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Germinal Center Expressed Transcript 2 Proteins (GCET2)

GCET2 encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. Additionally we are shipping Germinal Center Expressed Transcript 2 Antibodies (29) and Germinal Center Expressed Transcript 2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GCET2 14525 Q6RFH4
GCET2 257144 Q8N6F7
Rat GCET2 GCET2 685692  
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Top Germinal Center Expressed Transcript 2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GCET2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced Germinal Center Expressed Transcript 2 Proteins

  1. Human GCET2 Protein expressed in Escherichia coli (E. coli) - ABIN1098460 : Temmins, Zhao, Lossos, Natkunam: HGAL protein expression persists in disorders of germinal center dissolution: potential role of HGAL in the germinal center microenvironment. in Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2011 (PubMed)
    Show all 2 references for ABIN1098460

More Proteins for Germinal Center Expressed Transcript 2 (GCET2) Interaction Partners

Mouse (Murine) Germinal Center Expressed Transcript 2 (GCET2) interaction partners

  1. Assays identified a non-consensus binding site for Sp factors near sites of transcriptional initiation. The site binds Spl and Sp3 in nuclear extracts.

Human Germinal Center Expressed Transcript 2 (GCET2) interaction partners

  1. Diagnostic Utility of the Germinal Center-associated Markers GCET1 (show SERPINA9 Proteins), HGAL, and LMO2 (show LMO2 Proteins) in Hematolymphoid Neoplasms.

  2. These findings further elucidate the growing and complex role of HGAL in B-cell biology and suggest that membrane-bound and cytoplasmic HGAL protein differently regulates distinct biological processes.

  3. HGAL and LMO2 (show LMO2 Proteins) may be useful adjuncts in the identification of follicular lymphoma of the nongastric gastrointestinal tract.

  4. the germinal centre protein human germinal centre-associated lymphoma regulates B-cell receptor signalling in B-lymphocytes which, without appropriate control, may lead to B (show TDO2 Proteins)-cell lymphoproliferation (show FAS Proteins).

  5. HGAL/GCET2 protein expression may function as a marker for germinal center B-cell type diffuse large B-cell lymphoma.

  6. Immunostaining for HGAL was more frequently positive than that for BCL6 (show BCL6 Proteins) and CD10 (show MME Proteins) in follicular lymphomas

  7. Data suggest that both HGAL and LMO2 (show LMO2 Proteins) are directly regulated by the transcription repressor PRDM1 (show PRDM1 Proteins)--overexpression of PRDM1 (show PRDM1 Proteins) down-regulates HGAL and LMO2 (show LMO2 Proteins); PRDM1 (show PRDM1 Proteins) directly binds to promoters of both HGAL and LMO2 (show LMO2 Proteins) and represses genetic transcription.

  8. show that HGAL increases the binding of myosin to F-actin and inhibits the ability of myosin to translocate actin by reducing the maximal velocity of myosin head/actin movement

  9. HGAL is sensitive and specific marker for detecting follicular lymphoma in nodal and extranodal sites

  10. molecular mechanism underlying the inhibitory effects of germinal center-specific HGAL protein on the motility of GC-derived lymphoma cells

Germinal Center Expressed Transcript 2 (GCET2) Protein Profile

Protein Summary

This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with GCET2

  • germinal center associated, signaling and motility (Gcsam)
  • germinal center-associated, signaling and motility (GCSAM)
  • germinal center-associated, signaling and motility (Gcsam)
  • GCAT2 protein
  • Gcet protein
  • GCET2 protein
  • HGAL protein
  • M17 protein
  • M17-L protein

Protein level used designations for GCET2

germinal center B-cell-expressed transcript 2 protein , germinal center expressed transcript 2 , germinal center-associated signaling and motility protein , germinal center-associated lymphoma protein , human germinal center-associated lymphoma

GENE ID SPECIES
14525 Mus musculus
257144 Homo sapiens
685692 Rattus norvegicus
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