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anti-Glutamate Receptor, Metabotropic 7 (GRM7) Antibodies

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Additionally we are shipping GRM7 Kits (18) and GRM7 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRM7 2917 Q14831
GRM7 108073 Q68ED2
GRM7 81672 P35400
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Top anti-GRM7 Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using GRM7 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using GRM7 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated IHC (fro) Western blot of mouse brain lysate showing the specific immunolabeling of the ~102k mGluR7 protein phosphorylated at Ser862. Immunolabeling is blocked by the phospho-peptide used as antigen (peptide) but not by the corresponding dephospho-peptide (not shown). 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GRM7 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-GRM7  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  GRM7 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB EB09243 (0.5µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemical staining of Brain (Neurons and Glia) using anti- GRM7 antibody ABIN122320 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using mGluR7 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR7 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB GRM7 Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GRM7 antibody detected the GRM7 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details

GRM7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , ,
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Top referenced anti-GRM7 Antibodies

  1. Cow (Bovine) Polyclonal GRM7 Primary Antibody for IHC (fro) - ABIN784604 : Suh, Pelkey, Lavezzari, Roche, Huganir, McBain, Roche: Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7. in Neuron 2008 (PubMed)
    Show all 4 references for ABIN784604

  2. Human Polyclonal GRM7 Primary Antibody for IF, ELISA - ABIN1535757 : Flor, Van Der Putten, Rüegg, Lukic, Leonhardt, Bence, Sansig, Knöpfel, Kuhn: A novel splice variant of a metabotropic glutamate receptor, human mGluR7b. in Neuropharmacology 1997 (PubMed)

  3. Human Polyclonal GRM7 Primary Antibody for WB - ABIN375137 : Vadasz, Saito, Gyetvai, Oros, Szakall, Kovacs, Prasad, Toth: Glutamate receptor metabotropic 7 is cis-regulated in the mouse brain and modulates alcohol drinking. in Genomics 2007 (PubMed)

More Antibodies against GRM7 Interaction Partners

Human Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

  1. Glutamate (show GRIN1 Antibodies) system genes have been associated with disease risk in recent analyses from the Psychiatric Genomics Consortium.

  2. results indicate that the GRM7 SNPs rs13353402 and rs1531939 might be associated with schizophrenia in Chinese Han population.

  3. results reported here do not support a role for GRM7 in ADHD

  4. Copy number variants at GRM7 may have a role in the etiology of bipolar disorder.

  5. For neither PCLO (show PCLO Antibodies) nor GRM7 we found a more associated variant. For SLC6A4 (show SLC6A4 Antibodies), we found a new SNP that showed a lower P-value than in the GAIN-MDD GWAS

  6. in an elderly male Han Chinese population, GRM7 SNP rs11928865 (TT) occurs more frequently in age-related hearing impairment patients with SL and AL phenotype patterns.

  7. These results provide preliminary evidence of an association between the GRM7 rs37952452 polymorphism and selective attention deficit and anxiety found within the Korean ADHD population

  8. Mixed modeling analyses explored the relationship of GRM7 haplotype and SNP genotypes with measures of auditory perception. GRM7 alleles are associated primarily with peripheral measures of hearing loss, and with speech detection in older adults.

  9. Copy number variations within GRM7 are not associated with schizophrenia in the Han Chinese population.

  10. Data sets demonstrated a region of association for major depressive disorder within GRM7. Thus, the significance of this finding remains uncertain.

Mouse (Murine) Glutamate Receptor, Metabotropic 7 (GRM7) interaction partners

  1. Analysis of mGluR7 (show GRM2 Antibodies) KO mice, c-Fos expression, and cerebral MMPIP microinjection indicate that inhibition of mGluR7 (show GRM2 Antibodies) impairs intermale aggression owing to information processing dysfunction within the bed nucleus of the stria terminalis

  2. muscle does not appear to require high levels of SMN (show STMN1 Antibodies) above what is produced by two copies of SMN2 (show SMN1 Antibodies)

  3. SAM68 (show KHDRBS1 Antibodies) is a physiological regulator of SMN2 (show SMN1 Antibodies) splicing in a spinal muscular atrophy mouse model.

  4. Hyperoxia treatment increased the inclusion of SMN2 (show SMN1 Antibodies) exon 7 in skeletal muscles and resulted in improved motor function.

  5. Elfn1 (show ELFN1 Antibodies) recruits mGluR7 (show GRM2 Antibodies) to synaptic sites.A trans interaction of Elfn1 (show ELFN1 Antibodies) and mGluR7 (show GRM2 Antibodies) controls targeted interneuron synapse development.

  6. GRM7 regulates the phosphorylation of CREB (show CREB1 Antibodies) protein and the expression of Yes-associated protein (YAP (show YAP1 Antibodies)) by directly interacting with CaM (show Calm2 Antibodies), which subsequently regulates the expression of CyclinD1 and ultimately affects early cortical development.

  7. Modeling the selective interaction between XAP044 and mGlu7's Venus flytrap domain, whose three-dimensional structure is already known, will facilitate future drug development supported by computer-assisted drug design

  8. The data of this study revealed very different roles for mGlu7 in amygdala synaptic transmission, fear learning and its expression

  9. These data suggest targeting mGlu7 receptors with selective antagonist drugs may be an effective and safe strategy for the treatment of anxiety disorders.

  10. Glutamate (show GRIN1 Antibodies) release mediated by GluR7 (show GRIK3 Antibodies) at nerve terminals is influenced by divalent calcium channel type Ca2 (show CA2 Antibodies)+ ionophore.

GRM7 Antigen Profile

Protein Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GRM7

  • glutamate receptor, metabotropic 7 (GRM7) antibody
  • metabotropic glutamate receptor 7 (MGLUR7) antibody
  • glutamate receptor, metabotropic 7 (Grm7) antibody
  • 6330570A01Rik antibody
  • BB176677 antibody
  • C030018L03 antibody
  • E130018M02Rik antibody
  • GLUR7 antibody
  • Gpr1g antibody
  • Gprc1g antibody
  • MGLU7 antibody
  • mGluR7 antibody

Protein level used designations for GRM7

metabotropic glutamate receptor 7 , mGluR7 , G protein-coupled receptor GRM7 , G protein-coupled receptor, family C, group 1, member G , mGlu7a receptor , metabotropic glutamate receptor mGluR7 , metabotropic glutamate receptor subtype 7b

GENE ID SPECIES
535362 Bos taurus
100171884 Pongo abelii
443520 Ovis aries
2917 Homo sapiens
108073 Mus musculus
81672 Rattus norvegicus
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