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GTF2B encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. Additionally we are shipping General Transcription Factor IIB Proteins (23) and General Transcription Factor IIB Kits (20) and many more products for this protein.
Showing 10 out of 123 products:
Dog (Canine) Monoclonal GTF2B Primary Antibody for IF, IP - ABIN967987
Bagby, Kim, Maldonado, Tong, Reinberg, Ikura: Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein. in Cell 1995
Show all 4 references for 967987
Cow (Bovine) Polyclonal GTF2B Primary Antibody for WB - ABIN2787507
Elsby, ODonnell, Green, Sharrocks, Roberts: Assembly of transcription factor IIB at a promoter in vivo requires contact with RNA polymerase II. in EMBO reports 2006
Dog (Canine) Polyclonal GTF2B Primary Antibody for IHC, WB - ABIN2792692
Tubon, Tansey, Herr: A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment. in Molecular and cellular biology 2004
binding of specific DNA sequences changes the protein structure and dynamics, and TFIIB may exist in two conformational states
The role of zinc at Cys3His1 binding site in the absence of TFIIB protein folding
these results establish a new paradigm for TFIIB functionality in human gene expression, which when downregulated has potent anti-viral effects.
Association of the winged helix motif of the TFIIEalpha subunit of TFIIE with either the TFIIEbeta subunit or TFIIB distinguishes its functions in transcription.
TFIIB was involved in the proliferation and growth of HCC (show FAM126A Antibodies) cells.
a mode of phospho-TFIIB-independent transcriptional regulation that prioritizes the transcription of p53 (show TP53 Antibodies)-target genes during cellular stress.
Data show that TFIIF (show GTF2F1 Antibodies) has an important role in stabilizing TFIIB within the PIC and after transcription initiates.
a six-amino acid human TFIIB tip region is needed for appropriate levels of serine 5 C-terminal domain phosphorylation and mRNA capping and for retention of the required elongation factor (show TSFM Antibodies) TFIIF (show GTF2F1 Antibodies).
phosphorylation of TFIIB at serine 65 is a critical event in transcription that links the gene promoter and terminator and triggers initiation by RNA pol II
interaction with vitamin D receptor (show VDR Antibodies) helix H10 (show H1F0 Antibodies) residues
by acutely targeting TFIIB, we were able to inhibit selectively the former set of genes and ameliorate pressure overload hypertrophy.
TFIIB co-localizes and interacts with alpha-tubulin (show TUBA4A Antibodies) during oocyte meiosis in the mouse and depletion of TFIIB causes arrest of subsequent embryo development.
Study suggest that components of the transcription machinery decreased in accordance with cell differentiation and that TFIIB is specifically and rapidly degraded by the ubiquitin-proteasome pathway.
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
, transcription factor IIB
, transcription initiation factor iib
, transcription initiation factor IIB
, transcription initiation factor iiB
, Transcription initiation factor IIB
, hypothetical protein
, general transcription factor IIB
, general transcription factor TFIIB
, RNA polymerase II transcription factor IIB
, RNA polymerase II alpha initiation factor