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Glutamate Receptor, Metabotropic 6 (GRM6) ELISA Kits

has adenylate cyclase inhibiting metabotropic glutamate receptor activity\; may play a role in synaptic transmission between photoreceptor cells and ON-bipolar cells in the retina [RGD, Feb 2006].. Additionally we are shipping Metabotropic Glutamate Receptor 6 Antibodies (95) and Metabotropic Glutamate Receptor 6 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRM6 2916 O15303
GRM6 108072 Q5NCH9
GRM6 24419 P35349
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Top Metabotropic Glutamate Receptor 6 ELISA Kits at antibodies-online.com

Showing 4 out of 19 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse 7.81 pg/ml 31.25-2000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Human
96 Tests Log in to see 2 to 3 Days
$380.00
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Human
96 Tests Log in to see 11 to 13 Days
$785.71
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Rat
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for Metabotropic Glutamate Receptor 6 Interaction Partners

Human Glutamate Receptor, Metabotropic 6 (GRM6) interaction partners

  1. Two mutations in GRM6 gene have been identified in two consanguineous Pakistani families with congenital stationary night blindness.

  2. These data suggest differences in coupling of TRPM1 (show TRPM1 ELISA Kits) function to mGluR6 signaling explain different cellular responses to glutamate (show GRIN1 ELISA Kits) in the retina and the skin.

  3. We found 5 different mutations in GRM6, in congenital stationary night blindness.

  4. The selective thinning of the inner retinal layers in patients with GRM6 mutations suggests either reduced bipolar or ganglion cell numbers or altered synaptic structure in the inner retina.

  5. The results expand the mutation spectrum of NYX (show NYX ELISA Kits), CACNA1F (show CACNA1F ELISA Kits) and GRM6. They also suggest that NYX (show NYX ELISA Kits) mutations are a common cause of congenital stationary night blindness (CSNB (show CSN2 ELISA Kits)).

  6. The phenotype associated with GRM6 mutation is variable in terms of presentation, refractive error, visual acuity and macular function. ERGs are electronegative and suggest ON-pathway dysfunction.

  7. A positive association was observed between response to methadone and two variants in the genes MYOCD (show MYOCD ELISA Kits) and GRM6.

  8. Affected individuals in three of five families carried either compound heterozygous or homozygous mutations in GRM6.

  9. The ligand-binding and the poorly characterized cysteine-rich domains, in addition to the intracellular domains, have a pivotal role in correct trafficking of metabotropic glutamate (show GRIN1 ELISA Kits) receptors to the cell surface.

  10. A switch in G-protein coupling, in which glutamate775lysine loses G(o) subunit coupling but retains coupling to G(i), may explain the highly specialized metabotropic glutamate (show GRIN1 ELISA Kits) receptor mGlur6 phenotype.

Mouse (Murine) Glutamate Receptor, Metabotropic 6 (GRM6) interaction partners

  1. These results indicate that Grm6 nob7 is a new model of the complete form of congenital stationary night blindness.

  2. The mGluR6-KO phenotype showed negative effects on ribbon synapse formation.

  3. Diagnosis of concurrent Stargardt disease and CSNB (show CSN2 ELISA Kits) was made on the ophthalmic history; genetic testing revealed two previously reported mutations in the ABCA4 (show ABCA4 ELISA Kits) gene and two novel deletions in the GRM6 gene.

  4. the localization and stability of Cacna1s (show CACNA1S ELISA Kits) depend on the expression of mGluR6 and its cascade components, and they suggest that Cacna1s (show CACNA1S ELISA Kits) is part of the mGluR6 complex.

  5. The results suggested that the TRPM1 (show TRPM1 ELISA Kits) channel in metabotropic glutamate receptor 6-null rod bipolar cells is inactive. Rod bipolar cells in metabotropic glutamate receptor 6-null mice were hyperpolarized.

  6. These results demonstrate that TRPM1-L is a component of the ON bipolar cell (BC) transduction channel downstream of mGluR6 in ON BCs.

  7. The mGluR6 mRNA levels are altered in the young and adult rat retina of Royal College of Surgeons rat and suggest that the genetically induced degeneration of photoreceptors affects the expression of this receptor by the INL retinal neurons.

  8. In mGluR6-null mice, long-latency ON responses are observed in the visual cortex, indicating that they can be conducted reliably to higher visual areas.

  9. mGluR6 expression was limited to the outer plexiform layer

  10. Visual responses of Grm6(no b-wave3 (show WASF3 ELISA Kits)) retinal ganglion cells to light onset were abnormal.

Metabotropic Glutamate Receptor 6 (GRM6) Antigen Profile

Antigen Summary

has adenylate cyclase inhibiting metabotropic glutamate receptor activity\; may play a role in synaptic transmission between photoreceptor cells and ON-bipolar cells in the retina

Gene names and symbols associated with GRM6

  • glutamate receptor, metabotropic 6 (GRM6) antibody
  • metabotropic glutamate receptor 6 (MGLUR6) antibody
  • glutamate receptor, metabotropic 6 (Grm6) antibody
  • glutamate receptor, metabotropic 6a (grm6a) antibody
  • BC021919 antibody
  • CSNB1B antibody
  • Gm3 antibody
  • Gprc1f antibody
  • GRM6 antibody
  • mGlu6 antibody
  • mGluR6 antibody
  • nerg1 antibody
  • nob2 antibody
  • nob3 antibody
  • nob4 antibody
  • si:dkey-52h10.3 antibody

Protein level used designations for GRM6

metabotropic glutamate receptor 6 , G protein-coupled receptor GRM6 , G protein-coupled receptor, family C, group 1, member F , grm6 , mglur6a

GENE ID SPECIES
462323 Pan troglodytes
443292 Ovis aries
2916 Homo sapiens
108072 Mus musculus
24419 Rattus norvegicus
481452 Canis lupus familiaris
568484 Danio rerio
100009501 Oryctolagus cuniculus
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