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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antibodies

The protein encoded by GRIN1 is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. Additionally we are shipping Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 Kits (23) and Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRIN1 2902 Q05586
GRIN1 24408 P35439
GRIN1 14810 P35438
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Top anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 Antibodies at antibodies-online.com

Showing 10 out of 258 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from K562 cells treated with PMA 125... Immunohistochemistry analysis of paraffin-embedded human brain, using ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using NMDAR1 (Phosp... Immunohistochemistry analysis of paraffin-embedded human brain, using ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using NMDAR1 (Ab-... Immunohistochemistry analysis of paraffin-embedded human brain tissue,... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Rat Goat Un-conjugated ELISA, WB ABIN185678 (2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated BI, IHC, WB Western blot analysis of NMDAR1 (First Panel). Lysate from a rat corte... Immunocytochemical detection of NMDAR1 (center panels). HEK-293 cells ... 0.1 mg Log in to see 5 to 6 Days
$265.55
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using ... Immunofluorescence analysis of A549 cells, using NMDAR1 (Phospho-Ser89... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using NMDAR1 (Ab-... Immunohistochemistry analysis of paraffin-embedded human brain tissue,... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$306.90
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-GRIN1 / NMDAR1 antibody IHC staining of human brain, cortex neuro... 50 μL Log in to see 8 to 10 Days
$451.00
Details

GRIN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus) , , , ,
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Mouse (Murine) , , , ,
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Top referenced anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 Antibodies

  1. Human Monoclonal GRIN1 Primary Antibody for BI, IHC - ABIN967491 : Brose, Huntley, Stern-Bach, Sharma, Morrison, Heinemann: Differential assembly of coexpressed glutamate receptor subunits in neurons of rat cerebral cortex. in The Journal of biological chemistry 1994 (PubMed)
    Show all 4 references for ABIN967491

  2. Human Polyclonal GRIN1 Primary Antibody for IHC, ELISA - ABIN1531928 : Foldes, Rampersad, Kamboj: Cloning and sequence analysis of cDNAs encoding human hippocampus N-methyl-D-aspartate receptor subunits: evidence for alternative RNA splicing. in Gene 1993 (PubMed)

  3. Human Polyclonal GRIN1 Primary Antibody for WB - ABIN362728 : Tyszkiewicz, Gu, Wang, Cai, Yan: Group II metabotropic glutamate receptors enhance NMDA receptor currents via a protein kinase C-dependent mechanism in pyramidal neurones of rat prefrontal cortex. in The Journal of physiology 2004 (PubMed)

  4. Rat (Rattus) Polyclonal GRIN1 Primary Antibody for ELISA, WB - ABIN185678 : Rajji, Chapman, Eichenbaum, Greene: The role of CA3 hippocampal NMDA receptors in paired associate learning. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)

More Antibodies against Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. Knockdown of PKD1 (show PKD1 Antibodies) did not affect NMDAR internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR-mediated synaptic functions.

  2. Study found GluN receptor subunit-specific changes in mixed subcortical ischemic vascular dementia(SIVD)/Alzheimer's disease(AD) (decreased GluN1) and SIVD (increased GluN2A (show GRIN2A Antibodies) and 2B), likely reflecting interaction of ischemic neurovascular and AD processes

  3. The results of this study suggested that GRIN1 mutations cause encephalopathy resulting in seizures and movement disorders.

  4. Genome-wide significant marker, SNP rs524991, and an association of seropositivity with influenza autoantibodies status, we provide genetic and environmental risk factors of NMDAR-autoantibodies formation

  5. Epigenetic changes in GRIN1, in combination with experiences of maltreatment, may confer risk for depression in children.

  6. Reduction in NR1 and NR2C (show GRIN2C Antibodies) in the DLPFC of people with schizophrenia may lead to altered NMDAR stoichiometry and provides compelling evidence for an endogenous NMDAR deficit in schizophrenia.

  7. Isolated GluN1/GluN3A (show GRIN3A Antibodies) receptors integrated into lipid bilayers responded to addition of either glycine or d-serine, but not glutamate, with a approximately 1 nm reduction in height of the extracellular domain

  8. the levels were comparable for complexes containing GluR2 (show GRIA2 Antibodies), GluR3 (show GRIA3 Antibodies) and GluR4 (show GRIA4 Antibodies) as well as 5-HT1A (show HTR1A Antibodies). Moreover, the levels of complexes containing muscarinic AChR M1, NR1 and GluR1 (show GRIA1 Antibodies) were significantly increased in male patients with AD.

  9. Results show that the expression and distribution of NMDA receptors subunits GluN1, GluN2A (show GRIN2A Antibodies) and GluN2B (show GRIN2B Antibodies) - together with that of postsynaptic protein PSD-95 (show DLG4 Antibodies) - are modified in Alzheimer's disease compared to normal aging

  10. B7T inhibition of NMDA current mediated by NR1/NR2B (show GRIN2B Antibodies) receptor.

Xenopus laevis Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. Establishment of late-phase long-term potentiation (L-LTP (show SCP2 Antibodies)) in vivo requires NMDAR activation in the postsynaptic tectal cells within a critical time window after LTP (show SCP2 Antibodies) induction.

  2. PIP2 supports the open state of NMDA receptors via the adaptor protein alpha-actinin (show ACTN1 Antibodies). PIP2 and alpha-actinin (show ACTN1 Antibodies) act like a two-component hinge keeping the channel gate in its open state.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. EphB2 (show EPHB2 Antibodies) prevents amyloid-beta-induced depletion of cell surface GluN1 requiring the PDZ (show INADL Antibodies)-binding motif of EphB2 (show EPHB2 Antibodies)

  2. The authors demonstrate that nascent granule cells lacking NMDARs but rescued from apoptosis by overexpressing the pro-survival protein Bcl2 (show BCL2 Antibodies) were deficient in spine formation.

  3. GluN1 expression/enhanced glutamatergic function facilitates improved spatial memory in aldehyde dehydrogenase 2 deficient mice.

  4. Study compared neuronal injury in the hippocampal CA1 (show CA1 Antibodies) region to that in PCs and investigated the role of NMDA receptors GluN2B (show GRIN2B Antibodies) and GluN1 in Purkinje cell injury in a mouse model of cardiac arrest and cardiopulmonary resuscitation

  5. selective disruption of Grin1 within central amygdala CRF (show CRH Antibodies) neurons strongly enhances fear memory

  6. Results suggest that NMDA-receptor(Grin1)-mediated synaptic plasticity in the dorsal striatum contributes to strategy shifting and that striatal projection neurons of the direct pathway are particularly relevant for this process

  7. Studied whether H2S supplementation reduces NMDA-R and MMP-9 (show MMP9 Antibodies)-induced dysfunction in diabetic kidney.

  8. Studies provide evidence that N-methyl-D-aspartate receptor dependent neural signaling in the mPFC is a component of a neural mechanism for disambiguating the meaning of fear signals.

  9. This study demonstrated that the knockout of the GRIN1 gene that a selective decrease in dentate gyrus GluN1 is sufficient to decrease the glutamate concentrations .

  10. findings suggest that medial prefrontal cortex and CA3 (show CA3 Antibodies) hippocampus glutamate N-methyl-D-aspartate receptors play selective roles in regulating compulsive and impulsive behavior, respectively.

Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antigen Profile

Protein Summary

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with GRIN1

  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (grin1) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1) antibody
  • NMDA receptor 1 (Nmdar1) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (Grin1) antibody
  • glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1) antibody
  • NADPH dependent diflavin oxidoreductase 1 (Ndor1) antibody
  • 4930447P04Rik antibody
  • GB19253 antibody
  • GluN1 antibody
  • GluRdelta1 antibody
  • GluRzeta1 antibody
  • GRIN1 antibody
  • M100174 antibody
  • MRD8 antibody
  • Ndor antibody
  • NMD-R1 antibody
  • NMDA1 antibody
  • Nmdar antibody
  • NMDAR1 antibody
  • NR1 antibody
  • Rgsc174 antibody

Protein level used designations for GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1 , NMDA-type glutamate receptor 1 , NMDA-type glutamate receptor subunit 1 , N-methyl-D-aspartate receptor 1 , glutamate [NMDA] receptor subunit zeta-1 , N-methyl-D-aspartate receptor channel, subunit zeta-1 , N-methyl-D-aspartate receptor subunit NR1 , NMD-R1 , glutamate [NMDA] receptor subunit zeta 1 , glutamate receptor ionotropic, NMDA 1 , N-methyl-D-aspartate glutamate receptor , NMDA R1 receptor C1 cassette , neurotransmitter receptor , Glutamate [NMDA] receptor subunit zeta-1 , glutamate receptor subunit zeta 1 , N-methyl-D-aspartate receptor , NMDA glutamate receptor , N-methyl-D-aspartate receptor type 1 , NADPH-dependent diflavin oxidoreductase 1

GENE ID SPECIES
780048 Xenopus (Silurana) tropicalis
100023485 Monodelphis domestica
406079 Apis mellifera
443281 Ovis aries
751779 Taeniopygia guttata
2902 Homo sapiens
24408 Rattus norvegicus
494007 Canis lupus familiaris
397953 Xenopus laevis
404296 Gallus gallus
14810 Mus musculus
78797 Mus musculus
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