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Gastrulation Brain Homeo Box 2 Proteins (GBX2)

May act as a transcription factor for cell pluripotency and differentiation in the embryo. Additionally we are shipping GBX2 Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GBX2 2637 P52951
GBX2 14472 P48031
Rat GBX2 GBX2 114500  
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Top GBX2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,920.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,920.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

GBX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Gastrulation Brain Homeo Box 2 (GBX2) Interaction Partners

Zebrafish Gastrulation Brain Homeo Box 2 (GBX2) interaction partners

  1. Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner.

  2. in the zebrafish gbx1 and gbx2 are required redundantly for morphogenesis of the cerebellar primordium and subsequent cerebellar differentiation, but that this requirement is alleviated by knocking down Otx

  3. gbx2/Gbx2 has an evolutionarily conserved role in anterior hindbrain development.

  4. Here we report the isolation, mapping, chromosomal synteny and spatiotemporal expression of gbx1 and gbx2 in zebrafish. We focus in particular on the expression of these genes during development of the midbrain-hindbrain territory.

  5. Ectopic expression of gbx2 by mRNA injection caused cyclopia or truncation of the fore- and midbrain and severely affected isthmic and cerebellar structures.

  6. gbx2 expression during the somitogenesis stage in zebrafish is regulated by a complex mechanism involving Pax2 (show PAX2 Proteins) as well as activators and suppressors in the regions flanking the gene.

Human Gastrulation Brain Homeo Box 2 (GBX2) interaction partners

  1. Data established a seven-gene (AR, ESR2 (show ESR2 Proteins), GATA3 (show GATA3 Proteins), GBX2, KRT16 (show KRT16 Proteins), MMP28 (show MMP28 Proteins) and WNT11 (show WNT11 Proteins)) prognostic signature to define a subset of triple-negative breast cancer (TNBC).

  2. Gbx2 and Otx2 (show OTX2 Proteins) interact with the WD40 domain (show DCAF12L2 Proteins) of Groucho/Tle corepressors

Mouse (Murine) Gastrulation Brain Homeo Box 2 (GBX2) interaction partners

  1. Deregulated FGF8 (show FGF8 Proteins) and Otx2 (show OTX2 Proteins)/Gbx2 gene expression underlies cerebellar vermis hypoplasia in mouse model of CHARGE syndrome.

  2. Gbx2 is essential for the acquisition of the thalamic neuronal identity by repressing habenular identity through a feedback signaling from postmitotic neurons to progenitors

  3. Results reveal a novel function of Gbx2 in mESC reprogramming and LIF (show LIF Proteins)/Stat3 (show STAT3 Proteins)-mediated self-renewal.

  4. Results indicate that the dynamic expression of Gbx2 may act as an important determinant in coupling with other developmental programs to generate distinct thalamic nuclei.

  5. Identified are several GBX2 candidate target genes including ROBO1 (show ROBO1 Proteins), PLXNA4 (show PLXNA4 Proteins), SLIT3 (show SLIT3 Proteins), NRP1 (show NRP1 Proteins), PCDH15 (show PCDH15 Proteins), USH2A, NOTCH2 (show NOTCH2 Proteins), and EEF1A1 (show EEF1A1 Proteins) that are likely to contribute many of the developmental defects observed in Gbx2 mutant organisms.

  6. Gbx2 regulates thalamocortical axon guidance by modifying the LIM (show PDLIM5 Proteins) and Robo codes.

  7. the Gbx2 homeodomain recognizes the target TAATTA in the FM enhancer, and Gbx2 associates with the FM enhancer in the hindbrain

  8. long-term lineage analysis reveals that the presence and timing of Gbx2 expression in interneuron progenitors results in the differential contribution to subtypes of terminally differentiated interneurons in the adult spinal cord

  9. gbx2/Gbx2 has an evolutionarily conserved role in anterior hindbrain development.

  10. findings reveal the distinct function of Gbx2 and Fgf8 (show FGF8 Proteins) in a stepwise process in the development of the compartment boundary at the midbrain-hindbrain border

GBX2 Protein Profile

Protein Summary

May act as a transcription factor for cell pluripotency and differentiation in the embryo.

Gene names and symbols associated with GBX2

  • gastrulation brain homeo box 2 (gbx2)
  • gastrulation brain homeobox 2 (GBX2)
  • gastrulation brain homeobox 2 (Gbx2)
  • gastrulation brain homeobox 2, gene 2 (gbx2.2)
  • D130058E05Rik protein
  • fd07f12 protein
  • Gbx-2 protein
  • gbx2 protein
  • MMoxA protein
  • Stra7 protein
  • wu:fd07f12 protein

Protein level used designations for GBX2

homeobox protein GBX-2 , gastrulation brain homeobox 2 , gastrulation brain homeo box 2 , gastrulation and brain-specific homeobox protein 2 , stimulated by retinoic acid gene 7 protein , XGBX-2 , homeobox protein Xgbx-2

GENE ID SPECIES
245948 Danio rerio
470689 Pan troglodytes
2637 Homo sapiens
486174 Canis lupus familiaris
507344 Bos taurus
14472 Mus musculus
114500 Rattus norvegicus
100514608 Sus scrofa
395950 Gallus gallus
397824 Xenopus laevis
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