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Glial Fibrillary Acidic Protein Proteins (GFAP)

GFAP encodes one of the major intermediate filament proteins of mature astrocytes. Additionally we are shipping GFAP Antibodies (802) and GFAP Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GFAP 2670 P14136
GFAP 24387 P47819
GFAP 14580 P03995
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Top GFAP Proteins at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$598.40
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 11 Days
$300.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,193.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details
Bovine Cow Un-conjugated   100 μg Log in to see 7 to 9 Days
$328.21
Details

GFAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus) ,
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Mouse (Murine) ,
, , ,

More Proteins for Glial Fibrillary Acidic Protein (GFAP) Interaction Partners

Rhesus Monkey Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. There was significantly more GFAP immunoreactivity in the prefrontal cortex and hippocampus of aged animals compared to adult or middle-aged animals.

Human Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Tat (show TAT Proteins) expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes.

  2. This study demonstrated that GFAP exhibited distinct temporal profiles over the course of 7 days in patient with traumatic brain injury.

  3. e data indicates that serum GFAP levels may be associated with severity of autism spectrum disorders among Chinese children.

  4. High GFAP expression is associated with retinoblastoma.

  5. Overall, glial fibrillary acidic protein reflected no evidence for significant peripartum brain injury in neonates with congenital heart defects, but there was a trend for elevation by postnatal day 4 in neonates with left heart obstruction.

  6. serum levels of GFAP were significantly lower in autism spectrum disorders than controls

  7. We found downregulation of GFAP mRNA and protein in the mediodorsal thalamus and caudate nucleus of depressed suicides compared with controls, whereas GFAP expression in other brain regions was similar between groups. Furthermore, a regional comparison including all samples revealed that GFAP expression in both subcortical regions was, on average, between 11- and 15-fold greater than in cerebellum and neocortex.

  8. GFAP is upregulated following an insult or injury to the brain, additionally making it an indicator of CNS pathology.

  9. This study demonistrated that the density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

  10. This study demonstrated that GFAP as a promising biomarker to distinguish ischemic stroke from intracerebral hemorrhage.

Pig (Porcine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. Isolation of an evolutionary conserved novel GFAP isoform, GFAPkappa, produced by alternative splicing and polyadenylation of the 3'-region of the human GFAP pre-mRNA is described.

Mouse (Murine) Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. work reveals that an Alexander disease-causing mutation alters GFAP turnover kinetics in vivo and provides an essential foundation for future studies aimed at preventing or reducing the accumulation of GFAP.

  2. Tat (show TAT Proteins) expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes.

  3. Study provides evidence that transcription of one of the astrocyte-specific genes, Gfap, is cooperatively regulated by co-expressed genes and their regulatory factors.

  4. This study demonstrated the GFAP-ApoE4 mice exhibited motor impairments when compared to GFAP-ApoE3 and wild-type mice.

  5. PINK1 (show PINK1 Proteins) deficiency causes defects in GFAP-positive astrogliogenesis during brain development.

  6. Gnasxl (show GNAS Proteins) deficiency does not directly affect glial development in the hypothalamus, since it is expressed in neurons, and Gfap-positive astrocytes and tanycytes appear normal during early postnatal stages.

  7. Induction of glial cytokine expression was sequential, aligned with active sickness behavior, and preceded increased Iba-1 (show AIF1 Proteins) or GFAP immunoreactivity after lipopolysaccharide challenge

  8. Study provides a mechanistic link between the GFAP mutations/overexpression and the symptoms in those affected with Type II Alexander disease

  9. Study described GFAP-expressing non-myelinating Schwann cells in the lung, validated a transgenic mouse line that drives expression of cre under a GFAP promoter

  10. findings thus show that the inability to produce GFAP and Vim (show VIM Proteins) affects normal retinal physiology and that the effect of IF deficiency on retinal cell survival differs, depending on the underlying pathologic condition

Zebrafish Glial Fibrillary Acidic Protein (GFAP) interaction partners

  1. The distribution of GFAP immunoreactivity implies that enteric glia are widespread in the fish gastrointestinal tract.

  2. Generation of transgenic zebrafish that express green fluorescent protein (GFP) in glial cells driven by the zebrafish glial fibrillary acidic protein (GFAP) regulatory elements.

  3. Cells expressing the two reporters display radial glial morphology, colocalize with the NSC marker Sox2 (show SOX2 Proteins), undergo proliferation, and are capable of self-renewal within the matrix of distinct thickness in the telencephalon.

GFAP Protein Profile

Protein Summary

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with GFAP

  • glial fibrillary acidic protein (GFAP)
  • glial fibrillary acidic protein (LOC100136168)
  • glial fibrillary acidic protein (gfap)
  • glial fibrillary acidic protein (Gfap)
  • AI836096 protein
  • cb345 protein
  • etID36982.3 protein
  • GFAP protein
  • gfapl protein
  • wu:fb34h11 protein
  • wu:fk42c12 protein
  • xx:af506734 protein
  • zgc:110485 protein

Protein level used designations for GFAP

glial fibrillary acidic protein , glial fibrillary acidic protein alpha , intermediate filament , intermediate filament protein , zrf-1 antigen

GENE ID SPECIES
712941 Macaca mulatta
454741 Pan troglodytes
100136168 Oncorhynchus mykiss
100534495 Oreochromis niloticus
2670 Homo sapiens
24387 Rattus norvegicus
100720409 Cavia porcellus
101081938 Felis catus
396562 Sus scrofa
281189 Bos taurus
14580 Mus musculus
100352532 Oryctolagus cuniculus
419969 Gallus gallus
480495 Canis lupus familiaris
443220 Ovis aries
30646 Danio rerio
100172719 Pongo abelii
100033970 Equus caballus
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