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Induces apoptosis.. Additionally we are shipping Gasdermin A Antibodies (26) and many more products for this protein.
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Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation
Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24 (show MED22 Proteins), and PSMD3 (show PSMD3 Proteins) in European continent (EA) subjects.
The GSDMA (rs7212938) and GSDMB (show GSDMB Proteins) (rs7216389) polymorphisms are associated with asthma susceptibility and intermediate asthma phenotypes.
Results suggest an association of 17q21 polymorphisms with ORMDL3 (show ORMDL3 Proteins), GSDMA expression, and IL-17 (show IL17A Proteins) secretion early in life. These observations may imply a functional role of the 17q21 locus affecting T-cell development during immune maturation.
The present data suggest that TGF-beta (show TGFB1 Proteins), LMO1 (show LMO1 Proteins), possibly RUNX3 (show RUNX3 Proteins), and GSDM form a regulatory pathway for directing the pit (show IRF6 Proteins) cells to apoptosis.
Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers.
Evolutionary recombination hotspot around the GSDML (show GSDMB Proteins)-GSDM locus is closely linked to oncogenomic recombination hotspot around the PPP1R1B (show PPP1R1B Proteins)-STARD3 (show STARD3 Proteins)-TCAP (show TCAP Proteins)-PNMT (show PNMT Proteins)-PERLD1 (show PGAP3 Proteins)-ERBB2 (show ERBB2 Proteins)-C17orf37 (show C17orf37 Proteins)-GRB7 (show GRB7 Proteins) amplicon at human chromosome 17q12.
, gasdermin 1
, gasdermin A
, gasdermin A1