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The protein encoded by GCG is actually a preproprotein that is cleaved into four distinct mature peptides. Additionally we are shipping Glucagon Kits (65) and Glucagon Proteins (31) and many more products for this protein.
Showing 10 out of 321 products:
Human Monoclonal GCG Primary Antibody for ELISA, WB - ABIN395510
Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. in Diabetes 2010
Show all 5 references for ABIN395510
Human Polyclonal GCG Primary Antibody for EIA, FACS - ABIN453051
Jacobo, Guerra, Jarrard, Przybyla, Liu, Watts, Hockerman: The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts. in The Journal of pharmacology and experimental therapeutics 2009
Show all 2 references for ABIN453051
Human Monoclonal GCG Primary Antibody for IF, IHC (p) - ABIN111416
Eissele, Göke, Willemer, Harthus, Vermeer, Arnold, Göke: Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. in European journal of clinical investigation 1992
Show all 2 references for ABIN111416
Human Polyclonal GCG Primary Antibody for FACS, IF - ABIN390769
Brennan, Feltrin, Nair, Hausken, Little, Gentilcore, Wishart, Jones, Horowitz, Feinle-Bisset: Effects of the phases of the menstrual cycle on gastric emptying, glycemia, plasma GLP-1 and insulin, and energy intake in healthy lean women. in American journal of physiology. Gastrointestinal and liver physiology 2009
Human Monoclonal GCG Primary Antibody for IHC (p), IP - ABIN1107373
Schroeder, Lopez, Harper, Saunders: Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37. in Cytogenetics and cell genetics 1984
Human Polyclonal GCG Primary Antibody for IHC (fro), IF - ABIN113443
Brar, Brinster, Frohman: Immunohistochemical analysis of human growth hormone-releasing hormone gene expression in transgenic mice. in Endocrinology 1989
Human Polyclonal GCG Primary Antibody for WB - ABIN2777108
Laakso, Zilinskaite, Hansen, Boesgaard, Vänttinen, Stancáková, Jansson, Pellmé, Holst, Kuulasmaa, Hribal, Sesti, Stefan, Fritsche, Häring, Pedersen, Smith: Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study. in Diabetologia 2008
Human Polyclonal GCG Primary Antibody for EIA - ABIN318561
Woods, Lutz, Geary, Langhans: Pancreatic signals controlling food intake; insulin, glucagon and amylin. in Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2006
Chicken Polyclonal GCG Primary Antibody for WB - ABIN2777107
Meier, Nauck, Pott, Heinze, Goetze, Bulut, Schmidt, Gallwitz, Holst: Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans. in Gastroenterology 2006
The findings indicate that the brainstem preproglucagon neuronal system is highly conserved between rat and non-human primate
Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities in cultured cardiomyocytes.
GLP-1 release is altered in intestinal cultures from a high fat diet-fed mice.
Data show that ginsenoside Rg3 stimulated glucagon-like peptide-1 (GLP-1) secretion in NCI-H716 enteroendocrine cells.
GPR119 (show GPR119 Antibodies) in L-cells plays a key role in oral lipid-triggered GLP-1 secretion.
Galanin (show GAL Antibodies), acting via the GAL1 (show LGALS1 Antibodies) receptor and Gi -coupled signalling in L and K cells, is a potent inhibitor of GLP-1 and GIP (show GIP Antibodies) secretion
AMPK (show PRKAA1 Antibodies) antagonizes hepatic glucagon signalling via phosphorylation-induced PDE4B (show PDE4B Antibodies) activation
The stress-induced Brg1 (show SMARCA4 Antibodies)-G9a (show EHMT2 Antibodies)/GLP (show GOLGA6A Antibodies)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Antibodies) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.
Data suggest that pharmacological stimulation of serotonin 5Ht1b (show HTR1B Antibodies) receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1) induced by Dpp4 (dipeptidylpeptidase 4 (show DPP4 Antibodies)) inhibition independently of feeding and also improves glucose tolerance.
Deletion of AMPK alpha 1 (show PRKAA1 Antibodies) and alpha 2 in proglucagon-expressing cells results in increased L-cell mass and elevated circulating GLP-1 levels.
The results suggest that TGR5 (show GPBAR1 Antibodies) activation mediates cross-talk between alpha- and beta-cells by switching from glucagon to GLP-1 to restore beta- cell mass and function under hyperglycemic conditions.
The GLP-1 secretion after 75 g OGTT was impaired in newly diagnosed T2DM patients, inversely proportional to insulin (show INS Antibodies) resistance and hyperglycemia, and positively correlated with beta-cell function and insulin (show INS Antibodies) sensitivity.
Selective degradation of the mutant EHMT1 (show EHMT1 Antibodies) mRNA leads to Kleefstra syndrome.
G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies) are required for stable maintenance of imprinted DNA methylation (show HELLS Antibodies) in embryonic stem cells.
the clinical picture we found in Norwegian patients with Kleefstra syndrome is similar to the findings described in the literature. An interesting point is that in the literature >85% of the patients have a deletion of 9q34.3 and the remaining have a mutation in the EHMT1 (show EHMT1 Antibodies) gene, whereas in this study we found 50% with a deletion, and 50% with a mutation.
GLP-1 secretion increased in response to inflammatory stimuli in humans, which was associated to parameters of glucose metabolism and best predicted by IL6 (show IL6 Antibodies).
Among young and healthy adults, GLP-1 levels are strongly and independently related to body fat mass especially in men, but not body mass index or waist circumference.
Glucagon circulates in patients without a pancreas and glucose stimulation of the gastrointestinal tract elicits significant hyperglucagonemia in these patients.
There is minor contribution of endogenous GLP-1 and GLP-2 to postprandial lipemia in obese men.
Data suggest that endocrine responses differ between jejunal and gastric enteral feeding, with higher peak plasma CCK (cholecystokinin), PYY (peptide YY), and GLP-1/2 (glucagon-like peptides 1/2) concentrations being attained after jejunal feeding.
Data suggest that capsaicin, an appetite suppressant dietary supplement (here, administered via intraduodenal infusion), does not act via alteration of secretion of satiety hormones GLP-1 (GLP-1) and PYY (peptide YY).
data demonstrate that cattle express proglucagon and glucagon-like peptide 2 receptor (show GLP2R Antibodies) mRNA primarily in small intestinal and colon tissues and increased nutrient intake increases ileal proglucagon mRNA and plasma glucagon-like peptide 2
The patterns of colocalization of the K cell marker, glucagon-like insulinotropic peptide, and L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated.
Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Able to repress GATA transcription factor function (By similarity).
, preproglucagon B
, G9a-like protein 1
, euchromatic histone-lysine N-methyltransferase 1
, histone-lysine N-methyltransferase EHMT1
, lysine N-methyltransferase 1D
, G9a like protein
, H3-K9-HMTase 5
, histone H3-K9 methyltransferase 5
, histone-lysine N-methyltransferase, H3 lysine-9 specific 5
, glicentin-related polypeptide
, glucagon-like peptide 1
, glucagon-like peptide 2
, glucagon-like peptide I
, glucagon-like peptide-1
, glucagon I
, proglucagon I
, glucagon preproprotein
, preproglucagon A
, G protein-coupled receptor GLP2R
, GLP-2 receptor
, GLP II
, granzyme-like protein 2
, granzyme-like protein II
, mast cell protease X
, GATA like protein 1
, GATA like protein-1
, GATA zinc finger domain containing 3
, GATA-like protein 1
, GATA-type zinc finger protein 1