Glucose 6-Phosphatase, Catalytic 3 Proteins (G6PC3)

G6PC3 encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). Additionally we are shipping G6PC3 Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
G6PC3 92579 Q9BUM1
G6PC3 68401 Q6NSQ9
Rat G6PC3 G6PC3 303565 Q6AZ83
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top G6PC3 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

G6PC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Glucose 6-Phosphatase, Catalytic 3 (G6PC3) Interaction Partners

Human Glucose 6-Phosphatase, Catalytic 3 (G6PC3) interaction partners

  1. classic features of SCN (show SRI Proteins) IV found to share an identical inherited canonical splice-site mutation of the G6PC3 gene (c.218+1G>A).

  2. Multilineage involvement of immune system occurs in G6PC3 deficiency in addition to the previously described neutropenia and multiple abnormalities.

  3. G6PC3 defects should be considered in any case of congenital, unexplained neutropenia regardless of the clinical phenotype.

  4. functional characterization of 16 of the 19 known missense mutations in severe congenital neutropenia syndrome caused by glucose-6-phosphatase-beta deficiency;14 missense mutations completely abolish G6Pase-beta activity while the p.S139I and p.R189Q mutations retain 49% and 45%, respectively of wild type activity

  5. Severe congenital neutropenia with autosomal recessive G6PC3 mutations is associated with considerable clinical heterogeneity.

  6. A role for G6PC3 in testicular differentiation and formation.

  7. G6PC3 mutation is associated with severe congenital neutropenia.

  8. Glucose 6 phosphatase catalytic subunit-3 deficiency due to mutation is a heterogenous disorder characterized by severe congenital neutropenia.

  9. Biallelic G6PC3 defects should be considered in patients with autosomal recessive cyclic neutropenia, especially those with typical associated congenital defects.

  10. review of clinical, molecular and genetic aspects of G6PC3 deficiency; loss of function in missense G6PC3 mutations likely results from decreased enzyme stability; the condition can be diagnosed by sequencing G6PC3 gene; a number of G6PC3 ounder mutations are known in various populations and possible genotype-phenotype relationship also exists

Mouse (Murine) Glucose 6-Phosphatase, Catalytic 3 (G6PC3) interaction partners

  1. Survival and differentiation defects contribute to neutropenia in glucose-6-phosphatase-beta (G6PC3) deficiency in a model of mouse neutrophil granulocyte differentiation.

  2. G-CSF (show CSF3 Proteins) improves G6pc3(-/-) neutrophil survival by modulating apoptotic mediators and rectifies function by enhancing energy homeostasis.

  3. in nonapoptotic neutrophils, G6PC3 is essential for normal energy homeostasis. A G6PC3 deficiency prevents recycling of ER glucose to the cytoplasm, leading to neutrophil dysfunction

  4. UGRP/G6Pase (show G6PC Proteins) is the major glucose-6-phosphatase (show G6PC Proteins) of physiological importance for glucose homeostasis in vivo.

  5. The absence of G6Pase-beta led to neutropenia

G6PC3 Protein Profile

Protein Summary

This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.

Gene names and symbols associated with G6PC3

  • glucose 6 phosphatase, catalytic, 3 (G6PC3)
  • glucose 6 phosphatase, catalytic, 3 (G6pc3)
  • 0710001K01Rik protein
  • AU019276 protein
  • AU045429 protein
  • AV128920 protein
  • AW545836 protein
  • SCN4 protein
  • UGRP protein

Protein level used designations for G6PC3

G-6-Pase 3 , G6Pase 3 , G6Pase-beta , glucose-6-phosphatase 3 , glucose-6-phosphatase catalytic subunit 3 , ubiquitous glucose-6-phosphatase catalytic subunit-related protein , ubiquitously expressed G6Pase catalytic subunit-related protein , glucose-6-phosphatase catalytic subunit-related

92579 Homo sapiens
68401 Mus musculus
303565 Rattus norvegicus
369023 Bos taurus
Selected quality suppliers for G6PC3 Proteins (G6PC3)
Did you look for something else?