You are viewing an incomplete version of our website. Please click to reload the website as full version.

Germ Cell Associated 2 (Haspin) Proteins (GSG2)

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. Additionally we are shipping Germ Cell Associated 2 (Haspin) Antibodies (48) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSG2 83903 Q8TF76
Rat GSG2 GSG2 687827  
GSG2 14841 Q9Z0R0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Germ Cell Associated 2 (Haspin) Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

GSG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Germ Cell Associated 2 (Haspin) (GSG2) Interaction Partners

Fruit Fly (Drosophila melanogaster) Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

Human Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

  1. Haspin kinase plays a key role in maintaining the slowly exchanging centromere Borealin (show CDCA8 Proteins) pool.

  2. Haspin activity affects the phosphorylation state of proteins involved in gene expression regulation and splicing.

  3. Haspin inhibitors reveal centromeric roles of Aurora B (show AURKB Proteins) in chromosome movement and spindle checkpoint signaling

  4. Aurora B (show AURKB Proteins) phosphorylates Haspin to promote generation of H3T3ph and that Aurora B kinase (show AURKB Proteins) activity is required for normal chromosomal localization of the CPC, indicating an intimate linkage between Aurora B (show AURKB Proteins) and Haspin functions in mitosis

  5. findings show phosphorylation of histone H3-threonine 3 mediated by Haspin cooperates with Bub1-mediated histone 2A-serine 121 phosphorylation in targeting the chromosomal passenger complex to the inner centromere in fission yeast and human cells

  6. phosphorylation of H3T3 by Haspin is necessary for chromosomal passenger complex(CPC) accumulation at centromeres; Survivin (show BIRC5 Proteins) binds to H3T3ph; H3T3ph generated by Haspin positions CPC at centromeres to regulate selected targets of Aurora B (show AURKB Proteins) during mitosis

  7. Haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesion.

  8. Haspin is a relatively newly discovered kinase that phosphorylates histone H3 (show HIST3H3 Proteins) during mitosis and appears to play a role in regulating chromosome behavior during cell division. [REVIEW]

  9. This work reveals a new kinase involved in composing the histone code and adds haspin to the select group of kinases that integrate regulation of chromosome and spindle function during mitosis and meiosis

  10. Haspin is required to maintain centromeric cohesion during mitosis.

Mouse (Murine) Germ Cell Associated 2 (Haspin) (GSG2) interaction partners

  1. Data implicate haspin as a regulator of the chromosomal passenger complex and chromosome segregation during meiosis I.

  2. the tissue-dependent and differentially methylated region functions as a modulator in a DNA methylation (show HELLS Proteins)-dependent manner; Gsg2 is under epigenetic control

  3. the 193-bp DNA sequence in Haspin promotor is sufficient for the specific, bidirectional, and synchronous expression in germ cells in the testis.

Germ Cell Associated 2 (Haspin) (GSG2) Protein Profile

Protein Summary

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle (By similarity).

Gene names and symbols associated with GSG2

  • serine/threonine-protein kinase haspin-like protein (Haspin)
  • germ cell associated 2 (haspin) (GSG2)
  • CG40080 gene product from transcript CG40080-RA (Haspin)
  • putative serine/threonine-protein kinase haspin homolog (Haspin)
  • germ cell associated 2 (haspin) (Gsg2)
  • germ cell-specific gene 2 (Gsg2)
  • BcDNA:LD07633 protein
  • CG40080 protein
  • Dmel\\CG40080 protein
  • Haspin protein
  • NV16901 protein

Protein level used designations for GSG2

serine/threonine-protein kinase haspin-like protein , germ cell associated 2 (haspin) , haspin , CG40080-PA , Haspin-PA , putative serine/threonine-protein kinase haspin homolog , H-haspin , germ cell-specific gene 2 protein , haploid germ cell-specific nuclear protein kinase , serine/threonine-protein kinase haspin

GENE ID SPECIES
552287 Apis mellifera
748101 Pan troglodytes
3355064 Drosophila melanogaster
100122327 Nasonia vitripennis
83903 Homo sapiens
767819 Bos taurus
687827 Rattus norvegicus
14841 Mus musculus
Selected quality suppliers for Germ Cell Associated 2 (Haspin) Proteins (GSG2)
Did you look for something else?