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anti-Ghrelin/obestatin Prepropeptide (GHRL) Antibodies

GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Additionally we are shipping Ghrelin/obestatin Prepropeptide Kits (131) and Ghrelin/obestatin Prepropeptide Proteins (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GHRL 58991 Q9EQX0
GHRL 51738 Q9UBU3
GHRL 59301 Q9QYH7
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Top anti-Ghrelin/obestatin Prepropeptide Antibodies at

Showing 10 out of 265 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, IF, IHC (p) 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated WB GHRL monoclonal antibody (M01), clone 2F4. Western Blot analysis of GH... 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain tissue labeled with Ant... 100 μL Log in to see 3 to 7 Days
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to GHRL on formalin-fixed para... GHRL monoclonal antibody (M01), clone 2F4. Western Blot analysis of GH... 100 μg Log in to see 9 Days
Human Goat Un-conjugated IHC (p), ELISA Human Placenta (formalin-fixed, paraffin-embedded) stained with GHRL a... Human Colon (formalin-fixed, paraffin-embedded) stained with GHRL anti... 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated WB   100 μg Log in to see 2 to 3 Days
Cat Rabbit Un-conjugated WB   100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
Human Goat Un-conjugated ICC, IHC, ELISA 0.1 mg Log in to see 2 to 3 Days

GHRL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-Ghrelin/obestatin Prepropeptide Antibodies

  1. Human Monoclonal GHRL Primary Antibody for WB - ABIN395595 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395595

  2. Human Polyclonal GHRL Primary Antibody for IHC, ELISA - ABIN185450 : Ghigo, Broglio, Arvat, Maccario, Papotti, Muccioli: Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor. in Clinical endocrinology 2005 (PubMed)
    Show all 2 references for ABIN185450

  3. Human Polyclonal GHRL Primary Antibody for EIA, IF - ABIN452691 : Stoyanova, Wiertz, Rutten: Time-dependent changes in ghrelin-immunoreactivity in dissociated neuronal cultures of the newborn rat neocortex. in Regulatory peptides 2009 (PubMed)

  4. Human Monoclonal GHRL Primary Antibody for IHC (p), ELISA - ABIN565666 : Goitein, Lederfein, Tzioni, Berkenstadt, Venturero, Rubin: Mapping of ghrelin gene expression and cell distribution in the stomach of morbidly obese patients--a possible guide for efficient sleeve gastrectomy construction. in Obesity surgery 2012 (PubMed)

  5. Human Polyclonal GHRL Primary Antibody for IF (p), IHC (p) - ABIN668991 : Lemarié, Beauchamp, Dayot, Duby, Legrand, Rioux: Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. in PLoS ONE 2015 (PubMed)

More Antibodies against Ghrelin/obestatin Prepropeptide Interaction Partners

Mouse (Murine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Data show that chronic caloric restriction (CR) alters hypothalamic agouti-related protein (Agrp (show AGRP Antibodies)) and neuropeptide Y (Npy (show NPY Antibodies)) gene expression similarly in Ghrelin+/+, Ghrelin-/-, ghrelin receptor Ghsr (show GHSR Antibodies)+/+, and Ghsr (show GHSR Antibodies)-/- mice.

  2. The expression of ghrelin and GH secretagogue receptor 1a [GHSR1a] in cerebral arteries and the effects of ghrelin analogs on cerebrovascular function are reproted.[GHSR1a]

  3. Pax6 (show PAX6 Antibodies) inactivation in the adult pancreas reveals ghrelin as endocrine cell maturation marker.

  4. Thus, GHSR1a differentially inhibits CaV2 (show CAV2 Antibodies) channels by Gi/o or Gq protein pathways depending on its mode of activation.

  5. results demonstrate that ghrelin, which signals acute hunger, renders the olfactory system more responsive to odors

  6. investigated whether ghrelin may cause alteration in neurite outgrowth and electrophysiological properties of tyrosine hydroxylase (show TH Antibodies) neurons from the ventrolateral arcuate nucleus

  7. Ghrelin is an inducer of myoprotective autophagy in myocardial and skeletal muscle ischemia.

  8. The expressions of both ghrelin and its receptor were observed in NPCs using RT-PCR, Interestingly, the exposure of fetal NPCs to ghrelin suppressed their proliferation, and caused them to differentiate into neurons

  9. Co-localization of TRPA1 (show TRPA1 Antibodies) and ghrelin in enteroendocrine cells of the duodenum is observed both in vivo and in the MGN3-1 cell line, a ghrelin secreting cell model, where incubation with CIN (show PDXP Antibodies) up-regulates expression of TRPA1 (show TRPA1 Antibodies) and Insulin receptor (show INSR Antibodies) genes.

  10. Overproduction of ghrelin via an AAV viral delivery system in the hypothalamus leads to an increase in food intake associated with increases in body weight. This effect disappears after 3 weeks.

Rabbit Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Study suggests that ghrelin promotes the growth and osteogenic differentiation of rBMSC primarily through the ERK1/2 (show MAPK1/3 Antibodies) pathway.

Rainbow Trout (Oncorhynchus mykiss) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Data show that ghrelin was identified in cultured differentiated adipocytes, but did not influence either preadipocyte proliferation or differentiation, indicating that it may have other adipose-related roles.

  2. data provides evidence for the first time in fish of a possible modulatory role of ghrelin on the metabolic regulation by fatty acid of food intake occurring in the hypothalamus

Human Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. circulating ghrelin, but not PYY(3-36), levels are increased in neonates with infection, possibly reflecting and/or participating in the inflammatory process

  2. Ghrelin modulates GLUT1 (show SLC2A1 Antibodies) expression and thus indirectly enhances tumor cell proliferation. These findings are of major relevance, because glucose uptake is assumed to be a promising target for cancer treatment.

  3. GH, IGF-1 (show IGF1 Antibodies) and ISI-Matsuda index were lower in the high fatty liver index group in obese subjects with fatty liver and sarcopenia.

  4. Among the gastroesophageal reflux disease patients, ghrelin levels were inversely associated with the frequency and severity of acid regurgitation

  5. the GHRL rs26311 polymorphism is associated with an increased risk to hepatitis B virus-related liver cirrhosis, especially in men.

  6. Ghrelin gene variants -604GA, -501AC and M72L are associated with certain components of metabolic syndrome

  7. Rs4684677 T/A polymorphisms in preproghrelin gene could contribute to development of AITDs in children and T allele is the main risk factor.

  8. In1-ghrelin, a splice variant of ghrelin gene, is associated with the evolution and aggressiveness of human pancreatic/gastrointestinal neuroendocrine tumors.

  9. GHRL secretion from gastric endocrine cells is influenced by factors including nutrients, hormones, and neural control; these factors influence each other directly/indirectly; circulating GHRL level is determined by sum of activities. [REVIEW]

  10. Higher levels of ghrelin were associated with an increased risk of Barrett's esophagus among the general population.

Cow (Bovine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Single nucleotide polymorphisms identified in the promoter region of the ghrelin gene could cause changes in the putative transcription factor (show TCF19 Antibodies) binding sites.

  2. The effects of dietary energy on the metabolism of ghrelin, leptin (show LEP Antibodies) and growth hormone secretagogue receptor (show GHSR Antibodies) in blood and tissues of steers are reported.

  3. ghrelin declined after glucose infusion and before the insulin (show INS Antibodies) peak; post-nadir surge in ghrelin may be regulated by the decline in circulating concentrations of glucose and nonesterified fatty acids

Goat Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. present findings suggest that ghrelin may play an important role in regulation of mammary function in lactating dairy goats via GHSR (show GHSR Antibodies)-1a

Pig (Porcine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Studied an alternative vascular approach to the modulation of gastric ghrelin levels..

  2. Obestatin enhances proliferation and differentiation of preadipocytes promoting PPARgamma (show PPARG Antibodies) and C/EBPa (show CEBPA Antibodies) expression, and inhibiting preadipocyte apoptosis by decreasing expression of Caspase-3 (show CASP3 Antibodies), Caspase-7 (show CASP7 Antibodies) and Caspase-9 (show CASP9 Antibodies).

  3. The expression of ghrelin in the digestive tract of low birth weight and normal weight piglets is reported.

  4. Data suggest that a dietary factor (here, high levels of dietary copper) is able to up-regulate expression of ghrelin in the fundic gland of growing pigs; the diets tested in this study also increase feed intake and promote weight gain.

  5. Ghrelin immunolocalization in the gastrointestinal tract of pigs at different ages were studied and it was concluded that gastric ghrelin expression is not related merely to age but could also potentially be influenced by food intake.

  6. BsrI polymorphism at the ghrelin gene locus is potentially associated with carcass and meat quality traits.

  7. Plasma concentrations of ghrelin were greater before feeding and decreased after feeding in pigs fed once per day; there was no consistent pattern to ghrelin secretion in the ad libitum fed group.

  8. glucose output by primary porcine hepatocytes in suspension culture, after incubation with acylated ghrelin (AG), unacylated ghrelin (UAG), and hexarelin (HEX).

  9. Immunization against ghrelin was associated with increased antibody titers, decreased voluntary food consumption, and decreased body weight gain by pigs.

  10. ghrelin mRNA expression is up-regulated 10 days after weaning in the gastric fundus of piglets, coinciding with the increase of H(+)-K(+)-ATPase (show ATP4b Antibodies) mRNA expression and activity

Ghrelin/obestatin Prepropeptide (GHRL) Antigen Profile

Protein Summary

This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake\; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression.

Gene names and symbols associated with GHRL

  • ghrelin (Ghrl) antibody
  • ghrelin-like (LOC100349547) antibody
  • ghrelin/obestatin preprohormone (ghrl) antibody
  • ghrelin/obestatin prepropeptide (GHRL) antibody
  • ghrelin/obestatin prepropeptide (Ghrl) antibody
  • 2210006E23Rik antibody
  • Gh1-1 antibody
  • GHR antibody
  • GRHL antibody
  • m46 antibody
  • MTLRP antibody
  • MTLRP-AP antibody
  • MTLRPAP antibody

Protein level used designations for GHRL

appetite-regulating hormone , growth hormone secretagogue , growth hormone-releasing peptide , motilin-related peptide , preproghrelin , proghrelin , ghrelin , ghrelin, growth hormone secretagogue receptor ligand , ghrelin/obestatin preprohormone , prepro-appetite regulatory hormone , Appetite-regulating hormone , Growth hormone secretagogue , Growth hormone-releasing peptide , prepro-ghrelin , GH releasing peptide , motilin related peptide , growth hormone receptor

58991 Mus musculus
100349547 Oryctolagus cuniculus
100136596 Oncorhynchus mykiss
51738 Homo sapiens
59301 Rattus norvegicus
281192 Bos taurus
100861189 Capra hircus
396728 Sus scrofa
493844 Felis catus
403587 Canis lupus familiaris
442996 Ovis aries
408185 Gallus gallus
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