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General Transcription Factor IIH, Polypeptide 2, 44kDa Proteins (GTF2H2)

GTF2H2 is part of a 500 kb inverted duplication on chromosome 5q13. Additionally we are shipping GTF2H2 Antibodies (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GTF2H2 23894 Q9JIB4
GTF2H2 294693 A0JN27
GTF2H2 2966 Q13888
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Top GTF2H2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Caenorhabditis elegans His tag   1 mg Log in to see 56 to 66 Days
$3,032.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,094.67
Details

GTF2H2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,
,

More Proteins for General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) Interaction Partners

Mouse (Murine) General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) interaction partners

  1. p44 (show GTF2H4 Proteins) of TFIIH (show GTF2H4 Proteins) has a role in binding to the nonstructural protein of Rift Valley fever virus to form nuclear filamentous structures

Human General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2) interaction partners

  1. Advanced oxidation protein products down-regulate the expression of calcium transport channels through p44/42 MAPK (show MAPK1 Proteins) signaling mechanisms in the small intestinal epithelium.

  2. Together, these results suggest that p44/WDR77 expression causes the non-sensitivity of proliferating cells to TGFbeta (show TGFB1 Proteins) signaling, thereby contributing to cellular proliferation during lung tumorigenesis.

  3. No correlation was found for p44 and occludin (show OCLN Proteins) gene copy number and spinal muscular atrophy

  4. miR (show MLXIP Proteins)-27a was identified as a key regulator of p44 mRNA. Moreover, miR (show MLXIP Proteins)-27a was shown to destabilize the p44 subunit of the TFIIH (show GTF2H1 Proteins) complex during the G2-M phase, thereby modulating the transcriptional shutdown observed during this transition.

  5. p52 (show FKBP4 Proteins) Mediates XPB (show GTF2H5 Proteins) function within the transcription/repair factor

  6. p44 of TFIIH (show GTF2H1 Proteins) has a role in binding to the nonstructural protein of Rift Valley fever virus to form nuclear filamentous structures

  7. solution structure of p44-(321-395) shows topology differs from other reported RING domains by a circular permutation of the extended secondary structure elements; mutagenesis suggests tight binding to p34 (show CCNH Proteins) is mediated by hydrophobic interactions

GTF2H2 Protein Profile

Protein Summary

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs\; however, no sequence data is currently available for the centromeric copy of the gene.

Gene names and symbols associated with GTF2H2

  • general transcription factor II H, polypeptide 2 (Gtf2h2)
  • general transcription factor IIH, polypeptide 2 (Gtf2h2)
  • general transcription factor IIH, polypeptide 2, 44kDa (GTF2H2)
  • 44kDa protein
  • BTF2 protein
  • BTF2 p44 protein
  • BTF2-p44 protein
  • BTF2P44 protein
  • p44 protein
  • T-BTF2P44 protein
  • TFIIH protein

Protein level used designations for GTF2H2

TFIIH basal transcription factor complex p44 subunit , basal transcription factor 2, p44 subunit , basic transcription factor 2 44 kDa subunit , general transcription factor II H, polypeptide 2 (44 kDa subunit) , general transcription factor IIH subunit 2 , general transcription factor IIH, polypeptide 2 (44 kDa subunit) , BTF2-p44 , BTF2 p44 , general transcription factor IIH polypeptide 2 , general transcription factor IIH, polypeptide 2, 44kD subunit

GENE ID SPECIES
23894 Mus musculus
294693 Rattus norvegicus
2966 Homo sapiens
511829 Bos taurus
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