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Glutamate Receptor, Ionotropic, Kainate 2 Proteins (GRIK2)

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Additionally we are shipping GRIK2 Antibodies (82) and GRIK2 Kits (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GRIK2 2898 Q13002
Rat GRIK2 GRIK2 54257 P42260
GRIK2 14806  
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Top GRIK2 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Cells Human Fc Tag   100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GRIK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) Interaction Partners

Human Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) interaction partners

  1. In the Han population in Central China, the polymorphisms of SNP rs9390754 in the GRIK2 gene may be associated with epilepsy susceptibility.

  2. Study demonstrates that co-assembly of recombinant kainate receptors (GluK1 (show GRIK1 Proteins) and GluK2) with the Neto1 (show NETO1 Proteins) and Neto2 (show NETO2 Proteins) auxiliary subunits alters their onset and recovery from desensitization in a subunit-dependent manner

  3. This study found in GRIK2 (glutamate (show GRIN1 Proteins) receptor, ionotropic kainate 2) was most significant and also showed significant correlations with gene expression.

  4. This study showed that Gluk2 association with obsessive-compulsive disorder.

  5. Parkin interac (show PARK2 Proteins)ts with the kainate receptor GluK2 subunit and regulates KAR function.

  6. High risk genetic markers of paranoid schizophrenia were GRIK2*ATG and GRIK2*TGG in Tatars.

  7. The present study reveals an additional mechanism for the regulation of GluK2-containing kainate receptors by Src (show SRC Proteins) family kinases, which may be of pathological significance in ischemic stroke.

  8. we found no association between rs1556995 in GRIK2 and clozapine-induced obsessive-compulsive (OC) symptoms, implying that that GRIK2 may not play a role in the development of OC symptoms in schizophrenia patients

  9. 14-3-3 (show YWHAQ Proteins) proteins are an important regulator of GluK2a-containing KARs (show KARS Proteins) and may contribute to the slow decay kinetics of native KAR (show HSD17B12 Proteins)-EPSCs.

  10. Kainate receptor GluK2a post-translational modifications differentially regulate association with 4.1N (show EPB41L1 Proteins) to control activity-dependent receptor endocytosis

Mouse (Murine) Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) interaction partners

  1. Loss of parkin (show PARK2 Proteins) function in primary cultured neurons causes GluK2 protein to accumulate in the plasma membrane.

  2. Interictal and ictal discharges are minimized in mice lacking the GluK2 subunit.

  3. 14-3-3 (show YWHAQ Proteins) proteins are an important regulator of GluK2a-containing KARs (show KARS Proteins) and may contribute to the slow decay kinetics of native KAR (show HSD17B12 Proteins)-EPSCs.

  4. This study demonistrated that grik2 gene expression in mouse dorsal raphe nucleus

  5. The results show that NETO2 (show NETO2 Proteins) is a kainate receptor subunit with significant effects on glutamate (show GRIN1 Proteins) signaling mechanisms in brain.

  6. GluR6 kainate receptors are critically involved in inhibiting transmission at both A delta and C fibre monosynaptic pathways. Presynaptic GluR5 (show GRIK1 Proteins) kainate receptors play limited role in inhibiting C fibre-activated pathway.

  7. Using kainate receptor knock-out mice, we show that subunits glutamate (show GRIN1 Proteins) receptor (GluR) 5 (show GRIK1 Proteins) and GluR6 play distinct roles in kainate-induced gamma oscillations and epileptiform burst activity.

  8. The facilitatory effects of kainate on mossy fiber synaptic transmission and plasticity are mediated by GLU (show GCG Proteins)(K6)-containing kainate receptors.

  9. In the present study, we used knock-out mice to explore the contribution of GluR5 (show GRIK1 Proteins) and GluR6 receptors to sensory responses, fear memory, and learning-related synaptic potentiation in the amygdala.

  10. The related kinases SGK2 (show SGK2 Proteins) and SGK3 (show SGK3 Proteins) similarly stimulate GluR6, but are less effective than SGK1 (show SGK1 Proteins).

GRIK2 Protein Profile

Protein Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Gene names and symbols associated with GRIK2

  • glutamate receptor, ionotropic, kainate 2 (GRIK2)
  • glutamate receptor, ionotropic, kainate 2 (grik2-b)
  • glutamate receptor, ionotropic, kainate 2 (grik2)
  • glutamate receptor, ionotropic, kainate 2 (Grik2)
  • glutamate receptor, ionotropic, kainate 2 (beta 2) (Grik2)
  • glutamate receptor, ionotropic, kainate 5 (GRIK5)
  • AW124492 protein
  • EAA4 protein
  • GLR6 protein
  • GluK2 protein
  • GLUK6 protein
  • Glur-6 protein
  • Glur6 protein
  • Glurbeta2 protein
  • GRIK2 protein
  • grik2-A protein
  • GRIK5 protein
  • MRT6 protein

Protein level used designations for GRIK2

glutamate receptor 6 , glutamate receptor, ionotropic kainate 2 , glutamate receptor, ionotropic, kainate 5 , bA487F5.1 , excitatory amino acid receptor 4 , gluR-6 , glutamate receptor form A , glutamate receptor form B , glutamate receptor form C , glutamate receptor form D , glutamate receptor form E , glutamate receptor ionotropic, kainate 2 , gluR beta-2 , glutamate receptor beta-2 , glutamate receptor, ionotropic, kainate 2

GENE ID SPECIES
462899 Pan troglodytes
100294518 Xenopus laevis
378603 Xenopus laevis
2898 Homo sapiens
481938 Canis lupus familiaris
615226 Bos taurus
54257 Rattus norvegicus
556013 Danio rerio
100733104 Cavia porcellus
428628 Gallus gallus
101122701 Ovis aries
14806 Mus musculus
100356816 Oryctolagus cuniculus
100516526 Sus scrofa
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