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Glial Fibrillary Acidic Protein Proteins (GFAP)

GFAP encodes one of the major intermediate filament proteins of mature astrocytes. Additionally we are shipping GFAP Antibodies (707) and GFAP Kits (63) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GFAP 2670 P14136
GFAP 24387 P47819
GFAP 14580 P03995
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Top GFAP Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$598.40
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,193.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details

GFAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus) ,

Mouse (Murine) ,
, , ,

More Proteins for Glial Fibrillary Acidic Protein (GFAP) Interaction Partners

Rhesus Monkey Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. There was significantly more GFAP immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

Human Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. GFAP is upregulated following an insult or injury to the brain, additionally making it an indicator of CNS pathology.

  2. This study demonistrated that the density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

  3. This study demonstrated that GFAP as a promising biomarker to distinguish ischemic stroke from intracerebral hemorrhage.

  4. The levels of GFAP in Alzheimer's disease, dementia with Lewy bodies, and frontotemporal lobar degeneration patients were significantly higher than those in the healthy control subjects.

  5. GFAP is significantly associated with outcome, but it does not add predictive power to commonly used prognostic variables in a population of patients with TBI (show TBPL1 Proteins) of varying severities.

  6. Neither duplications nor deletions of GFAP were found, suggesting that GFAP coding-region rearrangements may not be involved in Alexander disease or Alexanderrelated leukoencephalopathies.

  7. The data suggest that human vitreous body GFAP is a protein biomarker for glial activation in response to retinal pathologies.

  8. Studied diagnostic Value of Serum Levels of GFAP, pNF-H, and NSE (show ENO2 Proteins) Compared With Clinical Findings in Severity Assessment of Human Traumatic Spinal Cord Injury.

  9. GFAP peaks early during haemorrhagic brain lesions (at significantly higher levels), and late in ischaemic events, whereas antibodies against NR2 RNMDA have significantly higher levels during ischemic stroke at all time-points.

  10. There was an absence of GFAP in astrocytes during early fetal spinal cord development until 9 months of gestation , and the appearance of GFAP-positive reactivity was later than that of neurons.

Pig (Porcine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Isolation of an evolutionary conserved novel GFAP isoform, GFAPkappa, produced by alternative splicing and polyadenylation of the 3'-region of the human GFAP pre-mRNA is described.

Mouse (Murine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. PINK1 (show PINK1 Proteins) deficiency causes defects in GFAP-positive astrogliogenesis during brain development.

  2. Gnasxl (show GNAS Proteins) deficiency does not directly affect glial development in the hypothalamus, since it is expressed in neurons, and Gfap-positive astrocytes and tanycytes appear normal during early postnatal stages.

  3. Induction of glial cytokine expression was sequential, aligned with active sickness behavior, and preceded increased Iba-1 (show AIF1 Proteins) or GFAP immunoreactivity after lipopolysaccharide challenge

  4. Study provides a mechanistic link between the GFAP mutations/overexpression and the symptoms in those affected with Type II Alexander disease

  5. Study described GFAP-expressing non-myelinating Schwann cells in the lung, validated a transgenic mouse line that drives expression of cre under a GFAP promoter

  6. findings thus show that the inability to produce GFAP and Vim (show VIM Proteins) affects normal retinal physiology and that the effect of IF deficiency on retinal cell survival differs, depending on the underlying pathologic condition

  7. CUL4B (show CUL4B Proteins) as a negative regulator of GFAP expression during neural development.

  8. Astrocytes deficient of GFAP and vimentin (show VIM Proteins) showed decreased Notch (show NOTCH1 Proteins) signal sending competence and altered expression of Notch (show NOTCH1 Proteins) signaling pathway-related genes

  9. Absence of GFAP, or both GFAP and vimentin (show VIM Proteins), alters Alzheimer's disease-induced changes in gene expression profile of astrocytes, showing a compensation of the decrease of neuronal support genes and a trend for a higher inflammatory expression profile

  10. immunohistochemistry revealed increased numbers of GFAP/BDNF (show BDNF Proteins) double-positive cells, which agrees with the observed changes in the culture system

Zebrafish Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. The distribution of GFAP immunoreactivity implies that enteric glia are widespread in the fish gastrointestinal tract.

  2. Generation of transgenic zebrafish that express green fluorescent protein (GFP) in glial cells driven by the zebrafish glial fibrillary acidic protein (GFAP) regulatory elements.

  3. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 Proteins), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

GFAP Protein Profile

Protein Summary

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with GFAP

  • glial fibrillary acidic protein (GFAP)
  • glial fibrillary acidic protein (LOC100136168)
  • glial fibrillary acidic protein (gfap)
  • glial fibrillary acidic protein (Gfap)
  • AI836096 protein
  • cb345 protein
  • etID36982.3 protein
  • GFAP protein
  • gfapl protein
  • wu:fb34h11 protein
  • wu:fk42c12 protein
  • xx:af506734 protein
  • zgc:110485 protein

Protein level used designations for GFAP

glial fibrillary acidic protein , glial fibrillary acidic protein alpha , intermediate filament , intermediate filament protein , zrf-1 antigen

GENE ID SPECIES
712941 Macaca mulatta
454741 Pan troglodytes
100136168 Oncorhynchus mykiss
100534495 Oreochromis niloticus
2670 Homo sapiens
24387 Rattus norvegicus
100720409 Cavia porcellus
101081938 Felis catus
396562 Sus scrofa
281189 Bos taurus
14580 Mus musculus
100352532 Oryctolagus cuniculus
419969 Gallus gallus
480495 Canis lupus familiaris
443220 Ovis aries
30646 Danio rerio
100172719 Pongo abelii
100033970 Equus caballus
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