Glial Cells Missing Homolog 1 (Drosophila) (GCM1) ELISA Kits

GCM1 encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). Additionally we are shipping GCM1 Antibodies (46) and GCM1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GCM1 GCM1 8521 Q9NP62
Anti-Mouse GCM1 GCM1 14531 P70348
Anti-Rat GCM1 GCM1 29394 Q9Z288
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More ELISA Kits for GCM1 Interaction Partners

Pig (Porcine) Glial Cells Missing Homolog 1 (Drosophila) (GCM1) interaction partners

  1. chromosomal localization of the porcine GCM1 gene and the identification and characterization of a GCM1 associated microsatellite marker [GCM1]

Human Glial Cells Missing Homolog 1 (Drosophila) (GCM1) interaction partners

  1. Identify a novel cis (show CISH ELISA Kits)-acting sequence (-369 to -320) at the placental growth factor (show PGF ELISA Kits) promoter, which was critical for mediating the basal and DLX3 (show DLX3 ELISA Kits)/GCM1-dependent PGF (show PGF ELISA Kits) promoter activities.

  2. Twist1 (show TWIST1 ELISA Kits) may promote trophoblast syncytialization by regulating the expression of GCM1.

  3. GATA3 (show GATA3 ELISA Kits) knockdown elevated HtrA4 (show HTRA4 ELISA Kits) expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 (show GATA3 ELISA Kits) function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion.

  4. GLI2 (show GLI2 ELISA Kits) stabilized glial cell missing-a, a pivotal transcriptional factor for trophoblastic syncytialization.

  5. Gcm1 and Fzd5 function in an evolutionary conserved positive feedback loop that regulates trophoblast differentiation and sites of chorionic branching morphogenesis.

  6. Results suggest that caspase-14 (show CASP14 ELISA Kits) may interact with GCM1 to participate in syncytiotrophoblast differentiation during placental development.

  7. study reveals a novel function for RACK1 (show GNB2L1 ELISA Kits) to regulate GCM1 activity and placental cell migration and invasion

  8. GCM1-directed villous trophoblast differentiation is repressed by DREAM

  9. c-Myc (show MYC ELISA Kits)-regulated members of the miR-17~92 and miR (show MLXIP ELISA Kits)-106a~363 clusters inhibit trophoblast differentiation by repressing GCM1 and CYP19A1 (show CYP19A1 ELISA Kits).

  10. Phorbol 12-myristate 13-acetate-induced protein kinase C (show PKC ELISA Kits) and mitogen-activated protein kinase kinase (show MAP2K1 ELISA Kits)/extracellular signal regulated kinase dependent pathway enhances the degradation as well as the transcriptional activity of GCMa.

Mouse (Murine) Glial Cells Missing Homolog 1 (Drosophila) (GCM1) interaction partners

  1. GCM1-directed villous trophoblast differentiation is repressed by DREAM

  2. Data show that the GCM1/syncytin-B pathway is significantly downregulated in the placenta of BCL9L (show BCL9L ELISA Kits)-deficient mice and that the fusion and differentiation of ST-II cells are blocked.

  3. as in mice, fetoplacental vascularity increased when GCM1 protein expression decreased (R(2)=-0.45; P<0.05).

  4. Gcm1 (glial cells missing 1) are involved in the epigenetic regulation of Hes5 (show HES5 ELISA Kits) transcription by DNA demethylation independently of DNA replication.

  5. studies identify a novel function of p45NF-E2 (show NFE2 ELISA Kits) during placental development: in trophoblast cells, p45NF-E2 (show NFE2 ELISA Kits) represses Gcm1 and syncytiotrophoblast formation via acetylation

  6. Gcm1 expression defines three stages of chorio-allantoic interaction during placental development

  7. Brief ectopic expression of Gcm1 in mouse embryonic tail bud induces failure of the neural tube to close (spina bifida) and multiple neural tubes (diastematomyelia).

  8. GCM domain as a new type of Zn-coordinating, sequence-specific DNA-binding domain.

  9. mGCMa expression is primarily postnatal, arguing for a role in organ function rather than organ development

  10. the shaping of the maternal blood spaces within the labyrinth was dependent on chorioallantoic morphogenesis and therefore disrupted in Gcm1 mutants

GCM1 Antigen Profile

Antigen Summary

This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.

Gene names and symbols associated with GCM1

  • glial cells missing homolog 1 (Drosophila) (GCM1) antibody
  • glial cells missing homolog 1 (Drosophila) (Gcm1) antibody
  • GCM antibody
  • GCM-1 antibody
  • Gcm-rs2 antibody
  • GCM1 antibody
  • Gcm1-rs1 antibody
  • Gcma antibody
  • glide antibody
  • hGCMa antibody

Protein level used designations for GCM1

glial cells missing homolog 1 (Drosophila) , chorion-specific transcription factor GCMa , glial cells missing-like protein 1 , glial cells missing homolog a , chorion-specific transcription factor GCMa-like , GCM motif protein 1 , Gcm 1 , Gcm a , glial cell deficient , mGCM1 , mGCMa

317779 Bos taurus
404300 Gallus gallus
414910 Sus scrofa
472036 Pan troglodytes
481844 Canis lupus familiaris
709965 Macaca mulatta
100056683 Equus caballus
100341874 Oryctolagus cuniculus
100403173 Callithrix jacchus
100452572 Pongo abelii
100465515 Ailuropoda melanoleuca
100581967 Nomascus leucogenys
8521 Homo sapiens
14531 Mus musculus
29394 Rattus norvegicus
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