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Glucose-6-Phosphate Isomerase Proteins (GPI)

GPI belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. Additionally we are shipping Glucose-6-Phosphate Isomerase Antibodies (226) and Glucose-6-Phosphate Isomerase Kits (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPI 26384 O88958
GPI 2821 P06744
GPI 292804 Q6P6V0
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Top Glucose-6-Phosphate Isomerase Proteins at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 11 Days
$308.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$683.10
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Calanus finmarchicus His tag   1 mg Log in to see 56 to 66 Days
$2,808.67
Details

GPI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human , ,
, ,
Rat (Rattus)

Top referenced Glucose-6-Phosphate Isomerase Proteins

  1. Human GPI Protein expressed in Escherichia coli (E. coli) - ABIN2181186 : Zhang, Haga, Sekiguchi, Hirano: Structure of insect chitin isolated from beetle larva cuticle and silkworm (Bombyx mori) pupa exuvia. in International journal of biological macromolecules 2000 (PubMed)
    Show all 5 references for ABIN2181186

  2. Human GPI Protein expressed in Escherichia coli (E. coli) - ABIN666778 : Lin, Kao, Chen, Meng: Effects of inherited mutations on catalytic activity and structural stability of human glucose-6-phosphate isomerase expressed in Escherichia coli. in Biochimica et biophysica acta 2009 (PubMed)
    Show all 2 references for ABIN666778

  3. Human GPI Protein expressed in Escherichia coli (E. coli) - ABIN1047072 : Yakirevich, Naot: Cloning of a glucose phosphate isomerase/neuroleukin-like sperm antigen involved in sperm agglutination. in Biology of reproduction 2000 (PubMed)

More Proteins for Glucose-6-Phosphate Isomerase (GPI) Interaction Partners

Mouse (Murine) Glucose-6-Phosphate Isomerase (GPI) interaction partners

  1. PGI (show BGN Proteins) is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.

  2. The mGPI-transgenic mice presented GPI more efficiently and showed a dramatic increase in negative selection and an inhibition of arthritis.

  3. Increased red cell turnover in a line of CD22 (show CD22 Proteins)-deficient mice is caused by Gpi1c: a model for hereditary haemolytic anaemia.

  4. Data show that silencing of AMF/PGI induced MET and suppressed the tumor growth and pulmonary metastasis of LM8 cells in nude mice.

  5. induces hyperpermeability of endothelial and mesothelial cells leading to accumulation of ascites fluid (tumor autocrine motility factor)

  6. acid-induced conformational changes in phosphoglucose isomerase result in its increased cell surface association and deposition on fibronectin (show FN1 Proteins) fibrils

  7. Gpi1 (show PIGQ Proteins) immunoreactivity was found in ganglion, amacrine, horizontal and bipolar cells, but not in rods, cones, pigment epithelium and Muller cells.

  8. crystal structure of Autocrine Motility Factor

  9. AMF expression significantly contributes to the aggressive phenotype of pancreatic cancer

  10. Results report the first high-resolution crystal structure of the inhibitor-free form and the eight types of inhibitor complexes of mouse autocrine motility factor.

Human Glucose-6-Phosphate Isomerase (GPI) interaction partners

  1. NLK (show NLK Proteins) is able to promote cell proliferation and type II collagen (show COL2A1 Proteins) synthesis during in vitro chondrocyte propagation.

  2. Suggest tha AMF/PGI-mediated tumorigenesis occurs through MAPK-ERK (show MAPK1 Proteins) signaling in endometrial carcinoma.

  3. Study supports a role for AMF mediating epithelial-mesenchymal transition in endometrial cancer (EC) through MAPK (show MAPK1 Proteins) signaling. Therefore, AMF may provide a potential prognostic and therapeutic target in preventing EC progression.

  4. Results showed an increase in GPI (show GNPDA1 Proteins) and AMFR (show AMFR Proteins) in clear cell-renal cell carcinoma (show MOK Proteins) cells, and their colocalization on plasma membrane. Kaplan-Meier curves showed significant differences in survival among groups of patients with high versus low GPI (show GNPDA1 Proteins).

  5. The association of ENO1 (show ENO1 Proteins) and GPI (show GNPDA1 Proteins) with postthaw sperm viability and motility was confirmed using Pearson's linear correlation. ENO1 (show ENO1 Proteins) and GPI (show GNPDA1 Proteins) can be used as markers of human sperm freezability before starting the cryopreservation procedure.

  6. High GPI (show GNPDA1 Proteins) expression is associated with metastatic phenotype of breast cancer.

  7. PGI (show BGN Proteins) is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.

  8. Serum anti-GPI (show GNPDA1 Proteins) autoantibodies are useful for the diagnosis of rheumatoid arthritis in Chinese patients.

  9. Findings suggest that autocrine motility factor (AMF)-HER2 (show ERBB2 Proteins) interaction might be a novel target for therapeutic management of patients with breast cancer, whose disease is resistant to trastuzumab.

  10. For PGI (show BGN Proteins), an extended active site in which residues in the first, second, and third layers around the reacting substrate are predicted.

Glucose-6-Phosphate Isomerase (GPI) Protein Profile

Protein Summary

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Gene names and symbols associated with GPI

  • glucose-6-phosphate isomerase (GPI)
  • Phosphoglucose isomerase (Pgi)
  • gpi (pgi)
  • glucose-6-phosphate isomerase (gpi)
  • gpi Glucose-6-phosphate isomerase (gpi)
  • glucosamine-6-phosphate deaminase 1 (Gnpda1)
  • glucose phosphate isomerase 1 (Gpi1)
  • glucose-6-phosphate isomerase (Gpi)
  • AMF protein
  • CG8251 protein
  • DDBDRAFT_0185620 protein
  • DDBDRAFT_0231026 protein
  • DDB_0185620 protein
  • DDB_0231026 protein
  • Dmel\\CG8251 protein
  • Gnp1 protein
  • GNPDA protein
  • GNPI protein
  • Gpi protein
  • Gpi-1 protein
  • Gpi-1r protein
  • Gpi-1s protein
  • Gpi-1t protein
  • Gpi1 protein
  • Gpi1-r protein
  • Gpi1-s protein
  • Gpi1-t protein
  • Gpi1s protein
  • MF protein
  • NK protein
  • NK/GPI protein
  • NLK protein
  • Org protein
  • oscillin protein
  • pgi protein
  • PHI protein
  • SA-36 protein
  • SA36 protein

Protein level used designations for GPI

CG8251-PA , CG8251-PB , CG8251-PC , Pgi-PA , Pgi-PB , Pgi-PC , glucose phosphate isomerase , phosphoglucoisomerase , phosphoglucose isomerase , glucose-6-phosphate isomerase , gpi Glucose-6-phosphate isomerase , GNPDA 1 , glcN6P deaminase 1 , glucosamine-6-phosphate isomerase 1 , NLK , PGI , PHI , autocrine motility factor , glucose phosphate isomerase 1 complex , glucose phosphate isomerase 1, regulatory , glucose phosphate isomerase 1, structural , glucose phosphate isomerase 1, temporal , maturation factor , neuroleukin , phosphohexose isomerase , structural glucose phosphate isomerase 1 , hexose monophosphate isomerase , hexosephosphate isomerase , oxoisomerase , phosphohexomutase , phosphosaccharomutase , sperm antigen 36 , sperm antigen-36 , AMF , muscle phosphohexose isomerase , glucosephosphate isomerase

GENE ID SPECIES
100057160 Equus caballus
35886 Drosophila melanogaster
543945 Solanum lycopersicum
692243 Hordeum vulgare
780596 Triticum aestivum
1022330 Bifidobacterium longum NCC2705
1089499 Tropheryma whipplei str. Twist
3116331 Legionella pneumophila str. Lens
3117706 Legionella pneumophila str. Paris
7997113 Bartonella grahamii as4aup
8624197 Dictyostelium discoideum AX4
8691155 Bifidobacterium dentium Bd1
26384 Mus musculus
14751 Mus musculus
2821 Homo sapiens
397602 Sus scrofa
611942 Canis lupus familiaris
292804 Rattus norvegicus
280808 Bos taurus
100008744 Oryctolagus cuniculus
100719769 Cavia porcellus
415783 Gallus gallus
100174006 Pongo abelii
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