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GSDMB encodes a member of the gasdermin-domain containing protein family. Additionally we are shipping Gasdermin B Proteins (3) and many more products for this protein.
Showing 10 out of 47 products:
Human Polyclonal Gasdermin B Primary Antibody for EIA, WB - ABIN453671
Hur, Sung, Shin, Park, Cheong, Bae: TREX1 polymorphisms associated with autoantibodies in patients with systemic lupus erythematosus. in Rheumatology international 2008
Show all 2 references for ABIN453671
Human Polyclonal Gasdermin B Primary Antibody for WB - ABIN2775462
Adams, Leavitt, Holmes: Strabismus surgery for internuclear ophthalmoplegia with exotropia in multiple sclerosis. in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 2009
Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation
GSDMB variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.
The GSDMB-driven HSVtk expression vector had a therapeutic effect on the occult peritoneal dissemination model mice.
Gasdermin-B promotes invasion and metastasis in breast cancer cells
Results confirmed the genetic association between GSDMB/ ORMDL3 (show ORMDL3 Antibodies) and childhood asthma and show significant differences in the DNA methylation (show HELLS Antibodies) levels of ORMDL3 (show ORMDL3 Antibodies) promoter of asthmatic children.
3 SNPs associated with the fraction of exhaled nitric oxide in childhood asthma are rs3751972 in LYRM9; rs944722 in NOS2 (show NANOS2 Antibodies); and rs8069176 near GSDMB; all at 17q12-q21.
rs11078928 is associated with the production of a novel GSDMB transcript lacking an internal segment
No association between GSDMB polymorphisms and rheumatoid arthritis was observed.
GSDMB SNP rs2305480 (Ser311Pro) was associated with asthma diagnosis (p = 8.9x10-4), bronchial hyperresponsiveness to methacholine (p = 8.2x10-4) and severity (p = 1.5x10-4) with supporting evidence from a second GSDMB SNP rs11078927 (intronic).
GSDMB/ORMDL3 (show ORMDL3 Antibodies) variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness.
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
, gasdermin-like protein