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Gap Junction Protein, gamma 1, 45kDa Proteins (GJC1)

GJC1 is a member of the connexin gene family. Additionally we are shipping GJC1 Antibodies (79) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat GJC1 GJC1 363677  
GJC1 14615 P28229
GJC1 10052 P36383
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Top GJC1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GJC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Gap Junction Protein, gamma 1, 45kDa (GJC1) Interaction Partners

Mouse (Murine) Gap Junction Protein, gamma 1, 45kDa (GJC1) interaction partners

  1. The ablation of Cx45 reduced neuronal loss by approximately 50% under ischemic insult.

  2. This study demonstrated using Cx45-eGFP transgenic mice that Cx45-eGFP cells are distributed along the rostrocaudal extent of the spinal cord with expression mainly restricted to the grey matter of dorsal laminae I-III

  3. Prostaglandin E stimulates Connexin isoforms via GSK-3beta/beta-catenin (show CTNNB1 Proteins) via EP2-receptor-dependent cAMP/PKA and PI3K/Akt (show AKT1 Proteins) in mouse embryonic stem cells.

  4. Suggest critical role for Cx45 in the regulation of endothelial-induced mesenchymal cell differentiation towards a mural cell phenotype.

  5. Cx45 is required for optimal impulse propagation in the atrioventricular node; cardiomyocyte-directed deficiencies of Cx45 in mice lead to embryonic lethality attributable to morphological and functional cardiovascular defects.

  6. Cx45 is physiologically expressed in vascular smooth muscle

  7. Residual Cx45 and its relationship to Cx43 (show GJA1 Proteins) in murine ventricular myocardium.

  8. The cx45 strongly modulate the firing pattern of individual RGCs, ensuring strongly correlated firing between nearby RGCs and normal patterning of retinogeniculate projections.

  9. Data suggest that Cx45 is expressed on OFF bipolar cell dendrites, presumably forming gap junctions with cells of the same type, and on OFF bipolar cell axon terminals, presumably forming heterologous gap junctions with other retinal neurons.

  10. Data suggest that Cx45 and Cx36 (show GJD2 Proteins) have similar functions in the retina, whereas Cx45 fulfills special functions in the developing heart that cannot be compensated by Cx36 (show GJD2 Proteins).

Human Gap Junction Protein, gamma 1, 45kDa (GJC1) interaction partners

  1. Connexin45 has much more rapid gating kinetics than connexin43 (show GJA1 Proteins)

  2. Results found that the expression of Cx26 (show GJB2 Proteins) and Cx45 had no prognostic value but Cx43 (show GJA1 Proteins) was upregulated in tumour epithelia and membrane Cx43 (show GJA1 Proteins) expression was associated with short overall survival time.

  3. Gap junctional intercellular communication in human bladder smooth muscle cells and suburothelial myofibroblastsdepend of Cx43 (show GJA1 Proteins) rather than on Cx45.

  4. Our data suggest that GJA7 alterations have no or low genetic relevance in nonsyndromic hearing loss in populatins from Turkey, South Africa, United Kingdom, United States, and China.

  5. DNA hypermethylation of the promoter region of GJC1, encoding connexin45, is an important mechanism in silencing gene expression in colorectal cancer.

  6. Study shows that fusion of a V5/6-His tag (hexa (show HEXA Proteins) moiety M r = 0.93 kDa) to the CT segment of Cx40 (show GJA5 Proteins), Cx43 (show GJA1 Proteins) and Cx45 does not prevent the cells from forming channels.

  7. connexin genes Gjd2 (show GJD2 Proteins) coding for mCx36, Gjc1 coding for mCx45 and Gja10 coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59) and GJA10 (Cx62 (show GJa10 Proteins)), could be detected at least as transcript isoforms in the human retina.

  8. Results show that Cx40 (show GJA5 Proteins), Cx37 (show GJA4 Proteins), Cx43 (show GJA1 Proteins) and Cx45 were expressed within the glomeruli.

  9. Studies indicate that 21 different Cxs have been detected and they are generally named according to their approximate molecular mass in Kda, e.g. Cx32 (show GJB1 Proteins), Cx43 (show GJA1 Proteins) and Cx45.

  10. abnormal expression of connexin43 (show GJA1 Proteins) and connexin45 in nasopharynx tissues may be associated with cancerization and squamatization of human nasopharynx tissue

GJC1 Protein Profile

Protein Summary

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described.

Gene names and symbols associated with GJC1

  • gap junction protein, gamma 1, 45kDa (gjc1)
  • gap junction protein, gamma 1, 45kDa (GJC1)
  • gap junction protein, delta 3, 31.9kDa (GJD3)
  • Gap junction gamma-1 protein (gjc1)
  • gap junction protein, delta 3 (Gjd3)
  • gap junction protein, gamma 1 (Gjc1)
  • C130009G16Rik protein
  • Cnx45 protein
  • Cx30.2 protein
  • CX45 protein
  • Gja-7 protein
  • Gja7 protein
  • Gjc1 protein
  • GJD3 protein
  • MGC52735 protein

Protein level used designations for GJC1

gap junction protein, gamma 1, 45kDa , connexin 45 , gap junction protein, alpha 7, 45kDa , gap junction protein, delta 3, 31.9kDa , gap junction membrane channel protein alpha 7 , gap junction gamma-1 protein-like , Gap junction alpha-7 protein , gap junction gamma-1 protein , connexin30.2 , gap junction delta-3 protein , gap junction membrane channel protein chi 1 , connexin-45 , gap junction alpha-7 protein , gap junction channel protein connexin 45 , gap junction protein, alpha 7, 45kDa (connexin 45) , cx45

GENE ID SPECIES
379137 Xenopus laevis
100224659 Taeniopygia guttata
454736 Pan troglodytes
100009380 Oryctolagus cuniculus
100447031 Pongo abelii
100484940 Ailuropoda melanoleuca
100607150 Nomascus leucogenys
379240 Xenopus laevis
363677 Rattus norvegicus
100048959 Sus scrofa
14615 Mus musculus
266706 Rattus norvegicus
10052 Homo sapiens
490936 Canis lupus familiaris
511119 Bos taurus
396501 Gallus gallus
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