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Glucosamine-6-phosphate deaminase (EC 22.214.171.124) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003. Additionally we are shipping Glucosamine-6-Phosphate Deaminase 1 Antibodies (89) and Glucosamine-6-Phosphate Deaminase 1 Proteins (13) and many more products for this protein.
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The silencing of PGI/AMF (show GPI ELISA Kits) decreased the levels of phosphorylated Akt (show AKT1 ELISA Kits) (-71.9%, P<0.001) compared with the scrambled siRNA, as well as the levels of the stemness marker, SOX2 (show SOX2 ELISA Kits) (-61.7%, P<0.01). Taken together, these findings suggest that PGI/AMF (show GPI ELISA Kits) silencing decreases migration, tumorsphere formation as well as the proportion of on the side population cells in glioblastoma U87 cells.
NLK (show NLK ELISA Kits) is able to promote cell proliferation and type II collagen (show COL2A1 ELISA Kits) synthesis during in vitro chondrocyte propagation.
Suggest tha AMF/PGI (show GPI ELISA Kits)-mediated tumorigenesis occurs through MAPK-ERK (show MAPK1 ELISA Kits) signaling in endometrial carcinoma.
Study supports a role for AMF (show GPI ELISA Kits) mediating epithelial-mesenchymal transition in endometrial cancer (EC) through MAPK (show MAPK1 ELISA Kits) signaling. Therefore, AMF (show GPI ELISA Kits) may provide a potential prognostic and therapeutic target in preventing EC progression.
Results showed an increase in GPI and AMFR (show AMFR ELISA Kits) in clear cell-renal cell carcinoma cells, and their colocalization on plasma membrane. Kaplan-Meier curves showed significant differences in survival among groups of patients with high versus low GPI.
The association of ENO1 (show ENO1 ELISA Kits) and GPI with postthaw sperm viability and motility was confirmed using Pearson's linear correlation. ENO1 (show ENO1 ELISA Kits) and GPI can be used as markers of human sperm freezability before starting the cryopreservation procedure.
High GPI expression is associated with metastatic phenotype of breast cancer.
PGI (show BGN ELISA Kits) is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.
Serum anti-GPI autoantibodies are useful for the diagnosis of rheumatoid arthritis in Chinese patients.
Findings suggest that autocrine motility factor (AMF (show GPI ELISA Kits))-HER2 (show ERBB2 ELISA Kits) interaction might be a novel target for therapeutic management of patients with breast cancer, whose disease is resistant to trastuzumab.
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
glucosamine-6-phosphate deaminase 1
, glucosamine-6-phosphate isomerase 1
, Glucosamine-6-phosphate deaminase 1
, GNPDA 1
, glcN6P deaminase 1
, putative glucosamine-6-phosphate isomerase
, putative Glucosamine-6-phosphate isomerase
, glucose-6-phosphate isomerase
, autocrine motility factor
, glucose phosphate isomerase
, hexose monophosphate isomerase
, hexosephosphate isomerase
, phosphoglucose isomerase
, phosphohexose isomerase
, sperm antigen 36
, sperm antigen-36