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Gap Junction Protein, delta 2, 36kDa Proteins (GJD2)

GJD2 encodes a member of the connexin protein family. Additionally we are shipping Gap Junction Protein, delta 2, 36kDa Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GJD2 14617 O54851
Rat GJD2 GJD2 50564 O70610
GJD2 57369 Q9UKL4
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Top Gap Junction Protein, delta 2, 36kDa Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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GJD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Gap Junction Protein, delta 2, 36kDa (GJD2) Interaction Partners

Mouse (Murine) Gap Junction Protein, delta 2, 36kDa (GJD2) interaction partners

  1. The results suggest that electrical synapses formed by Cx36-containing gap junctions occur in most of the widely distributed centers of the auditory system.

  2. The resilts of this study showed that the phosphorylation state of Cx36 as a key biochemical step at the crossroad of light-dark and circadian regulatory pathways that control photoreceptor coupling.

  3. The magnitudes of the 2f1 (show KLRG1 Proteins)-f2 distortion products were not different between Cx36 knockout and wild-type mice, suggesting similar cochlear function in the two groups

  4. Mg(2 (show MCOLN1 Proteins)+)-dependent synaptic plasticity of Cx36-containing electrical synapses could underlie neuronal circuit reconfiguration via changes in brain energy metabolism that affects neuronal levels of intracellular ATP and [Mg(2 (show MCOLN1 Proteins)+)]i.

  5. Gene expression data indicate that EPCs, or their soluble products, modulate the expression of the beta-cell surface molecule connexin 36 and affect glucose-stimulated insulin (show INS Proteins) release in vitro.

  6. Some neurons exhibit at least two discriminatory mechanisms for assembling Cx36 into gap junctions.

  7. The Cx36 was expressed in the mouse carotid body and in the intestine at ileum and colon level.

  8. The results indicate the presence of Cx36-containing gap junctions in the sexually dimorphic dorsomedial nucleus and dorsolateral nucleus of both male and female rodents

  9. The genetic deletion of the GJ subunit Cx36 increased cell survivability by approximately 50% under excitotoxic condition.

  10. Data (including data from studies in knockout mice) suggest that Cx36/Gjd2 gap junction channels are necessary for full up-regulation of insulin (show INS Proteins) secretion by islet cells; mice with defective Cx36/Gjd2 expression exhibit glucose intolerance.

Human Gap Junction Protein, delta 2, 36kDa (GJD2) interaction partners

  1. It was shown that the decreased level of the examined neuronal proteins was accompanied by the impaired coexpression of synaptophysin (show SYP Proteins)/neurofilaments and Cx36 in the series of astrocytomas--anaplastic astrocytomas--glioblastomas.

  2. In this study, there was no association of the analyzed SNPs located in RASGRF1 (show RASGRF1 Proteins). GJD2, and ACTC1 (show ACTC1 Proteins) with pathological myopia.

  3. Three SNP alleles in BRD2 (show BRD2 Proteins), Cx-36, and ME2 and microdeletions in 15q13.3, 15q11.2, and 16p13.11 also contribute risk to juvenile myclonic epilepsy.

  4. Cx36 GJs are highly cation-selective and should exhibit relatively low permeability to numerous vital negatively charged metabolites and high permeability to potassium ion, a major charge carrier in cell-cell communication.

  5. A polymorphism of Cx36 gene is associated to certain forms of human diabetes

  6. connexin genes Gjd2 coding for mCx36, Gjc1 (show GJC1 Proteins) coding for mCx45 and Gja10 coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59) and GJA10 (Cx62 (show GJa10 Proteins)), could be detected at least as transcript isoforms in the human retina.

  7. Variations in GJD2 is associated with refractive errors and myopia.

  8. Mutations in the calcium-binding motifs of CDH23 and the 35delG mutation in GJB2 (show GJB2 Proteins) cause hearing loss in one family

  9. connexin 36 expression is regulated by the transcriptional repressor NRSF/REST

  10. 35delG mutation of the GJB2 (show GJB2 Proteins) gne (show GNE Proteins) is a risk for deafness

Cow (Bovine) Gap Junction Protein, delta 2, 36kDa (GJD2) interaction partners

  1. Interneuronal communication at gap junctions made by connexin 36 may not be regulated by direct phosphorylation of connexin 36, but possibly by phosphorylation of associated proteins.

Gap Junction Protein, delta 2, 36kDa (GJD2) Protein Profile

Protein Summary

This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion.

Gene names and symbols associated with GJD2

  • connexin-36 (CX36)
  • gap junction protein, delta 2, 36kDa (GJD2)
  • gap junction protein, delta 2, 36kDa (LOC100220961)
  • gap junction protein, delta 2, 36kDa (LOC100341036)
  • gap junction protein, delta 2 (Gjd2)
  • connexin36 protein
  • Cx35.1 protein
  • Cx36 protein
  • Gja9 protein
  • GJA10 protein
  • GJD2 protein

Protein level used designations for GJD2

connexin-36 , gap junction protein, alpha 9, 36kDa , gap junction protein, delta 2, 36kDa , gap junction delta-2 protein , gap junction protein, alpha 9, 59kDa , gap junction protein, alpha 10, 62kDa , gap junction alpha-10 protein-like , gap junction alpha-9 protein-like , gap junction alpha-9 protein , gap junction membrane channel protein alpha 9 , gap junction protein, alpha 9 , connexin 36 , connexin 35.1 , gap junction channel-forming protein

GENE ID SPECIES
374170 Gallus gallus
453306 Pan troglodytes
487477 Canis lupus familiaris
697250 Macaca mulatta
704282 Macaca mulatta
715648 Macaca mulatta
100054422 Equus caballus
100065787 Equus caballus
100220961 Taeniopygia guttata
100341036 Oryctolagus cuniculus
100343220 Oryctolagus cuniculus
100446834 Pongo abelii
100453024 Pongo abelii
100601781 Nomascus leucogenys
100603227 Nomascus leucogenys
14617 Mus musculus
50564 Rattus norvegicus
57369 Homo sapiens
282577 Bos taurus
395273 Gallus gallus
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