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anti-Glucuronidase, beta (GUSB) Antibodies

GUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. Additionally we are shipping Glucuronidase beta Kits (48) and Glucuronidase beta Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GUSB 2990 P08236
GUSB 110006 P12265
GUSB 24434 P06760
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Top anti-Glucuronidase beta Antibodies at antibodies-online.com

Showing 10 out of 119 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-GUSB Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of WiDr cells using Beta-glucuronidase Antibody (Center) Cat.-No AP51986PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human colon carcinoma reacted with Beta-glucuronidase Antibody (Center) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GUSB Antibody (Center) (ABIN653297) in WiDr, A2058, K562 cell line lysates (35 µg/lane). GUSB (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma reacted with GUSB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB GUSB Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the GUSB antibody detected the GUSB protein (arrow). GUSB Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GUSB Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with Beta-glucuronidase Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of Beta-glucuronidase Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the GUSB antibody detected the GUSB protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Anti-beta glucuronidase(GUSB) antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SW620 Cell Lysate Lane 3: MCF-7 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC, WB Lane: HepG2 cell lysate. Antibody titration: 2.5ug/ml Paraffin-embedded human lung. Cells with positive label: alveolar cells. Antibody concentration: 4-8 ug/ml 100 μg Log in to see 8 to 10 Days
$493.17
Details
REACT_Escherichia coli Mouse Un-conjugated EIA   1 mg Log in to see 6 to 8 Days
$456.50
Details
Dog Rabbit Un-conjugated WB Western blot analysis of Beta-glucuronidase expression in K562 (A), HeLa (B), HepG2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

GUSB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Glucuronidase beta Antibodies

  1. Human Polyclonal Glucuronidase beta Primary Antibody for EIA, FACS - ABIN950654 : Tomatsu, Montaño, Dung, Grubb, Sly: Mutations and polymorphisms in GUSB gene in mucopolysaccharidosis VII (Sly Syndrome). in Human mutation 2009 (PubMed)
    Show all 2 references for ABIN950654

  2. Chicken Polyclonal Glucuronidase beta Primary Antibody for IHC, WB - ABIN2781774 : Urayama, Grubb, Sly, Banks: Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

  3. Human Polyclonal Glucuronidase beta Primary Antibody for ELISA, WB - ABIN1451070 : Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: The DNA sequence of human chromosome 7. ... in Nature 2003 (PubMed)

More Antibodies against Glucuronidase beta Interaction Partners

Horse (Equine) Glucuronidase, beta (GUSB) interaction partners

  1. The aim of this study was to compare the levels of electrolytes, inorganic phosphatase, and alkaline phosphatease, acid phosphatase, and beta-glucuronidase.

Human Glucuronidase, beta (GUSB) interaction partners

  1. the efficacy of a helper-dependent (HD) canine adenovirus (CAV-2 (show CAV2 Antibodies)) vector harboring a human GUSB expression cassette (HD-RIGIE) in the MPS VII (show TH Antibodies) dog brain was tested

  2. This assessment demonstrated that although butyrate dramatically increased beta-glucuronidase production in bioreactors, it adversely impacted the mannose-6-phosphorylation of this lysosomal storage diseasestherapeutic enzyme

  3. expression of CES2, UGTA1A1, and GUSB varies in colorectal pathology tissues and that the expression of CES2 is somewhat related to tumor staging.

  4. GUSB and ATP2B4 (show ATP2B4 Antibodies) have been validated as a reliable gene combination for Cystic Fibrosis Transmembrane Conductance Regulator (show CFTR Antibodies) gene qPCR data normalization.

  5. Liver disease affects the expression of common HKGs; beta-glucuronidase and splicing factor arginine/serine-rich 4 (show SRSF4 Antibodies) are the most stable HKGs for studies of gene expression in HCV-infected human liver.

  6. beta-glucuronidase mutations are associated with mucopolysaccharidosis type VII (show TH Antibodies)

  7. Recombinant adeno (show ADORA2A Antibodies)-associated virus encoding human GUSB injected into the vitreous humor of young adult MPS VII (show TH Antibodies) mice increased GUSB activity and reduced lysosomal distension in regions of the thalamus and tectum

  8. beta glucuronidase present in the synovial fluid of rheumatoid arthritis patients, may contribute to the depletion of glycosaminoglycans from cartilage allowing invasion of synovial cells.

  9. Over-expression of beta-glucuronidase was related to the degree of cancer differentiation, but not to lymph node metastasis.

  10. These results indicate that beta-glucuronidase transport into brain parenchyma in early postnatal life is mediated by the mannose 6-phosphate/insulin-like growth factor II receptor (show IGF2R Antibodies).

Mouse (Murine) Glucuronidase, beta (GUSB) interaction partners

  1. beta-Glucuronidase, a Regulator of Lyme Arthritis Severity, Modulates Lysosomal Trafficking and MMP-9 (show MMP9 Antibodies) Secretion in Response to Inflammatory Stimuli

  2. GUSB modulates arthritis pathogenesis by preventing accumulation of proinflammatory glycosaminoglycans within inflamed joint tissue.

  3. The Gus plays a role in liver retinoid metabolism.

  4. Missense mutations and models of murine mucopolysaccharidosis type VII (show TH Antibodies) produced by targeted mutagenesis

  5. data indicate the expression of beta-glucuronidase coordinated with testosterone level in male CBA mice but not C57BL/6 mice

  6. Lysosome storage in the mucopoysaccharidosis type VII (show TH Antibodies) brain was corrected by injection of an HSV-1 genetic vector and expression of Gusb was assayed. genetic vector

Cow (Bovine) Glucuronidase, beta (GUSB) interaction partners

  1. AnxA6 (show ANXA6 Antibodies) is a novel receptor that mediates the endocytosis of bovine beta-glucuronidase.

Glucuronidase beta (GUSB) Antigen Profile

Protein Summary

This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. There are many pseudogenes of this locus in the human genome.

Gene names and symbols associated with GUSB

  • glucuronidase, beta (GUSB) antibody
  • beta-D-glucuronidase (bglR) antibody
  • Beta-glucuronidase (gusB) (gusB) antibody
  • beta glucuronidase (Glu) antibody
  • glucuronidase, beta (Gusb) antibody
  • glucuronidase, beta (gusb) antibody
  • glucuronidase, beta-like (LOC100347788) antibody
  • Ac2-223 antibody
  • AI747421 antibody
  • asd antibody
  • beta-GUS antibody
  • BG antibody
  • g antibody
  • Gur antibody
  • Gus antibody
  • Gus-r antibody
  • Gus-s antibody
  • Gus-t antibody
  • Gus-u antibody
  • GUSB antibody
  • Gut antibody
  • MPS7 antibody
  • si:ch211-160e1.7 antibody
  • si:ct573103.7 antibody

Protein level used designations for GUSB

glucuronidase, beta , beta-D-glucuronidase , Beta-glucuronidase (gusB) , beta-glucuronidase , beta-G1 , adipose storage deficiency

GENE ID SPECIES
463443 Pan troglodytes
988388 Clostridium perfringens str. 13
1453057 Sulfolobus solfataricus P2
5656922 Drosophila melanogaster
100037416 Equus caballus
100173726 Pongo abelii
2990 Homo sapiens
110006 Mus musculus
24434 Rattus norvegicus
571441 Danio rerio
427823 Gallus gallus
403831 Canis lupus familiaris
100144519 Sus scrofa
515687 Bos taurus
100733204 Cavia porcellus
493879 Felis catus
100347788 Oryctolagus cuniculus
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