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Gastric Inhibitory Polypeptide Proteins (GIP)

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Additionally we are shipping GIP Kits (57) and GIP Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GIP 100718575 Q9D8T2
GIP 2695 P09681
GIP 25040 Q06145
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Top GIP Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$1,994.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$1,994.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Synthetic Human Ovalbumin   100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Human Cells Human Fc Tag   100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GIP Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , ,
, , ,
Rat (Rattus)

More Proteins for Gastric Inhibitory Polypeptide (GIP) Interaction Partners

Mouse (Murine) Gastric Inhibitory Polypeptide (GIP) interaction partners

  1. The loss of food-induced GIP response in Roux-limb of intestine likely contributes to the attenuated serum GIP response to feeding.

  2. GIP induces the expression of the proatherogenic cytokine osteopontin (OPN) in mouse arteries via local release of endothelin-1 and activation of CREB. GIPR mRNA is higher in symptomatic carotid endarterectomy patients.

  3. These studies support the hypothesis that a reduction in GIP signaling using a GIP-neutralizing mAb might provide a useful method for the treatment and prevention of obesity and related disorders.

  4. This study provides evidences that GIP acts directly on osteoblasts and is capable of improving collagen maturity and fibril diameter.

  5. There was decrease in GIP gene transcripts and protein in the gut (show GUSB Proteins) of HNF1a (show HNF1A Proteins)-null mice.

  6. The patterns of colocalisation of the K cell marker, glucagon-like insulinotropic peptide, and the L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated.

  7. These data indicate that GLP-1 (show GCG Proteins) but not GIP is a key mediator of beta cell mass expansion and related adaptations in pregnancy, triggered in part by generation of intra-islet GLP-1 (show GCG Proteins).

  8. NUCB2/nesfatin-1 (show NUCB2 Proteins) is co-localized with GLP-1 (show GCG Proteins) and GIP in small intestinal cells. Data support the hypothesis that nesfatin-1 (show NUCB2 Proteins) is present in enteroendocrine cells and that it stimulates incretin secretion.

  9. Circulating levels of GIP were significantly decreased in FABP5 (show FABP5 Proteins)-deficient mice.

  10. phosphatidylinositol 3-kinase gamma has a role in insulin (show INS Proteins) secretion induced by glucose-dependent insulinotropic polypeptide

Human Gastric Inhibitory Polypeptide (GIP) interaction partners

  1. Our results might indicate an altered DPP4 (show DPP4 Proteins)-incretin system and altered immunoregulation including a potentially dysfunctional GLP1 (show GCG Proteins)(9)(-)(36) signaling in T1DM.

  2. Fasting GIP concentrations are higher in individuals with a history of cardiovascular disease (myocardial infarction, stroke) when compared with control subjects.

  3. Data suggest that high levels of blood glucose or AGEs (advanced glycation end products), as seen in hyperglycemia, reduce secretion of insulin (show INS Proteins) by pancreatic beta cells via antagonism of GIP (gastric inhibitory polypeptide)/GIP receptor signaling.

  4. Data confirm that postprandial plasma levels of glucose-dependent insulinotropic polypeptide (GIP) and insulin (INS (show INS Proteins)) are responsive to glycemic index of foods consumed; glycemic index of breakfast cereals regulate plasma postprandial GIP and INS (show INS Proteins).

  5. irisin (show FNDC5 Proteins) and GIP might contribute to the development of polycystic ovary syndrome and may also represent novel polycystic ovary syndrome biomarkers

  6. Data suggest that postprandial blood levels of both GIP and insulin (show INS Proteins) can be regulated by diet; here, inclusion of nopal/Opuntia/cactus (show SLC25A20 Proteins) (a functional food in traditional Mexican medicine) in breakfast reduces postprandial levels of GIP and insulin (show INS Proteins).

  7. phosphatidylinositol 3-kinase gamma has a role in insulin (show INS Proteins) secretion induced by glucose-dependent insulinotropic polypeptide

  8. These novel results support the notion that the GIP-GIPR (show GIPR Proteins) axis plays a role in the etiology of central obesity in humans

  9. Data from studies in healthy Japanese men suggest that plasma GIP levels in postprandial period are dose dependently increased by fat content of meals of ordinary size, despite the amount of additional fat being relatively small.

  10. Dietary fructose elicits GLP-1 (show GCG Proteins) secretion without simultaneous release of glucagonotropic GIP.

Pig (Porcine) Gastric Inhibitory Polypeptide (GIP) interaction partners

  1. The patterns of colocalisation of the K cell marker, glucagon-like insulinotropic peptide, and the L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated.

  2. porcine GIP stimulated the proliferation of MC-26 (show Glycam1 Proteins) cells, a mouse CRC cell line, in a concentration-dependent manner.

GIP Protein Profile

Protein Summary

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Gene names and symbols associated with GIP

  • gasdermin D (Gsdmd)
  • apolipoprotein A-Ib (apoa1b)
  • gastric inhibitory polypeptide (GIP)
  • gastric inhibitory polypeptide (gip)
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1)
  • gastric inhibitory polypeptide (Gip)
  • gastric inhibitory polypeptide-like (LOC100350350)
  • gastric inhibitory polypeptide-like (LOC100621117)
  • gastric inhibitory polypeptide-like (LOC100856162)
  • 1810036L03Rik protein
  • AW558049 protein
  • DF5L protein
  • Dfna5l protein
  • GIP protein
  • Gludins protein
  • Gsdmdc1 protein
  • M2-4 protein
  • Nif3 protein
  • NLIIF protein
  • RATGLUDINS protein
  • SCP1 protein
  • wu:fb66d03 protein
  • wu:fd19c08 protein
  • xgip protein
  • xx:sd49 protein

Protein level used designations for GIP

gasdermin domain containing 1 , gasdermin domain-containing protein 1 , gasdermin-D , gastric inhibitory polypeptide , glucose-dependent insulinotropic polypeptide , NLI-interacting factor 3 , carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , golli-interacting protein , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , small CTD phosphatase 1 , incretin hormone , Glucose-dependent insulinotropic peptide

GENE ID SPECIES
100718575 Mus musculus
100101640 Danio rerio
749143 Pan troglodytes
100036740 Xenopus (Silurana) tropicalis
698335 Macaca mulatta
609020 Canis lupus familiaris
100037247 Xenopus laevis
227292 Mus musculus
2695 Homo sapiens
100533199 Sus scrofa
25040 Rattus norvegicus
14607 Mus musculus
511073 Bos taurus
419989 Gallus gallus
101113509 Ovis aries
100350350 Oryctolagus cuniculus
100621117 Sus scrofa
100856162 Canis lupus familiaris
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