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Regulator of DNA replication. Additionally we are shipping Geminin Coiled-Coil Domain Containing Proteins (3) and and many more products for this protein.
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Human Polyclonal GMNC Primary Antibody for EIA, WB - ABIN783498
Piergiovanni, Costanzo: GEMC1 is a novel TopBP1-interacting protein involved in chromosomal DNA replication. in Cell cycle (Georgetown, Tex.) 2010
The crystal structure of a GemC1 coiled-coil domain variant engineered for better solubility was determined to 2.2 A resolution.
GemC1 directly transactivates the promoters of MCIDAS and FOXJ1 (show FOXJ1 Antibodies).
Results suggest that Mcidas and GemC1 are key players in the generation of multiciliated ependymal cells of the adult neurogenic niche.
GEMC1 promotes initiation of chromosomal DNA replication in multicellular organisms by mediating TopBP1 (show TOPBP1 Antibodies)- and Cdk2 (show CDK2 Antibodies)-dependent recruitment of Cdc45 (show CDC45 Antibodies) onto replication origins.
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2- dependent recruitment of CDC45L onto replication origins (By similarity).
geminin coiled-coil domain-containing protein 1
, GEMinin-containing coiled-coil domain 1
, replication factor GEMC1