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Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) Proteins (GCNT2)

GCNT2 encodes the enzyme responsible for formation of the blood group I antigen. Additionally we are shipping GCNT2 Antibodies (53) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GCNT2 14538  
Rat GCNT2 GCNT2 306860  
GCNT2 2651 Q8N0V5,Q06430,Q8NFS9
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Top GCNT2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GCNT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,

More Proteins for Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) Interaction Partners

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. These data clearly suggest that GCNT2 functions in vivo together with beta3GnT2 to determine poly-N-acetyllactosamine (PLN (show PLN Proteins)) levels in olfactory neurons by regulating beta1,6-branches that promote PLN (show PLN Proteins) extension.

  2. conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I (show GCNT1 Proteins) form a network of disulfide bonds and include a thiol that affects enzyme activity

  3. molecular cloning and analysis of expression of mouse mucus-type core 2 beta1,6 N-acetylglucosaminyltransferase (show GCNT1 Proteins)

  4. Leukocyte core2GlcNAc transferase is required for biosynthesis of functional L-selectin (show SELL Proteins) ligands in inflamed venules of mouse cremaster muscle.

Human Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2) interaction partners

  1. GCNT2 expression is closely associated with invasive potential of prostate cancer.

  2. Hypomethylation of the GCNT2 variant 2 reflected lymph node metastasis of colorectal cancer in the tumor and normal tissues.

  3. An Alu repeat-mediated genomic GCNT2 deletion underlies congenital cataracts and adult i blood group (show DARC Proteins)

  4. Results show involvement of GCNT2 in EMT (show ITK Proteins) and TGF-beta (show TGFB1 Proteins) signaling, and further glycosylation modification of E-cadherin (show CDH1 Proteins) by GCNT2, are the underlying integrative mechanisms for breast cancer metastasis.

  5. In the family with the "ii" blood group a novel GCNT2 mutation was found in the cataract patients.

  6. A nonsense mutation in the GCNT2 gene isoforms is associated with autosomal recessive congenital cataract in four distantly related Arab families from Israel.

  7. role of C/EBPalpha (show CEBPA Proteins) in the induction of the IGnTC gene as well as in I antigen expression

GCNT2 Protein Profile

Protein Summary

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with GCNT2

  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Gcnt2)
  • glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2)
  • 5330430K10Rik protein
  • bA360O19.2 protein
  • bA421M1.1 protein
  • CCAT protein
  • CTRCT13 protein
  • GCNT2C protein
  • GCNT5 protein
  • IGNT protein
  • IGnTA protein
  • IGnTB protein
  • IGnTC protein
  • II protein
  • NACGT1 protein
  • NAGCT1 protein
  • ULG3 protein

Protein level used designations for GCNT2

I-branching enzyme , N-acetylglucosaminyltransferase , N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase , beta-1,6-N-acetylglucosaminyltransferase , glucosaminyltransferase, I-branching enzyme , large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase , I-branching beta-1,6-acetylglucosaminyltransferase , I beta-1,6-N-acetylglucosaminyltransferase , Ii blood group , beta-1,6-N-acetylglucosaminyltransferase 2

GENE ID SPECIES
14538 Mus musculus
306860 Rattus norvegicus
2651 Homo sapiens
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