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may be an intracellular kinase regulator. Additionally we are shipping GMFG Antibodies (49) and and many more products for this protein.
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These results indicate that the effects of GMFG on monocyte migration and adhesion probably occur through preventing ubiquitin-mediated proteasome degradation of alpha5beta1-integrin and facilitating effective beta1-integrin recycling back to the plasma membrane.
In this study, knockdown of GMF-gamma by RNA interference enhanced actin polymerization and contraction in human airway smooth muscle (HASM) cells and tissues without affecting myosin phosphorylation.
Together, the results suggest that GMFG functions by a mechanism similar to that of other ADF/cofilin (show CFL1 ELISA Kits) family members, displaying a preference for ADP-Arp2 (show ACTR2 ELISA Kits)/3 complex and undergoing inhibition by phosphorylation of a serine residue near the N terminus.
our findings suggest that GMFG functions as a negative regulator of TLR4 (show TLR4 ELISA Kits) signaling by facilitating TLR4 (show TLR4 ELISA Kits) endocytic trafficking in macrophages
characterized the promoter region and found the putative cis (show CISH ELISA Kits)-acting regulatory elements responsible for promoter activity
GMFG is a hematopoietic-specific protein that may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells
GMF debranches filaments by a mechanism related to cofilin-mediated severing, but in which GMF has evolved to target molecular junctions between actin-related proteins in the Arp2/3 complex and actin subunits in the daughter filament of the branch.
The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.
GMFG is a novel factor in actin cytoskeleton reorganization and is expressed preferentially in microvascular endothelial and inflammatory cells in embryonic development.
may be an intracellular kinase regulator
glia maturation factor, gamma
, glia maturation factor gamma
, Glia maturation factor gamma