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anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antibodies

The protein encoded by GLS2 is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Additionally we are shipping Glutaminase 2 (Liver, Mitochondrial) Proteins (4) and Glutaminase 2 (Liver, Mitochondrial) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GLS2 27165 Q9UI32
GLS2 216456 Q571F8
GLS2 192268 P28492
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Top anti-Glutaminase 2 (Liver, Mitochondrial) Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB GLS2 Antibody (C-term E513) (ABIN652216) western blot analysis in mouse brain tissue lysates (35 µg/lane).This demonstrates the GLS2 antibody detected the GLS2 protein (arrow). GLS2 antibody(C-term E513) (ABIN652216) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated FACS, IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-GLS2/LGA Polyclonal Antibody, Unconjugated (ABIN1714808) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated IHC, WB GLS2 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain EpitheliaI cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X GLS2 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

GLS2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Glutaminase 2 (Liver, Mitochondrial) Antibodies

  1. Human Polyclonal GLS2 Primary Antibody for FACS, IHC - ABIN2437640 : Shimmura, Suzuki, Iwata, Tsuchiya, Ohno, Matsuzaki, Iwata, Kameno, Takahashi, Wakuda, Nakamura, Hashimoto, Mori: Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism. in Molecular autism 2013 (PubMed)

  2. Chicken Polyclonal GLS2 Primary Antibody for IHC, WB - ABIN2781319 : Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 (PubMed)

  3. Human Polyclonal GLS2 Primary Antibody for IHC (p), WB - ABIN652216 : Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)

More Antibodies against Glutaminase 2 (Liver, Mitochondrial) Interaction Partners

Human Glutaminase 2 (Liver, Mitochondrial) (GLS2) interaction partners

  1. As a p53 target, GLS2 mediates p53's function in metastasis suppression through inhibiting Rac1.

  2. IDO (show IDO1 Antibodies), through GCN2 (show EIF2AK4 Antibodies) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (show MYC Antibodies), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA (show LDHA Antibodies) and GLS2

  3. GABAergic neurons and astrocytes express Gls (show GLS Antibodies) and Gls2 isoenzymes in nucleus and mitochondria, in addition to glutamatergic neurons

  4. Phosphate-activated glutaminase and GAD65 (show GAD2 Antibodies)/67 concentrations are compared in Alzheimer's disease cerebellum versus normal cerebellum controls

  5. GLS2 expression is significantly decreased in hepatocellular carcinoma.

  6. Silencing GLS (show GLS Antibodies) or overexpressing GLS2 induces growth inhibition in glioma cell lines.

  7. GLS2 is acting, at least in part, downstream of p73 (show TP73 Antibodies) in neuronal differentiation and highlight a possible role of p73 (show TP73 Antibodies) in regulating neurotransmitter synthesis.

  8. combination of negative modulation of glutaminase (show GLS Antibodies) isoforms arising from GLS (show GLS Antibodies) gene with the introduction of the GLS2 gene product, GAB (show A1BG Antibodies), may in the future provide a useful means to curb glioblastoma growth in situ

  9. Epigenetic silencing of Gls2 via promoter hypermethylation is common in human liver and colon cancers.

  10. The present study was to investigate the potent effect of GLS2 on radioresistance of cervical carcinoma.

Mouse (Murine) Glutaminase 2 (Liver, Mitochondrial) (GLS2) interaction partners

  1. Study demonstrated expression of alternative transcripts of the mammalian Gls2 gene. Transcriptional mechanisms giving rise to GLS2 variants and isolation of novel GLS2 transcripts in human, rat and mouse are presented.

  2. Phosphate-activated glutaminase (GLS2) is a p53 (show TP53 Antibodies)-inducible regulator of glutamine (show GFPT1 Antibodies) metabolism and reactive oxygen species

Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antigen Profile

Protein Summary

The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.

Gene names and symbols associated with GLS2

  • glutaminase 2 (glsA2) antibody
  • glutaminase 2 (LOAG_03311) antibody
  • glutaminase 2 (liver, mitochondrial) (gls2) antibody
  • glutaminase 2 (liver, mitochondrial) (GLS2) antibody
  • glutaminase 2 (liver, mitochondrial) (Gls2) antibody
  • A330074B06Rik antibody
  • AI195532 antibody
  • Ga antibody
  • GLS antibody
  • hLGA antibody
  • Lga antibody
  • si:ch211-216k22.10 antibody

Protein level used designations for GLS2

glutaminase 2 , L-glutamine amidohydrolase , breast cell glutaminase , glutaminase I , glutaminase liver isoform, mitochondrial , phosphate-activated glutaminase , phosphate-dependent glutaminase , L-glutaminase , liver mitochondrial glutaminase , GLS

GENE ID SPECIES
8710836 Citrobacter rodentium ICC168
9940699 Loa loa
100006303 Danio rerio
27165 Homo sapiens
100686499 Canis lupus familiaris
539561 Bos taurus
216456 Mus musculus
192268 Rattus norvegicus
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