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The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Additionally we are shipping Galanin Receptor 1 Kits (21) and and many more products for this protein.
Showing 10 out of 105 products:
Human Polyclonal Galanin Receptor 1 Primary Antibody for EIA, FACS - ABIN952452
Borroto-Escuela, Narvaez, Marcellino, Parrado, Narvaez, Tarakanov, Agnati, Díaz-Cabiale, Fuxe: Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization. in Biochemical and biophysical research communications 2010
Show all 3 references for ABIN952452
Human Polyclonal Galanin Receptor 1 Primary Antibody for FACS, WB - ABIN653295
Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya et al.: Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ... in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009
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Rat (Rattus) Polyclonal Galanin Receptor 1 Primary Antibody for IHC, WB - ABIN1742066
Hawes, Picciotto: Characterization of GalR1, GalR2, and GalR3 immunoreactivity in catecholaminergic nuclei of the mouse brain. in The Journal of comparative neurology 2005
Human Polyclonal Galanin Receptor 1 Primary Antibody for ICC, IHC (p) - ABIN271021
Barson, Chang, Poon, Morganstern, Leibowitz: Galanin and the orexin 2 receptor as possible regulators of enkephalin in the paraventricular nucleus of the hypothalamus: relation to dietary fat. in Neuroscience 2011
Human Polyclonal Galanin Receptor 1 Primary Antibody for ELISA, WB - ABIN190892
Henson, Neubig, Jang, Ogawa, Zhang, Carey, DSilva: Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma. in The Journal of biological chemistry 2005
Human Polyclonal Galanin Receptor 1 Primary Antibody for IF, ELISA - ABIN1535689
Jacoby, Webb, Liu, Kofler, Hort, Fathi, Bottema, Shine, Iismaa: Structural organization of the mouse and human GALR1 galanin receptor genes (Galnr and GALNR) and chromosomal localization of the mouse gene. in Genomics 1998
GAL (show GAL Antibodies) and its receptors, GALR1 and GALR2 (show GALR2 Antibodies), play a role in head and neck squamous cell carcinoma tumorigenesis
Variants in genes for galanin (GAL (show GAL Antibodies)) and its receptors (GALR1, GALR2 (show GALR2 Antibodies), GALR3 (show GALR3 Antibodies)), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who experienced childhood adversity or recent negative life events.
GALR1 methylation is associated with endometrial cancer.
Moreover, we have identified a novel role for the GalR1/galanin (show GAL Antibodies) receptor-ligand axis in chemoresistance, providing evidence to support its further evaluation as a potential therapeutic target and biomarker in colorectal cancer .
Genetic variants in the GALR1 gene are associated with a protective effect in nicotine dependence.
The results of this study suggested an association between variation at the GALR1 locus and baseline craving for tobacco in smokers seeking cessation treatment.
it has been demonstrated that GalR1-5-HT1A (show HTR1A Antibodies) receptors heteromerize.
disregulation of galanin receptor 1 may lead to uncontrolled proliferation and neoplastic transformation
The analyzed single nucleotide polymorphisms in GAL (show GAL Antibodies) and GALR1 do not play major role in early onset obesity or dietary fat intake in obese children and adolescents.
There was no effect of GALR1 on alcoholism risk.
Galanin (show GAL Antibodies), acting via the GAL1 (show LGALS1 Antibodies) receptor and Gi -coupled signalling in L and K cells, is a potent inhibitor of GLP-1 (show GCG Antibodies) and GIP (show GIP Antibodies) secretion
endogenous Gal-1 (show LGALS1 Antibodies) may influence T. cruzi infection by fueling tolerogenic circuits that hinder anti-parasite immunity.
Experiments with a GalR1-preffering galanin (show GAL Antibodies) analog, NAX (show SCN7A Antibodies)-5055, show that GalR1 is involved in regulating glucose and insulin (show INS Antibodies) homeostasis
two different models of chronic pain requires a galanin receptor 1-triggered depression of excitatory synaptic transmission in indirect pathway nucleus accumbens medium spiny neurons.
GalR1 expression is increased in the nucleus accumbens after chronic restraint stress.
Galanin (show GAL Antibodies) opposes the actions of morphine which leads to opiate dependence and withdrawal, an effect that is mediated via GalR1
Galanin receptor 1 deletion exacerbates hippocampal neuronal loss after systemic kainate administration in mice
Rotavirus infection of murine small intestine causes colonic secretion via age restricted galanin (show GAL Antibodies)-1 receptor expression.
Homozygous Galr1-/- mice are viable, capable of breeding, and exhibit no significant difference in growth rate. They have reduced circulating levels of insulin-like growth factor-I (IGF-I (show IGF1 Antibodies)) and exhibit spontaneous tonic-clonic seizures.
The distribution of galanin receptor 1 messenger RNA in the mouse brain is abundantly expressed in many brain regions, including numerous hypothalamic and other forebrain regions associated with neuroendocrine function.
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
galanin receptor 1
, galactose operon repressor
, LacI family transcriptional regulatory protein
, galanin receptor type 1