurrence of PSA (show PLAG1 Proteins)-expressing tumors.

  4. Identification and analysis of GLB1 mutations in Indian patients with GM1 gangliosidosis.

  5. We observed significant lower values of beta-galactosidase, FUC and tendency to decrease of MAN and GLU (show DCTN1 Proteins) concentration in nasal polyps

  6. This study analyzed patient cells with GM1 gangliosidosis and sialidosis. A novel mutation p.E186A is identified in GLB1 gene.

  7. The activity of serum GAL (show GAL Proteins) was significantly higher in colon cancer patients with a history of alcohol and nicotine dependence.

  8. beta-galactosidase, considered as a senescence marker, is over-expressed only in specific subtypes of pituitary adenomas, but is also present in carcinomas considered as a group

  9. In the serum of patients with Lyme disease, GAL (show GAL Proteins) activity significantly increased (p = 0.029), and the activity of FUC had a tendency to increase (p = 0.153), compared to the control group.

  10. In a Turkish population, mutations in GLB1 gene leads to severely deficient enzyme activity and result in infantile phenotype of the GM1 gangliosidosis.

Mouse (Murine) Galactosidase, beta 1 (GLB1) interaction partners

  1. This study shows that moderate widespread expression of betagal in the CNS of GM1 gangliosidosis mice is sufficient to achieve significant biochemical impact with phenotypic amelioration and extension in lifespan

  2. Senescence-associated beta-galactosidase is present in apical vacuoles of visceral endoderm in developing mouse embryos.

  3. We show here that mouse GLB1 has greater stability when compared to human GLB1, and that human GLB1 activity is temperature and protective-dependent on protein cathepsin A (show CTSA Proteins), while that of mouse GLB1 is not

GLB1 Protein Profile

Protein Summary

This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Galactosidase, beta 1 Proteins (GLB1)

  • beta-galactosidase-like (LOC100056371)
  • beta-galactosidase-like (LOC100624593)
  • beta galactosidase (Gal)
  • galactosidase, beta 1 (glb1)
  • galactosidase, beta 1 (GLB1)
  • beta-D-galactosidase (lacZ)
  • beta-D-galactosidase (VV2_1327)
  • beta-D-galactosidase (SSP0105)
  • beta-D-galactosidase (lacH)
  • beta-D-galactosidase (ECL_03691)
  • galactosidase, beta 1 (Glb1)
  • AW125515 protein
  • beta-gal protein
  • beta-Gal-1 protein
  • BGAL protein
  • Bge protein
  • Bgl protein
  • Bgl-e protein
  • Bgl-s protein
  • Bgl-t protein
  • Bgs protein
  • Bgt protein
  • C130097A14Rik protein
  • CG9092 protein
  • Dmel\\CG9092 protein
  • EBP protein
  • ECK0341 protein
  • ELNR1 protein
  • gal protein
  • JW0335 protein
  • lacZ-1 protein
  • MPS4B protein
  • zgc:110823 protein

Protein level used designations for Galactosidase, beta 1 Proteins (GLB1)

CG9092-PA , CG9092-PB , Gal-PA , Gal-PB , beta-galactosidase-1 , beta-galactosidase , acid beta-galactosidase , lactase , beta-D-galactosidase , elastin receptor 1, 67kDa , beta-galactosidase complex , beta-galactosidase electrophoretic , beta-galactosidase systemic regulator , beta-galactosidase temporal , lysosomal beta-galactosidase

GENE ID SPECIES
100056371 Equus caballus
100624593 Sus scrofa
33839 Drosophila melanogaster
548343 Danio rerio
100173272 Pongo abelii
914499 Escherichia coli O157:H7 str. Sakai
945006 Escherichia coli str. K-12 substr. MG1655
957271 Escherichia coli O157:H7 str. EDL933
1036228 Escherichia coli CFT073
1115654 Lactococcus lactis subsp. lactis Il1403
1174493 Yersinia pestis CO92
1181271 Vibrio vulnificus CMCP6
2766512 Yersinia pestis biovar Microtus str. 91001
2955932 Yersinia pseudotuberculosis IP 32953
3120206 Photobacterium profundum SS9
3616165 Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
3994393 Escherichia coli UTI89
4191778 Escherichia coli 536
4714238 Yersinia enterocolitica subsp. enterocolitica 8081
5110958 Enterobacter sp. 638
5581703 Citrobacter koseri ATCC BAA-895
5589745 Escherichia coli E24377A
5593986 Escherichia coli HS
6257657 Yersinia pseudotuberculosis PB1/+
6299686 Erwinia tasmaniensis Et1/99
6383981 Klebsiella pneumoniae
7551563 Staphylococcus carnosus subsp. carnosus TM300
8156216 Escherichia coli 'BL21-Gold(DE3)pLysS AG'
8214972 Escherichia coli O157:H7 str. TW14359
9126168 Enterobacter cloacae subsp. cloacae ATCC 13047
2720 Homo sapiens
12091 Mus musculus
316033 Rattus norvegicus
507188 Bos taurus
493927 Felis catus
403873 Canis lupus familiaris
420720 Gallus gallus
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