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GRP encodes a member of the bombesin-like family of gastrin-releasing peptides. Additionally we are shipping Gastrin-Releasing Peptide Kits (34) and Gastrin-Releasing Peptide Proteins (5) and many more products for this protein.
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Chicken Polyclonal Gastrin-Releasing Peptide Primary Antibody for IEM, ICC - ABIN617886
Westlund, Lu, Werrbach-Perez, Hulsebosch, Morgan, Pizzo, Eisenberg, Perez-Polo: Effects of nerve growth factor and acetyl-L-carnitine arginyl amide on the human neuronal line HCN-1A. in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1993
Show all 44 references for ABIN617886
Fos and phosphorylation of extracellular signal-regulated kinases (ERK (show EPHB2 Antibodies)) were used to look for evidence that interneurons expressing GRP (show UCMA Antibodies) were activated following intradermal injection of chloroquine.
GRP (show UCMA Antibodies) is expressed by a distinct population of excitatory interneurons in laminae I-II that are likely to be involved in the itch pathway
BNP (show BNC2 Antibodies)-NPRA (show NPR1 Antibodies) signaling is involved in both itch and pain and does not function upstream of the GRP (show UCMA Antibodies)-GRPR (show GRPR Antibodies) dedicated neuronal pathway.
The majority of dorsal spinal cord Grp is synthesized locally in dorsal spinal cord neurons while Nmb is highly expressed in pain- and itch-sensing dorsal root ganglion neurons.
nonamidated peptides derived from the C terminus of pro-GRP (show UCMA Antibodies) are expressed in significant quantities in colorectal cancer cell lines
GRP (show UCMA Antibodies) delays the phase of the clock during the early night by prolonging day-like membrane properties of SCN (show SRI Antibodies) cells
The GRP (show UCMA Antibodies) receptor system does not mediate kappa opioid receptor (show OPRK1 Antibodies) antagonist (GNTI (show MGAT1 Antibodies))-induced scratching. The kappa opioid system is involved, at least in part, in the scratch suppressing activity of the kappa opioid receptor (show OPRK1 Antibodies) agonist nalfurafine.
These studies demonstrate that (64)Cu-SarAr-SA-Aoc-bombesin(7-14) and (64)Cu-SarAr-SA-Aoc-GSG-bombesin(7-14) bound with high affinity to GRPR (show GRPR Antibodies)-expressing cells.
A general possible effect of GRP (show UCMA Antibodies) on cortical inhibitory transmission, was shown.
GRP/GRP (show UCMA Antibodies)-R (show GRPR Antibodies) play a transient and non-critical role in intestinal development
CEA (show CEACAM5 Antibodies), NSE (show ENO2 Antibodies), CA125 (show MUC16 Antibodies) and pro-GRP (show LSM4 Antibodies) could serve as biomarkers for SCLC, and CEA (show CEACAM5 Antibodies) and CYFRA21-1 could serve as biomarkers for NSCLC. Pro-GRP (show LSM4 Antibodies), CA125 (show MUC16 Antibodies) and CEA (show CEACAM5 Antibodies) were related to the clinical stages of lung cancer
Data show that serum neuron-specific enolase (show ENO2 Antibodies), cytokeratin 19 (show KRT19 Antibodies) fragment 21-1, pro-gastrin-releasing peptide, squamous cell carcinoma antigen, tissue inhibitor of metalloproteinase-1, and human epididymis protein 4 are not associated with brain metastases.
No association of 16 GRP (show LSM4 Antibodies) and 7 GRPR (show GRPR Antibodies) variants were found with agoraphobia with/without panic disorder.
the role of autophagy in the degradation of gastrin-releasing peptide and subsequent inhibition of angiogenesis
The Gastrin-releasing peptide(GRP)triggers the growth of HepG2 cells through blocking the ER stress-mediated pathway.
GRP (show LSM4 Antibodies) silencing decreases anchorage-independent growth, inhibits cell migration and neuroblastoma (show ARHGEF16 Antibodies) cell-mediated angiogenesis.
GRP (show LSM4 Antibodies)-expressing C and A delta fibers that coexpress SP or CGRP (show S100A12 Antibodies) makes these neurons pruriceptors.
The levels of GRP (show LSM4 Antibodies) were upregulated in cells treated with HGF (show HGF Antibodies) in a dose-dependent manner. HGF (show HGF Antibodies)-induced expression of Ets-1 (show ETS1 Antibodies) and IL-8 (show IL8 Antibodies) was increased more by GRP (show LSM4 Antibodies) treatment.
GRP (show LSM4 Antibodies) serum level is higher in patients with pruritus in patients with atopic dermatitis.
Tonic stretch of human myometrium increases contractility and stimulates the expression of a known smooth muscle stimulatory agonist, GRP (show LSM4 Antibodies). GRP (show LSM4 Antibodies) receptor antagonists attenuate the effect of stretch.
GRP may be important both in the endometrial remodeling during the estrous cycle and in the implantation and development of blastocysts
The present results revealed the localization of GRP in the uterine gland cells at light- and electron-microscopic levels and suggested the release of GRP from the cell into the lumen of the gland by exocrine manner.
GRP may be important both in the development of the fetal cervix and secretory activity of the epithelial cells of the cervix.
This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
, neuromedin C
, pre-progastrin releasing peptide
, proventricular peptide
, submandibular gland secretory Glx-rich protein
, uncharacterized protein LOC232426
, Gla-rich protein
, unique cartilage matrix-associated protein